CDKL5 localizes at the centrosome and midbody and is required for faithful cell division

Cellular and molecular introduction to brain development

(2016) Xiangning Jiang et al.   NEUROBIOLOGY OF DISEASE

Proliferation and Differentiation Deficits are a Major Convergence Point for Neurodevelopmental Disorders

(2016) Carl Ernst   TRENDS IN NEUROSCIENCES

CDKL5 and Shootin1 Interact and Concur in Regulating Neuronal Polarization

(2016) Mohammad Sarfaraz Nawaz et al.   PLoS One

Defects DuringMecp2Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms

(2015) Francesco Bedogni et al.   CEREBRAL CORTEX

Synaptic Synthesis, Dephosphorylation, and Degradation

(2015) Paolo La Montanara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytokinesis in Animal Cells

(2015) Pier Paolo D’Avino et al.   Cold Spring Harbor Perspectives in Biology

Methyl-CpG Binding Protein 2 (MeCP2) Localizes at the Centrosome and Is Required for Proper Mitotic Spindle Organization

(2014) Anna Bergo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitotic spindle multipolarity without centrosome amplification

(2014) Helder Maiato et al.   NATURE CELL BIOLOGY

Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling

(2014) Claudia Fuchs et al.   NEUROBIOLOGY OF DISEASE

Mapping Pathological Phenotypes in a Mouse Model of CDKL5 Disorder

(2014) Elena Amendola et al.   PLoS One

CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells

(2012) Emanuele Valli et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Centrosomes, chromosome instability (CIN) and aneuploidy

(2012) Benjamin D Vitre et al.   CURRENT OPINION IN CELL BIOLOGY

Midbody assembly and its regulation during cytokinesis

(2012) Chi-Kuo Hu et al.   MOLECULAR BIOLOGY OF THE CELL

HIPK2 Controls Cytokinesis and Prevents Tetraploidization by Phosphorylating Histone H2B at the Midbody

(2012) Cinzia Rinaldo et al.   MOLECULAR CELL

CDKL5 ensures excitatory synapse stability by reinforcing NGL-1–PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons

(2012) Sara Ricciardi et al.   NATURE CELL BIOLOGY

Towards a molecular architecture of centriole assembly

(2012) Pierre Gönczy   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Loss of CDKL5 disrupts kinome profile and event-related potentials leading to autistic-like phenotypes in mice

(2012) I.-T. J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

What We Know and Would Like to Know about CDKL5 and Its Involvement in Epileptic Encephalopathy

(2012) Charlotte Kilstrup-Nielsen et al.   NEURAL PLASTICITY

A novel transcript of cyclin-dependent kinase-like 5 (CDKL5) has an alternative C-terminus and is the predominant transcript in brain

(2011) Sarah L. Williamson et al.   HUMAN GENETICS

ExtrasynapticN-Methyl-d-aspartate (NMDA) Receptor Stimulation Induces Cytoplasmic Translocation of the CDKL5 Kinase and Its Proteasomal Degradation

(2011) Laura Rusconi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamics of endosomal sorting complex required for transport (ESCRT) machinery during cytokinesis and its role in abscission

(2011) N. Elia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CDKL5, a Protein Associated with Rett Syndrome, Regulates Neuronal Morphogenesis via Rac1 Signaling

(2010) Q. Chen et al.   JOURNAL OF NEUROSCIENCE

Centrioles, Centrosomes, and Cilia in Health and Disease

(2009) Erich A. Nigg et al.   CELL

Methyl-CpG-binding protein 2 is phosphorylated by homeodomain-interacting protein kinase 2 and contributes to apoptosis

(2009) Giorgia Bracaglia et al.   EMBO REPORTS

CDKL5 influences RNA splicing activity by its association to the nuclear speckle molecular machinery

(2009) Sara Ricciardi et al.   HUMAN MOLECULAR GENETICS

A mechanism linking extra centrosomes to chromosomal instability

(2009) Neil J. Ganem et al.   NATURE

CDKL5 Expression Is Modulated during Neuronal Development and Its Subcellular Distribution Is Tightly Regulated by the C-terminal Tail

(2008) Laura Rusconi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spastin Couples Microtubule Severing to Membrane Traffic in Completion of Cytokinesis and Secretion

(2008) James W. Connell et al.   TRAFFIC