Multiple-stressor effects in an apex predator: combined influence of pollutants and sea ice decline on lipid metabolism in polar bears

Diet and metabolic state are the main factors determining concentrations of perfluoroalkyl substances in female polar bears from Svalbard

(2017) Sabrina Tartu et al.   ENVIRONMENTAL POLLUTION

Potentiation of ecological factors on the disruption of thyroid hormones by organo-halogenated contaminants in female polar bears ( Ursus maritimus ) from the Barents Sea

(2017) Sophie Bourgeon et al.   ENVIRONMENTAL RESEARCH

Sea ice-associated decline in body condition leads to increased concentrations of lipophilic pollutants in polar bears ( Ursus maritimus ) from Svalbard, Norway

(2017) Sabrina Tartu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Obesogens: an emerging threat to public health

(2016) Amanda S. Janesick et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Per- and polyfluoroalkyl substances (PFASs) – New endocrine disruptors in polar bears (Ursus maritimus)?

(2016) Kathrine Eggers Pedersen et al.   ENVIRONMENT INTERNATIONAL

Environmental Chemicals Modulate Polar Bear (Ursus maritimus) Peroxisome Proliferator-Activated Receptor Gamma (PPARG) and Adipogenesis in Vitro

(2016) Heli Routti et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Adaptations to polar life in mammals and birds

(2016) Arnoldus Schytte Blix   JOURNAL OF EXPERIMENTAL BIOLOGY

Geographical Area and Life History Traits Influence Diet in an Arctic Marine Predator

(2016) Sabrina Tartu et al.   PLoS One

Effects of pre-analytical processes on blood samples used in metabolomics studies

(2015) Peiyuan Yin et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Arctic marine mammal population status, sea ice habitat loss, and conservation recommendations for the 21st century

(2015) Kristin L. Laidre et al.   CONSERVATION BIOLOGY

EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals

(2015) A. C. Gore et al.   ENDOCRINE REVIEWS

Physiologically-based pharmacokinetic modelling of immune, reproductive and carcinogenic effects from contaminant exposure in polar bears (Ursus maritimus) across the Arctic

(2015) Rune Dietz et al.   ENVIRONMENTAL RESEARCH

Endocrine disruptors and obesity

(2015) Jerrold J. Heindel et al.   Nature Reviews Endocrinology

Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently

(2015) Roger Lille-Langøy et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Comprehensive and simultaneous coverage of lipid and polar metabolites for endogenous cellular metabolomics using HILIC-TOF-MS

(2014) Fan Fei et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Population Genomics Reveal Recent Speciation and Rapid Evolutionary Adaptation in Polar Bears

(2014) Shiping Liu et al.   CELL

Nuclear Receptors, RXR, and the Big Bang

(2014) Ronald M. Evans et al.   CELL

Chlorinated Persistent Organic Pollutants, Obesity, and Type 2 Diabetes

(2014) Duk-Hee Lee et al.   ENDOCRINE REVIEWS

Polar Bears Exhibit Genome-Wide Signatures of Bioenergetic Adaptation to Life in the Arctic Environment

(2014) Andreanna J. Welch et al.   Genome Biology and Evolution

Development of an Automated Multi-Injection Shotgun Lipidomics Approach Using a Triple Quadrupole Mass Spectrometer

(2014) John A. Bowden et al.   LIPIDS

mRNA expression of genes regulating lipid metabolism in ringed seals (Pusa hispida) from differently polluted areas

(2013) Martina Galatea Castelli et al.   AQUATIC TOXICOLOGY

State of the art paper Biochemistry of adipose tissue: an endocrine organ

(2013) Marisa Coelho et al.   Archives of Medical Science

A profile of carbohydrate metabolites in the fasting northern elephant seal

(2013) Cory D. Champagne et al.   Comparative Biochemistry and Physiology D-Genomics & Proteomics

Effect-Directed Analysis To Explore the Polar Bear Exposome: Identification of Thyroid Hormone Disrupting Compounds in Plasma

(2013) Eszter Simon et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Transthyretin-Binding Activity of Contaminants in Blood from Polar Bear (Ursus maritimus) Cubs

(2013) Jenny Bytingsvik et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Variation in the response of an Arctic top predator experiencing habitat loss: feeding and reproductive ecology of two polar bear populations

(2013) Karyn D. Rode et al.   GLOBAL CHANGE BIOLOGY

Evaluation of a Screening System for Obesogenic Compounds: Screening of Endocrine Disrupting Compounds and Evaluation of the PPAR Dependency of the Effect

(2013) Anna Pereira-Fernandes et al.   PLoS One

The Endocrine Disruptor 4-Nonylphenol Promotes Adipocyte Differentiation and Induces Obesity in Mice

(2012) Chan-juan Hao et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Metabolomic study of plasma from female mink (Neovison vison) with low and high residual feed intake during restrictive and ad libitum feeding

(2012) Mette Skou Hedemann et al.   Comparative Biochemistry and Physiology D-Genomics & Proteomics

Effects of climate warming on polar bears: a review of the evidence

(2012) Ian Stirling et al.   GLOBAL CHANGE BIOLOGY

Insulin promotes macrophage foam cell formation: potential implications in diabetes-related atherosclerosis

(2012) Young M Park et al.   LABORATORY INVESTIGATION

Novel qualitative aspects of tissue fatty acids related to metabolic regulation: Lessons from Elovl6 knockout

(2012) Hitoshi Shimano   PROGRESS IN LIPID RESEARCH

Mammalian Triacylglycerol Metabolism: Synthesis, Lipolysis, and Signaling

(2011) Rosalind A. Coleman et al.   CHEMICAL REVIEWS

Adiponectin Inhibits Lipolysis in Mouse Adipocytes

(2011) L. Qiao et al.   DIABETES

Exposure to mixtures of organohalogen contaminants and associative interactions with thyroid hormones in East Greenland polar bears (Ursus maritimus)

(2011) Gro D. Villanger et al.   ENVIRONMENT INTERNATIONAL

The emerging roles of fatty acid translocase/CD36 and the aryl hydrocarbon receptor in fatty liver disease

(2011) Jinhan He et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The evolution of the adipose tissue: A neglected enigma

(2011) Enzo Ottaviani et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Regional Contamination versus Regional Dietary Differences: Understanding Geographic Variation in Brominated and Chlorinated Contaminant Levels in Polar Bears

(2010) Melissa A. McKinney et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

A Novel Role for the Dioxin Receptor in Fatty Acid Metabolism and Hepatic Steatosis

(2010) Jung Hoon Lee et al.   GASTROENTEROLOGY

Influences of biofluid sample collection and handling procedures on GC–MS based metabolomic studies

(2010) Kiyoko Bando et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Role of fatty acid elongases in determination of de novo synthesized monounsaturated fatty acid species

(2010) Christopher D. Green et al.   JOURNAL OF LIPID RESEARCH

The prospects for polar bears

(2010) Andrew E. Derocher   NATURE

Model selection bias and Freedman’s paradox

(2009) Paul M. Lukacs et al.   ANNALS OF THE INSTITUTE OF STATISTICAL MATHEMATICS

Xenobiotic-Metabolizing Cytochromes P450 in Human White Adipose Tissue: Expression and Induction

(2009) S. Ellero et al.   DRUG METABOLISM AND DISPOSITION

Endocrine disrupters as obesogens

(2009) Felix Grün et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Minireview: The Case for Obesogens

(2009) Felix Grün et al.   MOLECULAR ENDOCRINOLOGY

Exposure and effects assessment of persistent organohalogen contaminants in arctic wildlife and fish

(2009) Robert J. Letcher et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Fat and Beyond: The Diverse Biology of PPARγ

(2008) Peter Tontonoz et al.   Annual Review of Biochemistry