H2O-mediated isatin spiro-epoxide ring opening with NaCN: Synthesis of novel 3-tetrazolylmethyl-3-hydroxy-oxindole hybrids and their anticancer evaluation

Title
H2O-mediated isatin spiro-epoxide ring opening with NaCN: Synthesis of novel 3-tetrazolylmethyl-3-hydroxy-oxindole hybrids and their anticancer evaluation
Authors
Keywords
Azide-nitrile cycloaddition, Tetrazoles, 3-Hydroxy-oxindole, Anticancer, Isatin epoxide, Apoptosis
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 104, Issue -, Pages 11-24
Publisher
Elsevier BV
Online
2015-09-17
DOI
10.1016/j.ejmech.2015.09.025

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