mTORC1 and mTORC2 have largely distinct functions in Purkinje cells

Making new contacts: the mTOR network in metabolism and signalling crosstalk

(2014) Mitsugu Shimobayashi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Gephyrin: a master regulator of neuronal function?

(2014) Shiva K. Tyagarajan et al.   NATURE REVIEWS NEUROSCIENCE

The Cerebellum, Sensitive Periods, and Autism

(2014) Samuel S.-H. Wang et al.   NEURON

The Neurology of mTOR

(2014) Jonathan O. Lipton et al.   NEURON

Dendrite Self-Avoidance Requires Cell-Autonomous Slit/Robo Signaling in Cerebellar Purkinje Cells

(2014) Daniel A. Gibson et al.   NEURON

Sustained Activation of mTORC1 in Skeletal Muscle Inhibits Constitutive and Starvation-Induced Autophagy and Causes a Severe, Late-Onset Myopathy

(2013) Perrine Castets et al.   Cell Metabolism

Synapse elimination in the developing cerebellum

(2013) Kouichi Hashimoto et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A protocol for concurrent high-quality immunohistochemical and biochemical analyses in adult mouse central nervous system

(2013) Tina Notter et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Ablation of the mTORC2 component rictor in brain or Purkinje cells affects size and neuron morphology

(2013) Venus Thomanetz et al.   JOURNAL OF CELL BIOLOGY

Inactivation of mTORC1 in the Developing Brain Causes Microcephaly and Affects Gliogenesis

(2013) D. Cloetta et al.   JOURNAL OF NEUROSCIENCE

mTORC2 controls actin polymerization required for consolidation of long-term memory

(2013) Wei Huang et al.   NATURE NEUROSCIENCE

mTOR complexes in neurodevelopmental and neuropsychiatric disorders

(2013) Mauro Costa-Mattioli et al.   NATURE NEUROSCIENCE

Long-term depression and other synaptic plasticity in the cerebellum

(2013) Tomoo HIRANO   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Autophagy in axonal and dendritic degeneration

(2013) Yi Yang et al.   TRENDS IN NEUROSCIENCES

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

A Comprehensive Small Interfering RNA Screen Identifies Signaling Pathways Required for Gephyrin Clustering

(2012) J. Wuchter et al.   JOURNAL OF NEUROSCIENCE

Neurofilament phosphorylation and their proline-directed kinases in health and disease

(2012) Anne Holmgren et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

(2012) Peter T. Tsai et al.   NATURE

Protocadherins mediate dendritic self-avoidance in the mammalian nervous system

(2012) Julie L. Lefebvre et al.   NATURE

Loss of Tsc2 in Purkinje cells is associated with autistic-like behavior in a mouse model of tuberous sclerosis complex

(2012) R. Michelle Reith et al.   NEUROBIOLOGY OF DISEASE

γ-Protocadherins Control Cortical Dendrite Arborization by Regulating the Activity of a FAK/PKC/MARCKS Signaling Pathway

(2012) Andrew M. Garrett et al.   NEURON

A Modified RMCE-Compatible Rosa26 Locus for the Expression of Transgenes from Exogenous Promoters

(2012) Jan S. Tchorz et al.   PLoS One

mTOR complex 2 signaling and functions

(2011) Won Jun Oh et al.   CELL CYCLE

Climbing fiber synapse elimination in cerebellar Purkinje cells

(2011) Masahiko Watanabe et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

D-Serine regulates cerebellar LTD and motor coordination through the δ2 glutamate receptor

(2011) Wataru Kakegawa et al.   NATURE NEUROSCIENCE

Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue by rapamycin

(2011) Robert P. Carson et al.   NEUROBIOLOGY OF DISEASE

Phosphoproteomic Profiling of In Vivo Signaling in Liver by the Mammalian Target of Rapamycin Complex 1 (mTORC1)

(2011) Gokhan Demirkan et al.   PLoS One

Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex

(2011) J. Goto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulated mTORC1-Dependent Translational Control: From Brain Disorders to Psychoactive Drugs

(2011) Emanuela Santini et al.   Frontiers in Behavioral Neuroscience

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

Quantitative Organization of GABAergic Synapses in the Molecular Layer of the Mouse Cerebellar Cortex

(2010) Federica Briatore et al.   PLoS One

Novel axonal distribution of neurofilament-H phosphorylated at the glycogen synthase kinase 3β-phosphorylation site in its E-segment

(2009) Takahiro Sasaki et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Intrinsic versus extrinsic determinants during the development of Purkinje cell dendrites

(2009) C. Sotelo et al.   NEUROSCIENCE

Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy

(2008) C. Florian Bentzinger et al.   Cell Metabolism

Synaptogenesis in the cerebellar cortex: Differential regulation of gephyrin and GABAA receptors at somatic and dendritic synapses of Purkinje cells

(2008) Laura Viltono et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Response of a Neuronal Model of Tuberous Sclerosis to Mammalian Target of Rapamycin (mTOR) Inhibitors: Effects on mTORC1 and Akt Signaling Lead to Improved Survival and Function

(2008) L. Meikle et al.   JOURNAL OF NEUROSCIENCE

Tuberous sclerosis

(2008) Paolo Curatolo et al.   LANCET

GABAergic synapses are formed without the involvement of dendritic protrusions

(2008) Corette J Wierenga et al.   NATURE NEUROSCIENCE

Structural study of Purkinje cell axonal torpedoes in essential tremor

(2008) Elan D. Louis et al.   NEUROSCIENCE LETTERS

Synapse formation and clustering of neuroligin-2 in the absence of GABAA receptors

(2008) A. Patrizi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA