Article
Ophthalmology
Yunzhi Xu, Yiming Ye, Zidong Chen, Jiangang Xu, Yangfan Yang, Yanmei Fan, Pingping Liu, Iok Tong Chong, Keming Yu, David C. C. Lam, Minbin Yu
Summary: This study assessed and compared corneal biomechanics in normal-tension glaucoma (NTG), high-tension glaucoma (HTG), and normal controls. The results showed that the corneas of NTG patients were softer than those of HTG patients and controls, which was associated with thinner corneal thickness.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Gongpu Lan, Michael D. Twa, Chengjin Song, JinPing Feng, Yanping Huang, Jingjiang Xu, Jia Qin, Lin An, Xunbin Wei
Summary: Clinical measurement of corneal biomechanics has significant implications in the diagnosis, tracking, and evaluation of ocular diseases. Advancements in interdisciplinary collaborations and testing methods, both ex vivo and in vivo, have contributed to our understanding of corneal biomechanics. However, in vivo measurement remains a challenge and ongoing research is focused on developing accurate approaches. This review discusses existing and emerging methods, such as corneal applanation, Brillouin microscopy, elastography, and optical coherence elastography, along with their fundamental concepts, analytical methods, and clinical status.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
(2023)
Article
Engineering, Biomedical
Yue Xuan, Andrew D. Wisneski, Zhongjie Wang, Matthew Lum, Shalni Kumar, Julia Pallone, Nick Flores, Justin Inman, Lilian Lai, Joanna Lin, Julius M. Guccione, Elaine E. Tseng, Liang Ge
Summary: The study focused on the regional failure properties of the healthy human ascending aorta, with an emphasis on experimental biomechanical properties and analysis of results. The experiment revealed the most vulnerable region to be the STJ area, consistent with clinical observations. Additionally, there was a significant correlation between failure stresses and elastic moduli.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2021)
Article
Ophthalmology
Marcos A. Crespo, Hiram J. Jimenez, Tanmay Deshmukh, Jose S. Pulido, Ahmed Saeed Saad, Frederick H. Silver, Dominick A. Benedetto, Christopher J. Rapuano, Zeba A. Syed
Summary: This study demonstrates the utility of VOCT as a non-invasive technique to measure the in vivo elastic modulus of the human cornea. The correlation between corneal thickness and elastic modulus was analyzed using OCT and Pentacam measurements. The results provide valuable insights into corneal structure and health.
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY
(2022)
Article
Construction & Building Technology
Yonghua Li, Lei Yao, Gaoxiang Chen, Weijian Zhao, Xiangang Liu
Summary: The tangent modulus method is a new settlement calculation method applied to hard soil with a strong structure. It considers the soil stress level and reflects the non-linear characteristics of settlement. A method for determining the tangent modulus of deep soil was proposed, as deep plate loading tests are difficult. The proposed method is feasible and more accurate than the traditional compression modulus.
Article
Engineering, Industrial
Hongli Hou, Guoqun Zhao, Liang Chen, Huiping Li
Summary: The study investigates the springback behavior of copper alloy after SPCD, revealing the effects of strain hardening, strain softening, and anisotropy on springback behavior. A new chord modulus model and 1-D ET model in a power exponential form were proposed to accurately predict the chord modulus and springback strain after SPCD. Results showed significant differences in springback behavior between SPCD and small plastic compressive deformation.
JOURNAL OF MATERIALS PROCESSING TECHNOLOGY
(2021)
Article
Nanoscience & Nanotechnology
Adam Sikora, Milan Gaff, Robert Nemeth
Summary: This study focuses on the impact of various factors on the properties of materials in the elastic and plastic regions of layered wood-based composites, highlighting the importance of thickness, densification, and nonwood components in the composite materials.
REVIEWS ON ADVANCED MATERIALS SCIENCE
(2021)
Article
Chemistry, Physical
Chih-Ming Chen, Huey-Ling Chang, Chun-Ying Lee
Summary: By investigating the use of 2-hydroxyethyl methacrylate (HEMA) toughening agent and various nano-powders, this study optimized the dynamic properties of epoxy composites. Through experimentation and analysis, the optimal composition ratios and performance enhancement effects were determined.
Article
Engineering, Multidisciplinary
Hung-Chun Yang, Tz-Cheng Chiu
Summary: An implicit integration scheme was developed for simulating the viscoplastic constitutive behavior of Sn3.0Ag0.5Cu solder and implemented into the finite element software ANSYS. The numerical procedure was used to study the responses of solder joints in an electronic assembly under temperature cycling conditions. Viscoplastic strain energy density accumulation over one temperature cycle was identified as a feasible parameter for evaluating the thermomechanical reliability of the solder joints.
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES
(2021)
Article
Mechanics
Peidong Lei, Shun Meng, Jian Wu, Zhanli Liu, Haroon Imtiaz, Huawei Feng, Junjie Zhou, Bin Liu
Summary: This paper clarifies controversies in the use of rate form constitutive expressions in finite deformation theory by distinguishing the related concepts and discussing the influence of different choices. It is proven that different stress-strain curves correspond to different constitutive models, and different rate form constitutive expressions can correctly reflect the constitutive model. The validity of different expressions can be evaluated using the element tangent stiffness matrix in FEM simulation.
INTERNATIONAL JOURNAL OF APPLIED MECHANICS
(2023)
Article
Engineering, Mechanical
Qiang Chen, Jianchang Zhu, Wenqiong Tu, Guannan Wang
Summary: In this study, a reformulated FVDAM framework is proposed for periodic multiphase materials, simplifying the solution process of differential equations by introducing the tangent plasticity matrix approach. The framework assesses errors in stress evaluation and allows large load increments using a quasi-Newton-Raphson strategy. The advantages of FVDAM theory over classical finite-element homogenization are highlighted, paving the way for its incorporation into commercial computational tools for solving challenging multiscale structural problems.
INTERNATIONAL JOURNAL OF PLASTICITY
(2021)
Article
Materials Science, Ceramics
Longbiao Li, Xiaojun Guo, Yufeng Liu
Summary: This paper analyzes the damage evolution of different fiber-reinforced ceramic-matrix composites (CMCs) under cyclic loading/unloading using the inverse tangent modulus (ITMs). Micro damage mechanisms are observed experimentally using X-ray computed tomography (XCT) and scanning electron microscopy (SEM). Based on the analysis of the damage mechanisms, a damage-based micromechanical constitutive model is developed to predict the cyclic loading/unloading curves and related damage parameters. The effects of composite's constitutive properties, peak stress, damage state, and interface properties on the cyclic loading/unloading damage evolution are discussed. The results show that the evolution curves of ITMs can be divided into two regions, with different growth rates in each region.
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
(2022)
Article
Mechanics
Huixin Wei, Xuliang Liu, Anna Dai, Linan Li, Chuanwei Li, Shibin Wang, Zhiyong Wang
Summary: This paper presents a method for in vivo characterization of facial soft tissue mechanical properties, using a bi-layer material model and a novel indentation apparatus. Experiments on artificial skins and four volunteers showed slight differences in Young's moduli of facial soft tissue at different locations.
INTERNATIONAL JOURNAL OF APPLIED MECHANICS
(2021)
Review
Engineering, Biomedical
Vishal Thomas, Jeremy Mercuri
Summary: This paper provides an in-depth investigation of the performance of naturally derived materials used in repairing/regenerating articular cartilage. While most natural constructs with native biomolecules have shown sub-optimal results in the past, current trends suggest that these materials have promising potential for effective scaffold fabrication.
ACTA BIOMATERIALIA
(2023)
Article
Engineering, Biomedical
N. Briot, G. Chagnon, N. Connesson, Y. Payan
Summary: This study proposes a method to measure breast tissue stiffness using an original aspiration device and inverse analysis. The results show that this method is feasible and the measurements are encouraging, which should be further validated in a clinical study.
CLINICAL BIOMECHANICS
(2022)
Article
Ophthalmology
Andrew K. C. Lam, Shirley K. Y. Tai, Jacky K. T. Chan, Raymond W. E. Ng
CURRENT EYE RESEARCH
(2019)
Article
Multidisciplinary Sciences
Andrew K. C. Lam, Ying Hon, Stanley Y. Y. Leung, Lu Shu-Ho, Jones Chong, David C. C. Lam
SCIENTIFIC REPORTS
(2019)
Article
Ophthalmology
Mei Zhao, David Alonso-Caneiro, Roger Lee, Allen M. Y. Cheong, Wing-Yan Yu, Ho-Yin Wong, Andrew K. C. Lam
OPTOMETRY AND VISION SCIENCE
(2020)
Article
Multidisciplinary Sciences
Hafi M. Khan, Alex Gentle, James A. Armitage, Chi-ho To, Andrew K. C. Lam
SCIENTIFIC REPORTS
(2020)
Article
Ophthalmology
Hetal D. Buckhurst, Bernard Gilmartin, Andrew Lam, Robert P. Cubbidge, Nicola S. Logan
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2020)
Article
Medicine, General & Internal
M. Hafi Khan, Andrew K. C. Lam, James A. Armitage, Lisa Hanna, Chi-ho To, Alex Gentle
JOURNAL OF CLINICAL MEDICINE
(2020)
Article
Ophthalmology
Sven Jonuscheit, Andrew K. C. Lam, Katrina L. Schmid, John Flanagan, Raul Martin, David Troilo
Summary: The article discusses the challenges faced by optometry schools in early to mid 2020 due to the COVID-19 pandemic. It highlights experiences from six universities in five countries on four continents, addressing strategies to minimize virus transmission risks and ensure safe clinical optometric teaching. The paper also looks at opportunities to enhance optometric education moving forward.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2021)
Article
Engineering, Biomedical
Menglin Guo, Mei Zhao, Allen M. Y. Cheong, Federico Corvi, Xin Chen, Siping Chen, Yongjin Zhou, Andrew K. C. Lam
Summary: In this study, a customized deep learning network was used for accurately segmenting the foveal avascular zone (FAZ) in the deep retinal layer, achieving an average Dice coefficient of 0.88 and an average Hausdorff distance of 17.79 through six-fold cross-validation. The proposed method is expected to have good clinical application value and provide a more objective, faster, and spatially quantitative approach for investigations related to dFAZ.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2021)
Review
Ophthalmology
Mei Zhao, Andrew K. C. Lam, Allen M. Y. Cheong
Summary: This review summarizes previous findings on structural and haemodynamic aspects of myopia-related vascular changes. It highlights the global concern of high prevalence of myopia and the potential issues caused by vascular changes associated with high myopia.
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2022)
Article
Multidisciplinary Sciences
Andrew Kwok-cheung Lam, Kenny Kin-hei Lau, Ho-yin Wong, Jasmine Pui-kwan Lam, Man-for Yeung
Summary: This study compared fixation deviation and stability with soft contact lens correction and device auto-focus system during OCTA measurements, finding that high myopes had better fixation stability when corrected with contact lenses.
SCIENTIFIC REPORTS
(2021)
Article
Ophthalmology
Fang-Yu Xu, Andrew K. C. Lam
Summary: This study aimed to evaluate the changes in intraocular pressure (IOP) during and after ocular compression and compare the differences between low and high myopia. The results showed that during compression, IOP gradually decreased and returned to baseline levels after the release of the compressive force.
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2023)
Article
Computer Science, Interdisciplinary Applications
Menglin Guo, Mei Zhao, Allen M. Y. Cheong, Houjiao Dai, Andrew K. C. Lam, Yongjin Zhou
VISUAL COMPUTING FOR INDUSTRY BIOMEDICINE AND ART
(2019)
Meeting Abstract
Ophthalmology
Andrew K. C. Lam, Shanica Hon, Sam Ka-Yue Lee, Shu-Ho Lu, Jones Chong, David Lam
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2019)
Proceedings Paper
Computer Science, Interdisciplinary Applications
Shu-Hao Lu, Ka Yue Lee, Jones Iok Tong Chong, Andrew K. C. Lam, Jimmy S. M. Lai, David C. C. Lam
PROCEEDINGS 2018 IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICINE (BIBM)
(2018)
Article
Ophthalmology
Andrew K. C. Lam, Stanley Y. Y. Leung, Ying Hon, Lu Shu-Ho, Kit-ying Wong, Pui-kwan Tiu, David C. C. Lam
CURRENT EYE RESEARCH
(2018)