Article
Oncology
Andrea Carai, Alessandro De Benedictis, Tommaso Calloni, Nicola Onorini, Giovanni Paterno, Franco Randi, Giovanna Stefania Colafati, Angela Mastronuzzi, Carlo Efisio Marras
Summary: Surgical resection is crucial for pediatric central nervous system tumors, and intraoperative ultrasound shows high predictive value in assessing tumor residue compared to postoperative MRI. Analysis indicates tumor histology significantly impacts the presence of residual tumor, while variables like tumor location, patient positioning, age, and initial tumor volume do not significantly affect ioUS predictive ability.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Fatih Incekara, Marion Smits, Linda Dirven, Eelke M. Bos, Rutger K. Balvers, Iain K. Haitsma, Joost W. Schouten, Arnaud J. P. E. Vincent
Summary: The study confirms that intraoperative B-mode ultrasound guided surgery leads to more frequent complete resection without harming patients, which helps to maximize the extent of glioblastoma resection.
FRONTIERS IN ONCOLOGY
(2021)
Article
Neurosciences
Benjamin Sass, Darko Zivkovic, Mirza Pojskic, Christopher Nimsky, Miriam H. A. Bopp
Summary: The results of this study demonstrate that navigated i3D ultrasound can accurately identify the boundaries of glioblastoma and positively influence the extent of resection during surgery.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Clinical Neurology
Cordelia Orillac, Walter Stummer, Daniel A. Orringer
Summary: The central goal in glioma surgery is to safely maximize extent of resection, especially in eloquent cortex, where the goal of maximal resection is balanced with neurological risk. New technologies such as fluorescence-guided surgery, intraoperative magnetic resonance imaging, and microscopic imaging methods have elevated the standards for maximal safe resection.
Article
Neurosciences
Hossein Mahboubi, William H. Slattery III, Mia E. Miller, Gregory P. Lekovic
Summary: Intra-operative assessment of residual tumor may be less accurate than early post-operative MRI, which can serve as a beneficial baseline for long-term surveillance.
Article
Medicine, Research & Experimental
Zhenxing Sun, Dan Yuan, Yaxing Sun, Yi Guo, Guoqin Wang, Peihai Zhang, James Wang, Wei Shi, Guihuai Wang
Summary: This study demonstrates that the use of yellow fluorescence aids in identifying tumor margin and residual tumor tissue in intramedullary spinal cord ependymoma resection, improving the surgical resection rate. The 3-month follow-up clinical outcomes show good functional recovery in patients in the fluorescein group, with no residual tumor tissue or recurrence.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
(2022)
Article
Oncology
Marco Skardelly, Marlene Kaltenstadler, Felix Behling, Irina Maeurer, Jens Schittenhelm, Benjamin Bender, Frank Paulsen, Juergen Hedderich, Mirjam Renovanz, Jens Gempt, Melanie Barz, Bernhard Meyer, Ghazaleh Tabatabai, Marcos Soares Tatagiba
Summary: The study indicates a continuous relationship between residual tumor volume and overall survival in glioblastoma patients, supporting the concept of maximum safe resection. The final accelerated failure time model includes various independent predictors of overall survival, leading to an improvement in predictive accuracy compared to established models. This model is suitable for clinical decision making and evaluating non-randomized studies.
FRONTIERS IN ONCOLOGY
(2021)
Article
Neurosciences
David Kis, Laszlo Szivos, Mark Rekecki, Bayan Salam Shukir, Adrienn Mate, Katalin Hideghety, Pal Barzo
Summary: Glioblastoma, the most frequent type of primary brain tumors, can be accurately defined using probabilistic tractography, which allows for individually planned surgery and irradiation, leading to increased chances of survival.
FRONTIERS IN NEUROSCIENCE
(2022)
Review
Endocrinology & Metabolism
Victor E. Staartjes, Alex Togni-Pogliorini, Vittorio Stumpo, Carlo Serra, Luca Regli
Summary: Around one fifth of patients undergoing pituitary adenoma resection convert from non-GTR to GTR after the use of ioMRI. Improvement in extent of resection and residual tumor volume can be achieved to a certain extent with ioMRI. Factors such as surgical technique and field strength do not seem to significantly affect the impact of ioMRI.
Review
Medicine, General & Internal
Arthur H. A. Sales, Juergen Beck, Oliver Schnell, Christian Fung, Bernhard Meyer, Jens Gempt
Summary: In this study, a comprehensive literature review was conducted to explore the current state and future trends of surgical treatment for glioblastoma (GBM), with a focus on recent research topics.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Oncology
Victoria Becerra, Jose Hinojosa, Santiago Candela, Diego Culebras, Mariana Alamar, Georgina Armero, Gaston Echaniz, David Artes, Josep Munuera, Jordi Muchart
Summary: This study presents the experience of using 1.5-T high-field intraoperative magnetic resonance imaging (ioMRI) for pediatric neuro-oncological procedures. The study found that ioMRI identified residual tumors in 14% of cases and prompted further resection without any security incidents. The conclusion of the study is that ioMRI is a safe and reliable tool in pediatric neuro-oncology surgery, maximizing tumor resection without causing neurological deficits or complications.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
George Vartholomatos, Georgios S. Markopoulos, Eyrysthenis Vartholomatos, Anna C. Goussia, Lefkothea Dova, Savvas Dimitriadis, Stefania Mantziou, Vaso Zoi, Anastasios Nasios, Chrissa Sioka, Athanasios P. Kyritsis, Spyridon Voulgaris, George A. Alexiou
Summary: Intraoperative Flow Cytometry (iFC) is a promising technique for glioma grading and resection margin assessment. It uses a fast cell cycle analysis protocol to evaluate the malignancy of tumor samples. The results showed that high-grade gliomas had a significantly higher tumor index and iFC could accurately identify malignant tissue in the resection margins. Comparative studies with other intraoperative adjuncts are needed.
Article
Radiology, Nuclear Medicine & Medical Imaging
Kailash Chaurasiya, Elena Kireeva, Mikhail Yadgarov, Dmitry Akhaladze, Yury Likar
Summary: This study evaluated the use of future remnant liver volume and the ratio of remnant liver volume to body weight in assessing liver function before hepatectomy in pediatric patients with liver tumors. The findings suggest that hepatobiliary scintigraphy can be used for future remnant liver function assessment in children with a remnant liver volume of less than 25% to prevent posthepatectomy liver failure.
CLINICAL NUCLEAR MEDICINE
(2023)
Article
Clinical Neurology
Domenique M. J. Muller, Pierre A. Robe, Hilko Ardon, Frederik Barkhof, Lorenzo Bello, Mitchel S. Berger, Wim Bouwknegt, Wimar A. Van den Brink, Marco Conti Nibali, Roelant S. Eijgelaar, Julia Furtner, Seunggu J. Han, Shawn L. Hervey-Jumper, Albert J. S. Idema, Barbara Kiesel, Alfred Kloet, Jan C. De Munck, Marco Rossi, Tommaso Sciortino, W. Peter Vandertop, Martin Visser, Michiel Wagemakers, Georg Widhalm, Marnix G. Witte, Aeilko H. Zwinderman, Philip C. De Witt Hamer
Summary: The study introduces eRV and eRI, which can better predict biopsy decisions, resectability, and survival rates. Expected residual tumor volume and expected resectability index can support surgical decisions.
JOURNAL OF NEUROSURGERY
(2021)
Review
Medicine, General & Internal
Alexander J. Schupper, Raymund L. Yong, Constantinos G. Hadjipanayis
Summary: Maximal safe resection is the standard of care for high-grade gliomas in neurosurgical treatment. Various advanced technologies, such as fluorescence-guided surgery, intraoperative imaging, neuromonitoring modalities, and microscopic imaging techniques, have been developed to improve intraoperative visualization of tumor tissue. These technologies aim to enhance the detection of tumor tissue beyond what conventional microsurgery allows, and future directions focus on improving intraoperative technologies.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Clinical Neurology
Taiichi Saito, Kazuhiko Sugiyama, Seiji Hama, Fumiyuki Yamasaki, Takeshi Takayasu, Ryo Nosaka, Yoshihiro Muragaki, Takakazu Kawamata, Kaoru Kurisu
NEUROSURGICAL REVIEW
(2018)
Article
Clinical Neurology
Taiichi Saito, Yoshihiro Muragaki, Takahiro Shioyama, Takashi Komori, Takashi Maruyama, Masayuki Nitta, Takayuki Yasuda, Junji Hosono, Saori Okamoto, Takakazu Kawamata
Article
Clinical Neurology
Taiichi Saito, Yoshihiro Muragaki, Manabu Tamura, Takashi Maruyama, Masayuki Nitta, Shunsuke Tsuzuki, Takakazu Kawamata
NEUROSURGICAL REVIEW
(2020)
Article
Clinical Neurology
Junji Hosono, Masayuki Nitta, Kenta Masui, Takashi Maruyama, Takashi Komori, Hideaki Yokoo, Taiichi Saito, Yoshihiro Muragaki, Takakazu Kawamata
WORLD NEUROSURGERY
(2019)
Article
Clinical Neurology
Shunsuke Nomura, Koji Yamaguchi, Hiroyuki Akagawa, Akitsugu Kawashima, Yosuke Moteki, Tatsuya Ishikawa, Yasuo Aihara, Taiichi Saito, Yoshikazu Okada, Takakazu Kawamata
CEREBROVASCULAR DISEASES
(2019)
Article
Clinical Neurology
Taiichi Saito, Yoshihiro Muragaki, Manabu Tamura, Takashi Maruyama, Masayuki Nitta, Shunsuke Tsuzuki, Satoko Fukuchi, Mana Ohashi, Takakazu Kawamata
JOURNAL OF NEUROSURGERY
(2020)
Article
Engineering, Biomedical
Manabu Tamura, Ikuma Sato, Takashi Maruyama, Kazuma Ohshima, Jean-Francois Mangin, Masayuki Nitta, Taiichi Saito, Hiroyuki Yamada, Shinji Minami, Ken Masamune, Takakazu Kawamata, Hiroshi Iseki, Yoshihiro Muragaki
INTERNATIONAL JOURNAL OF COMPUTER ASSISTED RADIOLOGY AND SURGERY
(2019)
Article
Oncology
Yasukazu Fukuya, Soko Ikuta, Takashi Maruyama, Masayuki Nitta, Taiichi Saito, Shunsuke Tsuzuki, Mikhail Chernov, Takakazu Kawamata, Yoshihiro Muragaki
JOURNAL OF NEURO-ONCOLOGY
(2019)
Article
Clinical Neurology
Masayuki Nitta, Yoshihiro Muragaki, Takashi Maruyama, Hiroshi Iseki, Takashi Komori, Soko Ikuta, Taiichi Saito, Takayuki Yasuda, Junji Hosono, Saori Okamoto, Shunichi Koriyama, Takakazu Kawamata
JOURNAL OF NEUROSURGERY
(2019)
Article
Clinical Neurology
Taiichi Saito, Yoshihiro Muragaki, Takashi Maruyama, Takashi Komori, Masayuki Nitta, Shunsuke Tsuzuki, Atsushi Fukui, Takakazu Kawamata
NEUROSURGICAL REVIEW
(2020)
Article
Clinical Neurology
Taiichi Saito, Yoshihiro Muragaki, Manabu Tamura, Takashi Maruyama, Masayuki Nitta, Shunsuke Tsuzuki, Atsushi Fukui, Takakazu Kawamata
JOURNAL OF NEUROSURGERY
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Taisuke Furuta, Tadahiko Kubo, Tomohiko Sakuda, Taiichi Saito, Kaoru Kurisu, Yoshihiro Muragaki, Nobuo Adachi
Summary: Intraoperative MRI was found to be effective in detecting and reducing residual tumor tissue in patients with GCTB after denosumab therapy. The detection rate of residual tumor by iMRI was 100% and the procedure was performed safely without complications. No adverse events or recurrences were observed during the follow-up period, indicating the potential of iMRI in preventing GCTB recurrence.
Article
Clinical Neurology
Taiichi Saito, Yoshihiro Muragaki, Takashi Maruyama, Kayoko Abe, Takashi Komori, Kosaku Amano, Seiichiro Eguchi, Masayuki Nitta, Shunsuke Tsuzuki, Atsushi Fukui, Takakazu Kawamata
Summary: The study revealed that the incidence of MTMS is significantly associated with diffuse glioma patients compared to meningioma and control groups. Furthermore, the presence of MTMS correlated significantly with shorter overall survival in patients with GBM, indicating its involvement in suppressing the anti-tumor immune response.
NEUROSURGICAL REVIEW
(2021)
Article
Pharmacology & Pharmacy
Tatsuya Kobayashi, Masayuki Nitta, Kazuhide Shimizu, Taiichi Saito, Shunsuke Tsuzuki, Atsushi Fukui, Shunichi Koriyama, Atsushi Kuwano, Takashi Komori, Kenta Masui, Taketoshi Maehara, Takakazu Kawamata, Yoshihiro Muragaki
Summary: Retrospective analysis showed that talaporfin sodium mediated photodynamic therapy (PDT) could potentially provide survival benefits for recurrent glioblastoma (GBM) patients, and its efficacy is independent of the pre-recurrence pathology.
Article
Clinical Neurology
Taiichi Saito, Yoshihiro Muragaki, Manabu Tamura, Takashi Maruyama, Masayuki Nitta, Shunsuke Tsuzuki, Atsushi Fukui, Shunichi Koriyama, Takakazu Kawamata
Summary: In 7 cases of glioma extending to the left frontal operculum, FLA was identified by functional mapping during awake craniotomy. CCEPs were successfully recorded using two 6-strand strip electrodes, and postoperative recovery of language function was monitored.
WORLD NEUROSURGERY
(2022)
Article
Clinical Neurology
Guilu He, Jianhao Lin, Jing Ye, Fobao Huang, Changzhi Yan, Zesi Liu, Xiuming Zhou, Qiao Li, Liang Zhang
Summary: This article introduces long tunneled external ventricular drain (LTEVD), which effectively avoids multiple surgeries by connecting an external shunt valve. It allows visual control of drainage flow, prolongs catheter indwelling time, and eliminates the need for multiple surgeries.
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Vinay Suresh, H. S. Suresh, Bharath Raju, Himanshu Jindal, Ahmad Ozair
Summary: This study investigated the outcomes of postoperative discitis treated with debridement and a novel technique focused on reducing outpatient antibiotic requirement in a low- and middle-income country (LMIC) setting. The results showed that patients with medically refractory postoperative discitis potentially have good outcomes after debridement plus 2-week local antibiotic instillation in LMICs.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Beatrice C. Bono, Davide Milani, Fabio Ferreli, Simone Olei, Luca Raspagliesi, Maria Pia Tropeano, Giovanni B. Lasio, Federico Pessina
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Avi A. Gajjar, Shrey Patel, Raj Swaroop Lavadi, Rida Mitha, Rohit Prem Kumar, Tavis Taylor, Galal A. Elsayed, D. Kojo Hamilton, Nitin Agarwal
Summary: Art in neurosurgery has played a crucial role in the discipline for centuries. Medical illustrations help visualize anatomy and surgical procedures, contributing to education, surgical planning, and navigation.
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Joaquin Perez Zabala, Yamila Basilotta Marquez, Romina Arganaraz, Beatriz Mantese
Summary: We present a low-cost and easily accessible adaptation system for stereotactic procedures in infants. By using a headband cast technique, a stereotactic biopsy was successfully performed in a 5-month-old patient, achieving precise targeting, histopathological diagnosis, and no associated complications.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Muhammad Kusdiansah, Arnau Benet, Yosuke Suzuki, Kenichi Haraguchi, Nakao Ota, Kosumo Noda, Rokuya Tanikawa
Summary: Fusiform vertebral artery aneurysms are difficult to treat, and endovascular and open microsurgical treatments are used for different situations. This report presents a case with complex anatomy and branch involvement and describes the treatment strategy used.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Victor M. Lu
Summary: This review emphasizes four essential domains that should be considered when interpreting pediatric neurosurgical SRMAs and provides examples to ensure accurate and effective interpretation of findings in this niche.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Lapo Bonosi, Angelo Torrente, Filippo Brighina, Cateno Concetto Tito Petralia, Pietro Merlino, Chiara Avallone, Vincenzo Gulino, Roberta Costanzo, Lara Brunasso, Domenico Gerardo Iacopino, Rosario Maugeri
Summary: Corticocortical evoked potentials (CCEPs) have emerged as a valuable intraoperative monitoring technique in eloquent brain tumor surgery, aiding in preserving critical functional areas. Current research shows the potential of CCEPs in guiding surgical decision making, reducing the risk of postoperative neurological deficits, and mapping functional connectivity, but further research and standardization are needed.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Yuchen Duan, Dagang Feng, Min Zhu, Heng Qiu, Tong Li, Zhen Chen, Leiming Jiang, Yong Huang
Summary: This study aimed to compare the effect of different Modic changes (MC) grades on the cage subsidence rate after spinal interbody fusion surgery. A meta-analysis was conducted on relevant randomized controlled trials and cohort studies. The results showed that MC may be associated with a higher cage subsidence rate. With the increase in MC grades, the incidence of subsidence decreased gradually, but it was always higher than that in the non-Modic changes (NMC). Oblique lumbar interbody fusion may be a better treatment choice for lumbar degenerative disease with MC.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Brian F. Saway, Conor M. Cunningham, Mustafa Ismail, Alejandro M. Spiotta
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Joanna M. Roy, Michael M. Covell, Carmelo Venero Jr, Christian A. Bowers
Summary: Early exposure to neurosurgery during medical school is critical for improving recruitment into the specialty. However, about 30% of medical schools in the U.S. lack a neurosurgery program, limiting students' exposure to the field. Virtual education, facilitated by webinars during the pandemic, has advantages such as global outreach and accessibility for international medical students. This review identifies and describes 16 educational resources, serving as a guide for medical students interested in neurosurgery.
WORLD NEUROSURGERY
(2024)