Article
Emergency Medicine
Ian Ward A. Maia, Lucas Oliveira J. E. Silva, Henrique Herpich, Luciano Diogo, Joao Carlos Batista Santana, Daniel Pedrollo, Mario Castro Alvarez Perez, Rafael Nicolaidis
Summary: The qSOFA score showed low sensitivity in predicting in-hospital mortality among patients with suspected infection, indicating that it should not be used as a screening tool for ruling out infection in the initial evaluation by emergency physicians or ED triage nurses in low-to-middle income countries.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Emergency Medicine
Ali Fuat Oduncu, Guclu Selahattin Kiyan, Sercan Yalcinli
Summary: The study compared the qSOFA, SIRS, and NEWS scoring systems in diagnosing sepsis and predicting mortality. It found that NEWS and qSOFA have similar prognosis and are superior to SIRS in both aspects.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Medicine, General & Internal
Ching-Chi Lee, Ching-Yu Ho, Po-Lin Chen, Chih-Chia Hsieh, William Yu Chung Wang, Chih-Hao Lin, Wen-Chien Ko
Summary: This study validated the effectiveness of Sepsis-3 criteria in patients with bacteremia, finding that inappropriate antimicrobial therapy or delayed source control significantly impacts the prognosis of septic patients, while having minimal effects on non-septic patients.
FRONTIERS IN MEDICINE
(2021)
Review
Infectious Diseases
Xia Qiu, Yu-Peng Lei, Rui-Xi Zhou
Summary: This study compared SIRS, SOFA, qSOFA, and NEWS for sepsis diagnosis and prognosis prediction. The results showed that NEWS independently demonstrated good diagnostic capability for sepsis, especially in high-income countries, while SOFA emerged as the optimal choice for predicting in-hospital mortality and can be used as a screening tool for 28/30-day mortality in low-income countries.
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY
(2023)
Article
Multidisciplinary Sciences
Riley Hazard, Danstan Bagenda, Andrew J. Patterson, Julia T. Hoffman, Steven J. Lisco, Olivier Urayeneza, Polyphile Ntihinyurwa, Christopher C. Moore
Summary: This study externally validated the Universal Vital Assessment (UVA) score in predicting mortality in patients with acute infection in Rwanda. The results showed that both the UVA score and amalgamated qSOFA score had good predictive ability for mortality in adult patients admitted with acute infection.
Article
Biochemistry & Molecular Biology
Sheng-Fen Wang, Tsung-Ting Tsai, Yun-Da Li, Ping-Yeh Chiu, Ming-Kai Hsieh, Jen-Chung Liao, Po-Liang Lai, Fu-Cheng Kao
Summary: This study aimed to investigate whether PEIDF could reduce the morbidity rate for patients with infectious spondylodiscitis. The results showed that compared to conventional open surgery, PEIDF significantly reduced surgical blood loss and intraoperative transfusions, with better decline of CRP. Patients undergoing conventional open surgery experienced more postoperative sepsis and prolonged-time for CRP normalization.
Article
Infectious Diseases
Miriam Kesselmeier, Mathias W. Pletz, Anna Leona Blankenstein, Andre Scherag, Torsten Bauer, Santiago Ewig, Martin Kolditz
Summary: This study validated the prognostic accuracy of using qSOFA score in patients with community-acquired pneumonia (CAP), showing that qSOFA-65 was less accurate in mortality prediction compared to CRB-65. For sensitive mortality prediction, adding the age criterion >= 65 years to qSOFA is recommended. The sepsis cut-off of >= 2 in qSOFA lacked sensitivity.
CLINICAL MICROBIOLOGY AND INFECTION
(2021)
Article
Infectious Diseases
Matteo Guarino, Edoardo Gambuti, Franco Alfano, Alfredo De Giorgi, Elisa Maietti, Andrea Strada, Francesco Ursini, Stefano Volpato, Giacomo Caio, Carlo Contini, Roberto De Giorgio
Summary: This study proposes a new tool, modified qSOFA, for early prognostic assessment of septic patients. Analysis of 1137 cases showed that MqSOFA had a better predictive ability for in-hospital mortality compared to qSOFA. By adding SpO2/FiO2 ratio to qSOFA, MqSOFA demonstrated improved sensitivity in detecting patient outcomes.
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
(2021)
Article
Emergency Medicine
Qi Guo, Hai-yan Li, Wei-dong Song, Hui Liu, Hai-qiong Yu, Yan-hong Li, Zhong-dong Lu, Li-hua Liang, Qing-zhou Zhao, Mei Jiang
Summary: In this study, qSOFA was found to predict mortality in CAP patients better than IDSA/ATS minor criteria and worse than CURB-65, with higher internal consistency and diagnostic value. The results suggest that qSOFA may serve as a useful tool for predicting mortality in CAP patients.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Article
Medicine, Research & Experimental
Yufei Xiao, Xiaotian Yan, Lingwei Shen, Qi Wang, Fugang Li, Dan Yang, Weiwei Wu, Yun Qian
Summary: This study found that qSOFA scores, CB and creatinine levels were significantly higher in the non-survival group of sepsis patients. CB and creatinine levels were identified as independent factors affecting 28-day mortality. The combined predictor value of CB and creatinine levels plus qSOFA score may be an important predictor of disease progression and prognosis in patients with sepsis and septic shock.
EXPERIMENTAL AND THERAPEUTIC MEDICINE
(2022)
Article
Medicine, Research & Experimental
Yaseen M. Arabi, Ramesh Kumar Vishwakarma, Hasan M. Al-Dorzi, Eman Al Qasim, Sheryl Ann Abdukahil, Fawaz K. Al-Rabeah, Huda Al Ghamdi, Ebtisam Al Ghamdi
Summary: The SCREEN trial aims to evaluate the effectiveness of electronic screening for sepsis in hospitalized ward patients through a stepped-wedge cluster randomized trial design.
Article
Infectious Diseases
Matteo Guarino, Benedetta Perna, Alfredo De Giorgi, Edoardo Gambuti, Franco Alfano, Elisa Maria Catanese, Stefano Volpato, Andrea Strada, Giacomo Caio, Carlo Contini, Roberto De Giorgio
Summary: This study compared different scoring tools in predicting in-hospital mortality for sepsis patients. The results showed that modified quick SOFA score (MqSOFA), NEWS, and lactate assay had better predictive ability compared to quick SOFA score (qSOFA). Age was also identified as an independent factor for negative outcomes.
Article
Infectious Diseases
S. M. Osama Bin Abdullah, Rune Husas Sorensen, Finn Erland Nielsen
Summary: This study found that in emergency department patients, a SOFA score of at least two had better prognostic accuracy for predicting 28-day mortality compared to SIRS and qSOFA. However, the overall accuracy of SOFA for predicting 28-day mortality was poor.
INFECTION AND DRUG RESISTANCE
(2021)
Article
Emergency Medicine
Takayuki Otani, Toshihisa Ichiba, Kazunori Seo, Hiroshi Naito
Summary: This study investigated the relationship between sepsis and bacteremia, and found that sepsis was more frequent in patients with bacteremia, with higher positive clinical scores. While some scores had high specificity or sensitivity, no single score had both high specificity and sensitivity.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Medicine, General & Internal
Chun-Yo Laih, Po-Jen Hsiao, Po-Fan Hsieh, Yu-De Wang, Chun-Ming Lai, Chao-Tung Yang, Chu-Hsing Lin, Chi-Ping Huang
Summary: This study aimed to evaluate the feasibility of using the SOFA and qSOFA scores to predict post-ureteroscopic lithotripsy (URSL) sepsis. The study found that older age, proximal ureteral stones, severe hydronephrosis, and high preoperative qSOFA or SOFA scores were significantly associated with postoperative sepsis.
