Article
Clinical Neurology
John R. Gatti, Rachel Penn, Syed Ameen Ahmad, Lisa R. Sun
Summary: This study aimed to investigate the risk factors for seizures in children with moyamoya arteriopathy and their impact on neurological outcomes. The results showed that younger age and symptomatic presentation were associated with an increased likelihood of seizures, while older age and asymptomatic (radiographic) presentation were associated with a decreased likelihood of seizures. Furthermore, seizures were associated with worse functional outcomes.
PEDIATRIC NEUROLOGY
(2023)
Review
Clinical Neurology
Michelle H. Leppert, James F. Burke, Lynda D. Lisabethx, Tracy E. Madsen, Dawn O. Kleindorfer, Stefan Sillau, Lee H. Schwamme, Stacie L. Daugher, Cathy J. Bradley, Michael Ho, Sharon N. Poisson
Summary: This article aims to reconcile and synthesize existing evidence of sex differences in young adults with ischemic strokes. The results indicate that women have a higher risk of ischemic strokes than men among young adults under the age of 35, while the sex difference is not significant among young adults aged 35-45.
Article
Clinical Neurology
Sarah Ming Li Tan, Shi Hui Ong, Tseng Tsai Yeo, Vincent Diong Weng Nga, Effie Chew, Pui Kit Tam, Peijing Su, Megan B. J. Ng, Hui Shi Lim, Leonard L. L. Yeo, Vijay K. Sharma, Ching-Hui Sia, Mervyn Jun Rui Lim, Benjamin Yong-Qiang Tan
Summary: This study aimed to compare functional outcomes and return to work ability between ischemic stroke (IS) and hemorrhagic stroke (HS) in young adults. The results showed that IS patients had better functional outcomes and were more likely to return to work. However, many young stroke patients did not return to work despite good functional outcomes.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2023)
Article
Clinical Neurology
Sarah Ming Li Tan, Shi Hui Ong, Tseng Tsai Yeo, Vincent Diong Weng Nga, Effie Chew, Pui Kit Tam, Peijing Su, Megan B. J. Ng, Hui Shi Lim, Leonard L. L. Yeo, Vijay K. Sharma, Ching-Hui Sia, Mervyn Jun Rui Lim, Benjamin Yong-Qiang Tan
Summary: The study aimed to assess the functional outcomes and ability to return to work (RTW) in young adults with ischemic stroke (IS) and hemorrhagic stroke (HS). The results showed that IS patients were more likely to RTW compared to HS patients, but many young stroke patients did not RTW despite good functional outcomes. Longer hospitalization and higher NIHSS score on admission were associated with a lower likelihood of RTW.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2023)
Article
Clinical Neurology
Merel S. Ekker, Jamie I. Verhoeven, Mijntje M. I. Schellekens, Esther M. Boot, Mayte E. van Alebeek, Paul J. A. M. Brouwers, Renate M. Arntz, Gert W. van Dijk, Rob A. R. Gons, Inge W. M. van Uden, Tom den Heijer, Paul L. M. de Kort, Karlijn F. de Laat, Anouk G. W. van Norden, Sarah E. Vermeer, Marian S. G. van Zagten, Robert J. van Oostenbrugge, Marieke J. H. Wermer, Paul J. Nederkoorn, Thomas P. Zonneveld, Henk Kerkhoff, Fergus A. Rooyer, Frank G. van Rooij, Ido R. van den Wijngaard, Catharina J. M. Klijn, Anil M. Tuladhar, Frank-Erik de Leeuw
Summary: The study aims to identify risk factors and possible causes of cryptogenic ischemic stroke in young adults using a pediatric classification system. The results show that using the pediatric classification system provides new leads for the possible causes in cryptogenic stroke, and could potentially lead to more tailored treatment for young individuals with stroke.
Article
Clinical Neurology
Si Luo, Wenjie Zhan, Lanjiao Zhang, Chenying Zeng, Daojun Hong, Pu Fang, Qianxi Chen, Jing Lin
Summary: The angiographic differences in adult patients with moyamoya disease (MMD) do not increase the risk of ischemic pattern, except for involvement of the posterior cerebral artery (PCA), which is associated with an increased risk of ischemic stroke.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY
(2023)
Article
Health Care Sciences & Services
Laura Amaya Pascasio, Marina Blanco Ruiz, Rodrigo Milan Pinilla, Juan Manuel Garcia Torrecillas, Antonio Arjona Padillo, Cristina Del Toro Perez, Patricia Martinez-Sanchez
Summary: Recent research in Spain has shown an increased incidence of ischemic stroke (IS) in young adults, with a higher percentage of vascular risk factors. This study analyzed data from a nationwide inpatient sample and estimated the in-hospital incidence of IS and its comorbidities by sex and age group. The findings revealed a higher incidence of IS in men under the age of 50, and young adults with IS had a higher prevalence of vascular risk factors compared to the general population. These results provide important insights for primary and secondary prevention strategies.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Clinical Neurology
Mingyu Tang, Guangsong Han, Ming Yao, Bin Peng, Yicheng Zhu, Lixin Zhou, Jun Ni
Summary: This study applied a modified risk factor categorization to analyze the risk factor profiles of Chinese young patients with ischemic stroke and explored the sex and age differences in the distribution of risk factors. The results showed that atherosclerosis-related risk factors were the most common, and chronic systemic conditions were more prevalent in young patients and women.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Cheng-Loong Liang, Han-Jung Chen, Yi-Che Lee, Cheng-Chun Wu, Chon-Haw Tsai, Po-Lin Chen, Wei-Lun Chang, Po-Yen Yeh, Cheng-Yu Wei, Ming-Jun Tsai, Yu Sun, Chih-Hao Lin, Jiunn-Tay Lee, Ta-Chang Lai, Li-Ming Lien, Mei-Chen Lin, Cheng-Li Lin, Hao-Kuang Wang, Chung Y. Hsu
Summary: This study examined the impact of smoking on functional outcomes in young stroke patients in Taiwan. The results indicated that smokers had a higher risk of unfavorable functional outcomes at 3 months after stroke.
FRONTIERS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Junlin Lu, Jingyi Wang, Zhidong Lin, Guangchao Shi, Rong Wang, Yahui Zhao, Yuanli Zhao, Jizong Zhao
Summary: The study investigated the association between MMP-9 levels and phenotypes of moyamoya disease (MMD). Higher MMP-9 expression was found in adult MMD patients, especially in hemorrhagic-onset cases. Elevated serum MMP-9 level (>1,011 ng/ml) may serve as an independent risk predictor for hemorrhagic strokes in adult MMD patients.
FRONTIERS IN NEUROLOGY
(2021)
Article
Hematology
Lamia M'barek, Salma Sakka, Fatma Megdiche, Nouha Farhat, Khadija Maalla, Dhaker Turki, Sawsan Feki, Ahmed Rebai, Mariem Dammak, Choumous Kallel, Chokri Mhiri
Summary: The cumulative effect of both traditional and common genetic risk factors is associated with the recurrence of ischemic stroke. A specific genotype combination such as FVL/MTHFR increases the risk of a second cerebral ischemic attack.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
(2021)
Article
Health Care Sciences & Services
Yea Jin Jo, Dae Hyun Kim, Min Kyun Sohn, Jongmin Lee, Yong-Il Shin, Gyung-Jae Oh, Yang-Soo Lee, Min Cheol Joo, So Young Lee, Min-Keun Song, Junhee Han, Jeonghoon Ahn, Won Hyuk Chang, Yun-Hee Kim, Deog Young Kim
Summary: Stroke in young adults has increased and is more likely to be hemorrhagic compared to older adults. Lifestyle-related risk factors such as obesity, smoking, and heavy alcohol consumption are more common in the younger group, while other cardiovascular risk factors are more frequent in the older group.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Respiratory System
Elizabeth F. Smith, Naomi R. Hemy, Graham L. Hall, Andrew C. Wilson, Conor P. Murray, Shannon J. Simpson
Summary: This study aimed to investigate the respiratory outcomes for adult survivors of preterm birth and identify risk factors for poorer respiratory outcomes. The study found that adult survivors of preterm birth had various abnormalities in their respiratory system, including airflow obstruction, gas trapping, abnormalities in gas transfer and respiratory mechanics. It was also found that respiratory hospitalizations during childhood were associated with reduced peak lung function in adult preterm-born individuals.
Article
Radiology, Nuclear Medicine & Medical Imaging
Peiying Liu, Gongkai Liu, Marco C. Pinho, Zixuan Lin, Binu P. Thomas, Melissa Rundle, Denise C. Park, Judy Huang, Babu G. Welch, Hanzhang Lu
Summary: The study optimized and evaluated a resting-state BOLD functional MRI technique to measure cerebrovascular reactivity and demonstrated its relationship to neurosurgical treatment. The results showed that the technique provided a task-free method to assess cerebrovascular reserve and depicted the treatment effect of revascularization surgery in patients with Moyamoya disease, comparable to the reference standard of CO2 inhalation MRI.
Article
Clinical Neurology
Phuong Thao Do, Li-Ying Chen, Lung Chan, Chaur-Jong Hu, Li-Nien Chien
Summary: This study investigated the long-term incidence and risk factors for poststroke epilepsy (PSE) in young adults. The study found that stroke severity, aphasia, malignancy, and drug abuse were associated with an increased risk of PSE, while statin use was associated with a lower risk. Decreasing the severity of stroke, using statin medication, and controlling unhealthy behaviors can potentially reduce the development of PSE. Identification and intervention based on risk factors could lead to early management of PSE and reduce its harmful effects.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Chengjun Wang, Meng Zhao, Xiaofeng Deng, Jia Wang, Qingming Shu, Zhongli Jiang, Jizong Zhao
NEUROSURGICAL REVIEW
(2018)
Article
Clinical Neurology
Chengjun Wang, Meng Zhao, Xiaofeng Deng, Jia Wang, Zhongli Jiang, Jizong Zhao
NEUROSURGICAL REVIEW
(2018)
Article
Clinical Neurology
Meng Zhao, Xiaofeng Deng, Shuo Wang, Dong Zhang, Yan Zhang, Jizong Zhao
CLINICAL NEUROLOGY AND NEUROSURGERY
(2018)
Article
Clinical Neurology
Meng Zhao, Xiaofeng Deng, Dong Zhang, Shuo Wang, Yan Zhang, Rong Wang, Jizong Zhao
JOURNAL OF NEUROSURGERY
(2019)
Article
Clinical Neurology
Zhiqin Lin, Meng Zhao, Xiangrong Li, Junmei Wang, Ping Qiu, Folin Lan, Celin Guan, Dongxia Liao, Dongwei Shen, Jing Lu, Shuanglin Que, Zhongli Jiang
NEUROSURGICAL REVIEW
(2019)
Article
Clinical Neurology
Chengjun Wang, Meng Zhao, Jia Wang, Shuo Wang, Dong Zhang, Kai Wang, Jizong Zhao
JOURNAL OF CHILD NEUROLOGY
(2018)
Article
Clinical Neurology
Hu Yin, Xingju Liu, Dong Zhang, Yan Zhang, Rong Wang, Meng Zhao, Jizong Zhao
Article
Oncology
Chengjun Wang, Meng Zhao, Jia Wang, Dong Zhang, Shuo Wang, Jizong Zhao
MOLECULAR MEDICINE REPORTS
(2019)
Article
Clinical Neurology
Xiangrong Li, Chengjun Wang, Zhiqin Lin, Meng Zhao, Xiaohui Ren, Xiaohui Zhang, Zhongli Jiang
NEUROSURGICAL REVIEW
(2020)
Article
Clinical Neurology
Qian Zhang, Peicong Ge, Yonggang Ma, Dong Zhang, Rong Wang, Yan Zhang, Shuo Wang, Yong Cao, Meng Zhao, Jizong Zhao
JOURNAL OF CHILD NEUROLOGY
(2019)
Article
Clinical Neurology
Jiaxi Li, Yahui Zhao, Meng Zhao, Penghui Cao, Xingju Liu, Hao Ren, Dong Zhang, Yan Zhang, Rong Wang, Jizong Zhao
NEUROSURGICAL REVIEW
(2020)
Article
Clinical Neurology
Yonggang Ma, Meng Zhao, Xiaofeng Deng, Dong Zhang, Shuo Wang, Zheng Zeng, Qian Zhang, Jizong Zhao
JOURNAL OF CLINICAL NEUROSCIENCE
(2020)
Article
Clinical Neurology
Yong Cao, Songlin Yu, Qian Zhang, Tao Yu, Yanfang Liu, Zhenghui Sun, Meng Zhao, Wen Wang, Ji Zong Zhao
STROKE AND VASCULAR NEUROLOGY
(2020)
Article
Environmental Sciences
Luo Ru Tao, Wang Pei Jiong, Deng Xiao Feng, Zhou Shu Jie, Zhao Meng, Qian Jing, Zhang Dong, Wang Rong, Zhang Yan
BIOMEDICAL AND ENVIRONMENTAL SCIENCES
(2018)
Article
Clinical Neurology
Meng Zhao, Dong Zhang, Shuo Wang, Yan Zhang, Rong Wang, Xiaofeng Deng, Jizong Zhao
ACTA NEUROLOGICA BELGICA
(2018)
Article
Clinical Neurology
Guilu He, Jianhao Lin, Jing Ye, Fobao Huang, Changzhi Yan, Zesi Liu, Xiuming Zhou, Qiao Li, Liang Zhang
Summary: This article introduces long tunneled external ventricular drain (LTEVD), which effectively avoids multiple surgeries by connecting an external shunt valve. It allows visual control of drainage flow, prolongs catheter indwelling time, and eliminates the need for multiple surgeries.
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Vinay Suresh, H. S. Suresh, Bharath Raju, Himanshu Jindal, Ahmad Ozair
Summary: This study investigated the outcomes of postoperative discitis treated with debridement and a novel technique focused on reducing outpatient antibiotic requirement in a low- and middle-income country (LMIC) setting. The results showed that patients with medically refractory postoperative discitis potentially have good outcomes after debridement plus 2-week local antibiotic instillation in LMICs.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Beatrice C. Bono, Davide Milani, Fabio Ferreli, Simone Olei, Luca Raspagliesi, Maria Pia Tropeano, Giovanni B. Lasio, Federico Pessina
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Avi A. Gajjar, Shrey Patel, Raj Swaroop Lavadi, Rida Mitha, Rohit Prem Kumar, Tavis Taylor, Galal A. Elsayed, D. Kojo Hamilton, Nitin Agarwal
Summary: Art in neurosurgery has played a crucial role in the discipline for centuries. Medical illustrations help visualize anatomy and surgical procedures, contributing to education, surgical planning, and navigation.
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Joaquin Perez Zabala, Yamila Basilotta Marquez, Romina Arganaraz, Beatriz Mantese
Summary: We present a low-cost and easily accessible adaptation system for stereotactic procedures in infants. By using a headband cast technique, a stereotactic biopsy was successfully performed in a 5-month-old patient, achieving precise targeting, histopathological diagnosis, and no associated complications.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Muhammad Kusdiansah, Arnau Benet, Yosuke Suzuki, Kenichi Haraguchi, Nakao Ota, Kosumo Noda, Rokuya Tanikawa
Summary: Fusiform vertebral artery aneurysms are difficult to treat, and endovascular and open microsurgical treatments are used for different situations. This report presents a case with complex anatomy and branch involvement and describes the treatment strategy used.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Victor M. Lu
Summary: This review emphasizes four essential domains that should be considered when interpreting pediatric neurosurgical SRMAs and provides examples to ensure accurate and effective interpretation of findings in this niche.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Lapo Bonosi, Angelo Torrente, Filippo Brighina, Cateno Concetto Tito Petralia, Pietro Merlino, Chiara Avallone, Vincenzo Gulino, Roberta Costanzo, Lara Brunasso, Domenico Gerardo Iacopino, Rosario Maugeri
Summary: Corticocortical evoked potentials (CCEPs) have emerged as a valuable intraoperative monitoring technique in eloquent brain tumor surgery, aiding in preserving critical functional areas. Current research shows the potential of CCEPs in guiding surgical decision making, reducing the risk of postoperative neurological deficits, and mapping functional connectivity, but further research and standardization are needed.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Yuchen Duan, Dagang Feng, Min Zhu, Heng Qiu, Tong Li, Zhen Chen, Leiming Jiang, Yong Huang
Summary: This study aimed to compare the effect of different Modic changes (MC) grades on the cage subsidence rate after spinal interbody fusion surgery. A meta-analysis was conducted on relevant randomized controlled trials and cohort studies. The results showed that MC may be associated with a higher cage subsidence rate. With the increase in MC grades, the incidence of subsidence decreased gradually, but it was always higher than that in the non-Modic changes (NMC). Oblique lumbar interbody fusion may be a better treatment choice for lumbar degenerative disease with MC.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Brian F. Saway, Conor M. Cunningham, Mustafa Ismail, Alejandro M. Spiotta
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Joanna M. Roy, Michael M. Covell, Carmelo Venero Jr, Christian A. Bowers
Summary: Early exposure to neurosurgery during medical school is critical for improving recruitment into the specialty. However, about 30% of medical schools in the U.S. lack a neurosurgery program, limiting students' exposure to the field. Virtual education, facilitated by webinars during the pandemic, has advantages such as global outreach and accessibility for international medical students. This review identifies and describes 16 educational resources, serving as a guide for medical students interested in neurosurgery.
WORLD NEUROSURGERY
(2024)
