Article
Critical Care Medicine
Jialing He, Yu Zhang, Xin Cheng, Tiangui Li, Yangchun Xiao, Liyuan Peng, Yuning Feng, Jinxiao He, Pengfei Hao, Haidong Deng, Peng Wang, Weelic Chong, Yang Hai, Lvlin Chen, Chao You, Lu Jia, Fang Fang
Summary: This study aimed to investigate the association between white blood cell (WBC) counts and 90-day mortality in patients with intracerebral hemorrhage (ICH). The results showed that increased WBC count was significantly associated with higher 90-day mortality. Furthermore, the median and maximum WBC counts within the first week after admission were better predictors of 90-day mortality compared to the WBC count on admission.
NEUROCRITICAL CARE
(2023)
Article
Neurosciences
Guangshuo Li, Shang Wang, Yunyun Xiong, Hongqiu Gu, Yingyu Jiang, Xin Yang, Chunjuan Wang, Chuanying Wang, Zixiao Li, Xingquan Zhao
Summary: This study found that higher levels of blood glucose were associated with higher mortality and proportion of evacuation of intracranial hematoma in patients with intracerebral hemorrhage.
CNS NEUROSCIENCE & THERAPEUTICS
(2022)
Article
Clinical Neurology
Ping Lu, Lingyun Cui, Yu Wang, Kaijiang Kang, Hongqiu Gu, Zixiao Li, Liping Liu, Yilong Wang, Xingquan Zhao
Summary: This large-scale cross-sectional study found that short-term mortality was higher in patients with spontaneous intracerebral hemorrhage (SICH) when HbA1c levels were at or below 5.10%, regardless of the presence of diabetes mellitus (DM).
FRONTIERS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Joseph P. Broderick, James C. Grotta, Andrew M. Naidech, Thorsten Steiner, Nikola Sprigg, Kazunori Toyoda, Dar Dowlatshahi, Andrew M. Demchuk, Magdy Selim, J. Mocco, Stephan Mayer
Summary: Research in the acute management of intracerebral hemorrhage (ICH) over the past 35 years has shown that early treatment to control bleeding and minimize brain injury is crucial. However, current medical and surgical interventions have not yet shown significant benefits in large-scale trials, emphasizing the need for further research and improvement in the delivery of ICH therapies for better outcomes.
Article
Neurosciences
Felix Lehmann, Lorena M. Schenk, Matthias Schneider, Joshua D. Bernstock, Christian Bode, Valeri Borger, Florian Gessler, Erdem Gueresir, Alexis Hadjiathanasiou, Motaz Hamed, Marcus Mueller, Christian Putensen, Julian Zimmermann, Hartmut Vatter, Patrick Schuss
Summary: The study found that elevated levels of lactate and glucose at admission in patients with ICH were significantly associated with increased mortality at 90 days. Multivariate logistic regression analysis identified ICH score >= 3, as well as admission hyperlactatemia and hyperglycemia, as independent and significant predictors of 90-day mortality in patients with deep-seated ICH.
Article
Clinical Neurology
Bin Gao, Hongqiu Gu, Wengui Yu, Shimeng Liu, Qi Zhou, Kaijiang Kang, Jia Zhang, Zixiao Li, Xingquan Zhao, Yongjun Wang
Summary: The study revealed that a considerable number of patients with intracerebral hemorrhage presented with dehydration upon admission. Patients with dehydration had significantly lower risks of in-hospital mortality, especially among younger patients.
FRONTIERS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Jialing He, Yu Zhang, Tiangui Li, Haidong Deng, Peng Wang, Weelic Chong, Yang Hai, Lvlin Chen, Chao You, Lu Jia, Yezhong Wang, Fang Fang
Summary: This study evaluated the prognostic value of blood-based biomarkers, particularly the glucose-albumin ratio (GAR), in patients with spontaneous intracerebral hemorrhage (ICH). The results showed that GAR was superior to other biomarkers in predicting 90-day mortality in ICH patients. The prognostic value of GAR was successfully validated in an external independent cohort.
NEUROSURGICAL REVIEW
(2023)
Review
Clinical Neurology
Xiongjie Fu, Guoyang Zhou, Jianfeng Zhuang, Chaoran Xu, Hang Zhou, Yucong Peng, Yang Cao, Hanhai Zeng, Jianru Li, Feng Yan, Lin Wang, Gao Chen
Summary: Spontaneous intracerebral hemorrhage (ICH) is a devastating form of stroke with high morbidity, mortality, and disability rates. Research indicates that the development of white matter injury (WMI) following ICH is complex and determines the prognosis of patients. Comprehensive treatment and understanding the relationship between WMI and other brain cells may reveal therapeutic targets for ICH.
FRONTIERS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Felix Lehmann, Lorena M. Schenk, Joshua D. Bernstock, Christian Bode, Valeri Borger, Florian A. Gessler, Erdem Gueresir, Motaz Hamed, Anna-Laura Potthoff, Christian Putensen, Matthias Schneider, Julian Zimmermann, Hartmut Vatter, Patrick Schuss, Alexis Hadjiathanasiou
Summary: The study revealed that the ratio of red blood cell distribution width to platelet count (RPR) may serve as an independent inflammatory marker for prognostic assessment in deep-seated intracerebral hemorrhage (ICH), and is associated with 90-day mortality.
FRONTIERS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Jatinder S. Minhas, Tom J. Moullaali, Gabriel J. E. Rinkel, Craig S. Anderson
Summary: Blood pressure is an important factor in managing intracerebral hemorrhage and aneurysmal subarachnoid hemorrhage. However, there are controversies surrounding the management of blood pressure for these conditions. Current research involves analyzing patient data to determine the strength and direction of blood pressure changes and provide recommendations for clinical practice and future research.
Article
Clinical Neurology
Leonardo Lorente, Maria M. Martin, Agustin F. Gonzalez-Rivero, Antonia Perez-Cejas, Luis Ramos-Gomez, Juan J. Caceres, Jordi Sole-Violan, Jacobo J. Villacampa-Jimenez, Alejandro Jimenez
Summary: This study is the first to report higher serum Bcl2 levels in non-surviving SIH patients compared to surviving patients, showing an association between serum Bcl2 levels and SIH mortality.
NEUROLOGICAL SCIENCES
(2021)
Article
Clinical Neurology
Kristin Tveitan Larsen, Maiken Nordahl Selseth, Silje Holt Jahr, Vigdis Hillestad, Nojoud Koubaa, Else Charlotte Sandset, Ole Morten Ronning, Espen Saxhaug Kristoffersen
Summary: This study investigated the relationship between prehospital blood pressure (BP) and clinical and radiological outcomes in acute intracerebral hemorrhage patients. The results showed that elevated prehospital BP parameters were associated with in-hospital death and hematoma expansion. Changes in prehospital BP were not consistently associated with outcome. A possible U-shaped association between prehospital BP and in-hospital death needs further investigation.
Article
Clinical Neurology
Ronda Lun, Vignan Yogendrakumar, Greg Walker, Michel Shamy, Robert Fahed, Adnan Qureshi, Dar Dowlatshahi
Summary: The study validates revised definitions of hematoma expansion incorporating intraventricular hemorrhage expansion for predicting poor outcome, outperforming conventional definitions even after accounting for care limitations.
INTERNATIONAL JOURNAL OF STROKE
(2021)
Article
Neurosciences
Byung-Rae Cho, Dong-Kyu Jang, Kyung-Sool Jang, Byung-Hoo Moon, Hyunji Cho
Summary: This study aimed to evaluate predictors for intracerebral hemorrhage (ICH) and 1-month mortality after intravenous (IV) or intraarterial (IA) recanalization therapy for major cerebral artery occlusion in Korean patients. The results showed that the international normalized ratio (INR) and glucose may be strong modifiable predictors of critical ICH leading to death.
INTERNATIONAL JOURNAL OF NEUROSCIENCE
(2022)
Article
Endocrinology & Metabolism
Heng Yang, Wei Ni, Pengju Wei, Sicheng Li, Xinjie Gao, Jiabin Su, Hanqiang Jiang, Yu Lei, Liangfu Zhou, Yuxiang Gu
Summary: Inhibition of HDACs can reduce neuroinflammation and white matter damage after ICH by modulating microglia/macrophage polarization, leading to improved neurological functional recovery.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2021)
Article
Multidisciplinary Sciences
Min Kyun Na, Yu Deok Won, Choong Hyun Kim, Jae Min Kim, Jin Hwan Cheong, Je Il Ryu, Myung-Hoon Han
Article
Clinical Neurology
Myung-Hoon Han, Yu Deok Won, Min Kyun Na, Choong Hyun Kim, Jae Min Kim, Je Il Ryu, Hyeong-Joong Yi, Jin Hwan Cheong
Review
Clinical Neurology
Je Il Ryu, Myung Hoon Han, Jae Min Kim, Choong Hyun Kim, Jin Hwan Cheong
WORLD NEUROSURGERY
(2018)
Article
Clinical Neurology
Yu Deok Won, Min Kyun Na, Je-Il Ryu, Jin-Hwan Cheong, Jae-Min Kim, Choong-Hyun Kim, Myung-Hoon Han
WORLD NEUROSURGERY
(2018)
Article
Multidisciplinary Sciences
Yu Deok Won, Min Kyun Na, Choong Hyun Kim, Jae Min Kim, Jin Hwan Cheong, Je Il Ryu, Myung-Hoon Han
SCIENTIFIC REPORTS
(2018)
Article
Engineering, Environmental
Youngkyun Jung, Young Gun Ko, Taegu Do, Youngsang Chu, Ung Su Choi, Choong Hyun Kim
JOURNAL OF HAZARDOUS MATERIALS
(2019)
Article
Multidisciplinary Sciences
In-Suk Bae, Jae Min Kim, Jin Hwan Cheong, Myung-Hoon Han, Je Il Ryu
Article
Engineering, Electrical & Electronic
Ji Su Park, Chang Min Lee, Sang-Mo Koo, Choong Hyun Kim
IEEE SENSORS JOURNAL
(2020)
Article
Chemistry, Analytical
Ji Su Park, Sang-Mo Koo, Choong Hyun Kim
Summary: A technique was developed in the study to measure the ground reaction force using an insole device equipped with force sensing resistors, which accurately detects whether the wearer is standing or walking. This technique can significantly reduce classification errors and enable real-time classification of standing and walking states, making it suitable for wearable robot operations and remote monitoring of daily living activities.
Article
Oncology
Myung-Hoon Han, Jae Min Kim, Jin Hwan Cheong, Je Il Ryu, Yu Deok Won, Gun He Nam, Choong Hyun Kim
Summary: The efficacy of CIK immunotherapy for patients with pure GBM was evaluated, showing that it could prolong overall survival and progression-free survival.
FRONTIERS IN ONCOLOGY
(2022)
Article
Chemistry, Analytical
Ji Su Park, Choong Hyun Kim
Summary: This paper proposes a method for assessing gait disorders by observing changes in the center of pressure during the gait cycle. The authors introduce a polar gaitogram and two indices, the area ratio index and the slope of the tangential line, as objective measures for gait analysis. Experimental results demonstrate the potential of using wearable devices to assess gait disorders and differentiate between stroke patients and healthy adults.
Article
Chemistry, Multidisciplinary
Ji Su Park, Bohyun Lee, Shinsuk Park, Choong Hyun Kim
Summary: This study used ultra-wideband (UWB) sensors installed on shoes to measure distances between feet and proposed a method for estimating stride length, foot clearance, and foot progression angle. Ten healthy adults walked on a treadmill to acquire foot trajectory data. The results were compared with a motion capture system (MCS) and showed similar accuracy to a previous study using an inertial measurement unit (IMU). Thus, UWB sensors can be extensively applied to analyze mobile gait systems.
APPLIED SCIENCES-BASEL
(2023)
Article
Engineering, Manufacturing
Bohyun Lee, Ji Su Park, Shinsuk Park, Choong Hyun Kim
Summary: Gait disorders can significantly impact a patient's quality of life, especially when it comes to drop foot. This study proposes the use of a soft actuator made from shape memory alloy to reduce the weight of an ankle-foot orthosis (AFO) used in treating drop foot. The results showed improved ankle angle range and reduced power consumption, making the proposed SMA-AFO a potential treatment option for patients with drop foot.
INTERNATIONAL JOURNAL OF PRECISION ENGINEERING AND MANUFACTURING
(2023)
Article
Computer Science, Information Systems
Keun-Tae Kim, Jaehyung Lee, Hyungmin Kim, Choong Hyun Kim, Song Joo Lee
Article
Engineering, Manufacturing
Chang Min Lee, Jisu Park, Shinsuk Park, Choong Hyun Kim
INTERNATIONAL JOURNAL OF PRECISION ENGINEERING AND MANUFACTURING
(2020)
Article
Clinical Neurology
Guilu He, Jianhao Lin, Jing Ye, Fobao Huang, Changzhi Yan, Zesi Liu, Xiuming Zhou, Qiao Li, Liang Zhang
Summary: This article introduces long tunneled external ventricular drain (LTEVD), which effectively avoids multiple surgeries by connecting an external shunt valve. It allows visual control of drainage flow, prolongs catheter indwelling time, and eliminates the need for multiple surgeries.
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Vinay Suresh, H. S. Suresh, Bharath Raju, Himanshu Jindal, Ahmad Ozair
Summary: This study investigated the outcomes of postoperative discitis treated with debridement and a novel technique focused on reducing outpatient antibiotic requirement in a low- and middle-income country (LMIC) setting. The results showed that patients with medically refractory postoperative discitis potentially have good outcomes after debridement plus 2-week local antibiotic instillation in LMICs.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Beatrice C. Bono, Davide Milani, Fabio Ferreli, Simone Olei, Luca Raspagliesi, Maria Pia Tropeano, Giovanni B. Lasio, Federico Pessina
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Avi A. Gajjar, Shrey Patel, Raj Swaroop Lavadi, Rida Mitha, Rohit Prem Kumar, Tavis Taylor, Galal A. Elsayed, D. Kojo Hamilton, Nitin Agarwal
Summary: Art in neurosurgery has played a crucial role in the discipline for centuries. Medical illustrations help visualize anatomy and surgical procedures, contributing to education, surgical planning, and navigation.
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Joaquin Perez Zabala, Yamila Basilotta Marquez, Romina Arganaraz, Beatriz Mantese
Summary: We present a low-cost and easily accessible adaptation system for stereotactic procedures in infants. By using a headband cast technique, a stereotactic biopsy was successfully performed in a 5-month-old patient, achieving precise targeting, histopathological diagnosis, and no associated complications.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Muhammad Kusdiansah, Arnau Benet, Yosuke Suzuki, Kenichi Haraguchi, Nakao Ota, Kosumo Noda, Rokuya Tanikawa
Summary: Fusiform vertebral artery aneurysms are difficult to treat, and endovascular and open microsurgical treatments are used for different situations. This report presents a case with complex anatomy and branch involvement and describes the treatment strategy used.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Victor M. Lu
Summary: This review emphasizes four essential domains that should be considered when interpreting pediatric neurosurgical SRMAs and provides examples to ensure accurate and effective interpretation of findings in this niche.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Lapo Bonosi, Angelo Torrente, Filippo Brighina, Cateno Concetto Tito Petralia, Pietro Merlino, Chiara Avallone, Vincenzo Gulino, Roberta Costanzo, Lara Brunasso, Domenico Gerardo Iacopino, Rosario Maugeri
Summary: Corticocortical evoked potentials (CCEPs) have emerged as a valuable intraoperative monitoring technique in eloquent brain tumor surgery, aiding in preserving critical functional areas. Current research shows the potential of CCEPs in guiding surgical decision making, reducing the risk of postoperative neurological deficits, and mapping functional connectivity, but further research and standardization are needed.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Yuchen Duan, Dagang Feng, Min Zhu, Heng Qiu, Tong Li, Zhen Chen, Leiming Jiang, Yong Huang
Summary: This study aimed to compare the effect of different Modic changes (MC) grades on the cage subsidence rate after spinal interbody fusion surgery. A meta-analysis was conducted on relevant randomized controlled trials and cohort studies. The results showed that MC may be associated with a higher cage subsidence rate. With the increase in MC grades, the incidence of subsidence decreased gradually, but it was always higher than that in the non-Modic changes (NMC). Oblique lumbar interbody fusion may be a better treatment choice for lumbar degenerative disease with MC.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Brian F. Saway, Conor M. Cunningham, Mustafa Ismail, Alejandro M. Spiotta
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Joanna M. Roy, Michael M. Covell, Carmelo Venero Jr, Christian A. Bowers
Summary: Early exposure to neurosurgery during medical school is critical for improving recruitment into the specialty. However, about 30% of medical schools in the U.S. lack a neurosurgery program, limiting students' exposure to the field. Virtual education, facilitated by webinars during the pandemic, has advantages such as global outreach and accessibility for international medical students. This review identifies and describes 16 educational resources, serving as a guide for medical students interested in neurosurgery.
WORLD NEUROSURGERY
(2024)