Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue

Increased Basement Membrane Components in Adipose Tissue During Obesity: Links With TGFβ and Metabolic Phenotypes

(2016) Sophie Reggio et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Inflammasomes: mechanism of action, role in disease and therapeutics

(2015) Haitao Guo et al.   NATURE MEDICINE

Immunological contributions to adipose tissue homeostasis

(2015) Joanna R. DiSpirito et al.   SEMINARS IN IMMUNOLOGY

Interleukin-1β mediates macrophage-induced impairment of insulin signaling in human primary adipocytes

(2014) Dan Gao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages

(2014) Mario Kratz et al.   Cell Metabolism

T Cell–Derived IL-22 Amplifies IL-1β–Driven Inflammation in Human Adipose Tissue: Relevance to Obesity and Type 2 Diabetes

(2014) Elise Dalmas et al.   DIABETES

IL-17 inhibits adipogenesis in part via C/EBPα, PPARγ and Krüppel-like factors

(2013) Mushtaq Ahmed et al.   CYTOKINE

Endothelial Cells From Visceral Adipose Tissue Disrupt Adipocyte Functions in a Three-Dimensional Setting: Partial Rescue by Angiopoietin-1

(2013) V. Pellegrinelli et al.   DIABETES

Roles of Chemokine Ligand-2 (CXCL2) and Neutrophils in Influencing Endothelial Cell Function and Inflammation of Human Adipose Tissue

(2013) Christine Rouault et al.   ENDOCRINOLOGY

Identification of Adipose Tissue Dendritic Cells Correlated With Obesity-Associated Insulin-Resistance and Inducing Th17 Responses in Mice and Patients

(2012) A. Bertola et al.   DIABETES

Effects of Gevokizumab on Glycemia and Inflammatory Markers in Type 2 Diabetes

(2012) C. Cavelti-Weder et al.   DIABETES CARE

TGFbeta Family Members Are Key Mediators in the Induction of Myofibroblast Phenotype of Human Adipose Tissue Progenitor Cells by Macrophages

(2012) Virginie Bourlier et al.   PLoS One

Adipose tissue macrophages: phenotypic plasticity and diversity in lean and obese states

(2011) David L Morris et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Lack of Interleukin-1 Receptor I (IL-1RI) Protects Mice From High-Fat Diet-Induced Adipose Tissue Inflammation Coincident With Improved Glucose Homeostasis

(2011) F. C. McGillicuddy et al.   DIABETES

IL-17 and IL-22 enhance skin inflammation by stimulating the secretion of IL-1β by keratinocytes via the ROS-NLRP3-caspase-1 pathway

(2011) Kyung-Ah Cho et al.   INTERNATIONAL IMMUNOLOGY

Blocking IL-17A Promotes the Resolution of Pulmonary Inflammation and Fibrosis Via TGF- 1-Dependent and -Independent Mechanisms

(2011) S. Mi et al.   JOURNAL OF IMMUNOLOGY

Stimulation of inflammatory gene expression in human preadipocytes by macrophage-conditioned medium: Upregulation of IL-6 production by macrophage-derived IL-1β

(2011) Adrian O’Hara et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

High Fat Diet Induces Formation of Spontaneous Liposarcoma in Mouse Adipose Tissue with Overexpression of Interleukin 22

(2011) Zheng Wang et al.   PLoS One

Defining macrophage phenotype and function in adipose tissue

(2011) Elise Dalmas et al.   TRENDS IN IMMUNOLOGY

Fibrosis in Human Adipose Tissue: Composition, Distribution, and Link With Lipid Metabolism and Fat Mass Loss

(2010) A. Divoux et al.   DIABETES

Bleomycin and IL-1β–mediated pulmonary fibrosis is IL-17A dependent

(2010) Mark S. Wilson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-17 Regulates Adipogenesis, Glucose Homeostasis, and Obesity

(2010) L. A. Zuniga et al.   JOURNAL OF IMMUNOLOGY

IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytesviaincreased IL-22 receptor expression

(2009) Mikiko Tohyama et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Treatment with an Interleukin 1 beta antibody improves glycemic control in diet-induced obesity

(2008) O. Osborn et al.   CYTOKINE

Macrophage-Secreted Factors Promote a Profibrotic Phenotype in Human Preadipocytes

(2008) Mayoura Keophiphath et al.   MOLECULAR ENDOCRINOLOGY