Cytochrome P450-2E1 promotes fast food-mediated hepatic fibrosis

Liver Fibrosis: From Pathogenesis to Novel Therapies

(2016) Ralf Weiskirchen et al.   DIGESTIVE DISEASES

Cytochrome P450-2E1 promotes aging-related hepatic steatosis, apoptosis and fibrosis through increased nitroxidative stress

(2016) Mohamed A. Abdelmegeed et al.   FREE RADICAL BIOLOGY AND MEDICINE

Berberine prevents progression from hepatic steatosis to steatohepatitis and fibrosis by reducing endoplasmic reticulum stress

(2016) Zhiguo Zhang et al.   Scientific Reports

Saturated fat and cholesterol are critical to inducing murine metabolic syndrome with robust nonalcoholic steatohepatitis

(2015) Jamie E. Mells et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The role of iNOS in cholesterol-induced liver fibrosis

(2015) Sarit Anavi et al.   LABORATORY INVESTIGATION

The role of CYP2A5 in liver injury and fibrosis: chemical-specific difference

(2015) Feng Hong et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Osteopontin neutralisation abrogates the liver progenitor cell response and fibrogenesis in mice

(2014) J D Coombes et al.   GUT

CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis

(2013) Mohamed A. Abdelmegeed et al.   FREE RADICAL BIOLOGY AND MEDICINE

Free cholesterol accumulation in hepatic stellate cells: Mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice

(2013) Kengo Tomita et al.   HEPATOLOGY

Multiple Hits, Including Oxidative Stress, as Pathogenesis and Treatment Target in Non-Alcoholic Steatohepatitis (NASH)

(2013) Akinobu Takaki et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Environmental Toxin–Linked Nonalcoholic Steatohepatitis and Hepatic Metabolic Reprogramming in Obese Mice

(2013) Ratanesh Kumar Seth et al.   TOXICOLOGICAL SCIENCES

Interaction of Clusterin and Matrix Metalloproteinase-9 and Its Implication for Epithelial Homeostasis and Inflammation

(2012) Shinwu Jeong et al.   AMERICAN JOURNAL OF PATHOLOGY

Liver cholesterol: is it playing possum in NASH?

(2012) Geoffrey C. Farrell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis

(2012) Mohamed A. Abdelmegeed et al.   JOURNAL OF HEPATOLOGY

Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance

(2011) Haihong Zong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Roles of PPARs in NAFLD: Potential therapeutic targets

(2011) Anne Tailleux et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

PPARα Expression Protects Male Mice from High Fat–Induced Nonalcoholic Fatty Liver

(2011) Mohamed A. Abdelmegeed et al.   JOURNAL OF NUTRITION

Nutrition and physical activity in NAFLD: An overview of the epidemiological evidence

(2011) Shira Zelber-Sagi   WORLD JOURNAL OF GASTROENTEROLOGY

Increased expression of cytochrome P450 2E1 in nonalcoholic fatty liver disease: Mechanisms and pathophysiological role

(2011) J. Aubert et al.   Clinics and Research in Hepatology and Gastroenterology

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection

(2010) Brad Q. Starley et al.   HEPATOLOGY

Overexpression of liver-specific cytochrome P4502E1 impairs hepatic insulin signaling in a transgenic mouse model of nonalcoholic fatty liver disease

(2009) Elango Kathirvel et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Cytochrome P450 2E1 contributes to ethanol-induced fatty liver in mice

(2008) Yongke Lu et al.   HEPATOLOGY

Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice

(2008) Douglas Osei-Hyiaman et al.   JOURNAL OF CLINICAL INVESTIGATION