Immune Signature of Enhanced Functional Avidity CD8+ T Cells in vivo Induced by Vaccinia Vectored Vaccine
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Title
Immune Signature of Enhanced Functional Avidity CD8+ T Cells in vivo Induced by Vaccinia Vectored Vaccine
Authors
Keywords
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Journal
Scientific Reports
Volume 7, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-02-03
DOI
10.1038/srep41558
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Note: Only part of the references are listed.- Functional Avidity and IL-2/Perforin Production Is Linked to the Emergence of Mutations within HLA-B*5701-Restricted Epitopes and HIV-1 Disease Progression
- (2014) M. Buggert et al. JOURNAL OF IMMUNOLOGY
- Boosting Functional Avidity of CD8+ T Cells by Vaccinia Virus Vaccination Depends on Intrinsic T-Cell MyD88 Expression but Not the Inflammatory Milieu
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- High Avidity CD8+ T Cells Efficiently Eliminate Motile HIV-Infected Targets and Execute a Locally Focused Program of Anti-Viral Function
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- Use of an In Vivo FTA Assay to Assess the Magnitude, Functional Avidity and Epitope Variant Cross-Reactivity of T Cell Responses Following HIV-1 Recombinant Poxvirus Vaccination
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- Human Antitumor CD8+ T Cells Producing Th1 Polycytokines Show Superior Antigen Sensitivity and Tumor Recognition
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- CTL Responses of High Functional Avidity and Broad Variant Cross-Reactivity Are Associated with HIV Control
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- Increased sensitivity to antigen in high avidity CD8+ T cells results from augmented membrane proximal T-cell receptor signal transduction
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- Plasmodium-Host Interactions Directly Influence the Threshold of Memory CD8 T Cells Required for Protective Immunity
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- High-Functional-Avidity Cytotoxic T Lymphocyte Responses to HLA-B-Restricted Gag-Derived Epitopes Associated with Relative HIV Control
- (2011) C. T. Berger et al. JOURNAL OF VIROLOGY
- Antigen sensitivity and T-cell receptor avidity as critical determinants of HIV control
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- When Toll-like receptor and T-cell receptor signals collide: a mechanism for enhanced CD8 T-cell effector function
- (2010) D. Geng et al. BLOOD
- Influenza Epitope-Specific CD8+ T Cell Avidity, but Not Cytokine Polyfunctionality, Can Be Determined by TCR Clonotype
- (2010) J. M. Moffat et al. JOURNAL OF IMMUNOLOGY
- Protective Efficacy of Cross-Reactive CD8+ T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation Threshold
- (2010) Sophie A. Valkenburg et al. PLoS Pathogens
- Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity
- (2009) J. R. Almeida et al. BLOOD
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- (2008) M. Quigley et al. BLOOD
- Increased Cytotoxic T-Lymphocyte Epitope Variant Cross-Recognition and Functional Avidity Are Associated with Hepatitis C Virus Clearance
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- CD8+ T cell efficacy in vaccination and disease
- (2008) Victor Appay et al. NATURE MEDICINE
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