Review
Nursing
Tsai Rung Lin, Fan-Hao Chou, Hsiu-Hung Wang, Ruey-Hsia Wang
Summary: This study explores the physical and psychological effects of scar massage on burn patients. Through a systematic review and meta-analysis, it is found that scar massage decreases pain levels, improves scar thickness, reduces pruritus and anxiety among burn patients. However, there is no significant effect on depression. These findings suggest that scar massage is feasible and effective for burn patients in preventing and alleviating hypertrophic burn scarring.
JOURNAL OF CLINICAL NURSING
(2023)
Article
Medicine, General & Internal
So Young Joo, Yoon Soo Cho, Ji Won Yoo, Yi Hyun Kim, Rachael Sabangan, Seung Yeol Lee, Cheong Hoon Seo
Summary: Compression therapy using pressure garments can accelerate scar maturation and improve clinical symptoms. Monitoring the pressure range with a portable device can further enhance the efficacy of this therapy.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Medicine, General & Internal
Qingling Jiang, Junjie Chen, Fan Tian, Zhenmi Liu
Summary: The study aimed to evaluate the effects of silicone gel sheeting on hypertrophic scars, including 13 studies. Results showed that silicone gel sheeting compared to no treatment had some impact on the severity of scars and pain, but the certainty of the current evidence was low. There was also uncertainty in comparison with other treatment methods.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Review
Dermatology
Brittany Buhalog, Farah Moustafa, Lisa Arkin, Kachiu Lee, Katherine Siwy, Matthias Donelan, C. Scott Hultman, Peter R. Shumaker
Summary: Ablative fractional lasers (AFLs) have shown significant effectiveness in treating hypertrophic scars (HTS), but there is significant heterogeneity among studies that limits the generalizability of the results. Future studies should prioritize standardized protocols, including assessments of function and quality of life.
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2021)
Article
Cell Biology
Mengzhi Li, Peng Wang, Jingting Li, Fei Zhou, Shixin Huang, Shaohai Qi, Bin Shu
Summary: Hypertrophic scar is a pathological condition resulting from excessive tissue repair and it negatively affects patients' physical function and quality of life. Mechanical stress induces the expression of neuropilin 1 (NRP1) and inhibits the expression of YAP through LATS1, leading to the translocation of YAP into the nucleus.
CELL DEATH DISCOVERY
(2023)
Review
Critical Care Medicine
Sabrina Poppy Barnes, Yangmyung Ma, Bijendra Patel, Preetha Muthayya
Summary: Despite advancements in burn care, scar massage therapy has shown significant improvement for hypertrophic burn scar symptoms. Different massage techniques can be tailored to improve specific symptoms. Further large-scale randomized controlled trials are needed for further research.
JOURNAL OF BURN CARE & RESEARCH
(2023)
Review
Multidisciplinary Sciences
Yangmyung Ma, Sabrina P. Barnes, Yung-Yi Chen, Naiem S. Moiemen, Janet M. Lord, Amanda V. Sardeli
Summary: This study aimed to explore the effect of laser therapy on burn scars in adults, focusing on factors such as timing of treatment initiation, type of laser used, treatment interval, and presence of complications. The meta-analysis of previous studies showed that laser therapy significantly improved various aspects of burn scars, including vascularity, pliability, pigmentation, and scar height. The results also indicated that the efficacy of laser therapy was influenced by the time lapse after injury and the type of laser used.
Article
Critical Care Medicine
Jennifer Zuccaro, Charis Kelly, Manuela Perez, Andrea Doria, Joel S. Fish
Summary: Laser therapy has become a valuable treatment option for hypertrophic burn scars, with significant improvements in scar symptoms observed in pediatric patients in this study. The comprehensive scar assessment protocol utilized in this study demonstrated that laser therapy resulted in improvements in overall scarring and specific scar properties such as thickness, stiffness, and color.
JOURNAL OF BURN CARE & RESEARCH
(2021)
Article
Nursing
Jonathan Bayuo, Frances Kam Yuet Wong, Rose Lin, Jing Jing Su, Hammoda Abu-Odah
Summary: Living with post-burn scars is a challenging process, especially for individuals whose injuries are due to self-immolation. The findings highlight a latent yet ongoing process towards subjective recovery, and clinicians need to incorporate these processes into rehabilitation programs to provide support for burn survivors.
JOURNAL OF NURSING SCHOLARSHIP
(2023)
Article
Critical Care Medicine
Jung Hwan Lee, Chan Eol Seo, Woo Jin Song, Min Ju Kwon, Yang Seo Park, Jang Hyu Ko, Jong Won Hong, Myung Chul Lee
Summary: This study compared outcomes of different laser treatments for severe hypertrophic burn scars. The combination laser treatment showed significant improvement in scar reduction and multiple observer- and patient-reported outcomes. The shorter treatment period of the combination method may be an advantage in reducing morbidity associated with prolonged hypertrophic scars.
Review
Surgery
Peixuan Zhang, Qian Wu, Hongfan Ding, Ruiqi Bai, Fanting Meng, Xiao Xu, Minliang Chen
Summary: Combining pressure therapy and silicone therapy (PTS) is more effective than using pressure therapy alone (PT) in the treatment of hypertrophic scars, with potential benefits for scar height and pliability.
AESTHETIC PLASTIC SURGERY
(2023)
Review
Immunology
Joao Paulo Martins, Marlene Santos, Andre Martins, Miguel Felgueiras, Rui Santos
Summary: This paper presents a systematic review and meta-analysis of randomized controlled trials and test-negative designs to assess the vaccine effectiveness of seasonal influenza vaccines in humans aged 15 to 64 years. The study found that the match between the vaccine and the most prevalent circulating strains is the most important factor in the vaccine's effectiveness, increasing it by over 25%. The laboratory-confirmed method for influenza may introduce bias in estimating vaccine effectiveness.
Review
Surgery
Man-Yun Li, Wen-Kuan Chiu, Hsian-Jenn Wang, I-Fan Chen, Jin-Hua Chen, Ta-Pang Chang, Yu Ko, Chiehfeng Chen
Summary: BoNT-A is more effective than saline in treating scars, but steroids may have higher potency.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2022)
Review
Dermatology
Charles Choi, Ilya Mukovozov, Aria Jazdarehee, Roopal Rai, Muskaan Sachdeva, Maheshver Shunmugam, Kirill Zaslavsky, Stephanie Byun, Benjamin Barankin
Summary: This study conducted a meta-analysis on the treatment of hypertrophic scars (HTS) in adults. The results showed that silicone gel and laser modalities were effective in improving scar appearance. Additionally, the combination of silicone or 5-fluorouracil with intralesional triamcinolone was more effective than monotherapy. However, the study's limitations include the exclusion of studies that did not use the Vancouver Scar Scale and the need for further research on the efficacy of different treatment modalities.
AUSTRALASIAN JOURNAL OF DERMATOLOGY
(2022)
Article
Surgery
Nathanial Miletta, Katherine Siwy, Chad Hivnor, Jason Clark, Joshua Shofner, David Zurakowski, R. Rox Anderson, Kachiu Lee, Matthias Donelan
Summary: This study demonstrates that fractional ablative CO2 laser treatment leads to significant and sustained improvement in elasticity, thickness, appearance, and symptoms of mature hypertrophic burn scars. Objective measurements and patient/physician-reported outcomes both show significant improvements, with the effects lasting for at least 6 months post-treatment.