Complement receptors C5aR1 and C5aR2 act differentially during the early immune response after bone fracture but are similarly involved in bone repair

Selective induction of IL-1β after a brief isoflurane anesthetic in children undergoing MRI examination

(2017) Emmett E. Whitaker et al.   Journal of Anesthesia

Osteoblast-specific overexpression of complement receptor C5aR1 impairs fracture healing

(2017) Stephanie Bergdolt et al.   PLoS One

Neutrophils contribute to fracture healing by synthesizing fibronectin + extracellular matrix rapidly after injury

(2016) Okan W. Bastian et al.   CLINICAL IMMUNOLOGY

Complement-coagulation crosstalk on cellular and artificial surfaces

(2016) Rebecca Wiegner et al.   IMMUNOBIOLOGY

Regulatory effects of anesthetics on nitric oxide

(2016) Wenguo Fan et al.   LIFE SCIENCES

Experimental design of complement component 5a-induced acute lung injury (C5a-ALI): a role of CC-chemokine receptor type 5 during immune activation by anaphylatoxin

(2015) Norman F. Russkamp et al.   FASEB JOURNAL

Boon and Bane of Inflammation in Bone Tissue Regeneration and Its Link with Angiogenesis

(2015) Katharina Schmidt-Bleek et al.   TISSUE ENGINEERING PART B-REVIEWS

Midkine-Deficiency Delays Chondrogenesis during the Early Phase of Fracture Healing in Mice

(2015) Melanie Haffner-Luntzer et al.   PLoS One

Exposure to 100% Oxygen Abolishes the Impairment of Fracture Healing after Thoracic Trauma

(2015) Julia Kemmler et al.   PLoS One

Expression and regulation of complement receptors by human natural killer cells

(2014) Xiaoyun Min et al.   IMMUNOBIOLOGY

Cutting Edge: Critical Role for C5aRs in the Development of Septic Lymphopenia in Mice

(2014) Jamison J. Grailer et al.   JOURNAL OF IMMUNOLOGY

Fracture healing: mechanisms and interventions

(2014) Thomas A. Einhorn et al.   Nature Reviews Rheumatology

Systemic inflammation induced by a thoracic trauma alters the cellular composition of the early fracture callus

(2013) Stefan Recknagel et al.   Journal of Trauma and Acute Care Surgery

Complement C3 and C5 Deficiency Affects Fracture Healing

(2013) Christian Ehrnthaller et al.   PLoS One

Terminally Differentiated CD8+ T Cells Negatively Affect Bone Regeneration in Humans

(2013) S. Reinke et al.   Science Translational Medicine

The role of complement in trauma and fracture healing

(2013) Markus Huber-Lang et al.   SEMINARS IN IMMUNOLOGY

C5L2: a controversial receptor of complement anaphylatoxin, C5a

(2012) Rui Li et al.   FASEB JOURNAL

Does complement play a role in bone development and regeneration?

(2012) Philipp Schoengraf et al.   IMMUNOBIOLOGY

C5aR Expression in a Novel GFP Reporter Gene Knockin Mouse: Implications for the Mechanism of Action of C5aR Signaling in T Cell Immunity

(2012) J. Dunkelberger et al.   JOURNAL OF IMMUNOLOGY

Absence of signaling into CD4+ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3+ regulatory T cells

(2012) Michael G Strainic et al.   NATURE IMMUNOLOGY

Fracture healing under healthy and inflammatory conditions

(2012) Lutz Claes et al.   Nature Reviews Rheumatology

Complement C3a and C5a modulate osteoclast formation and inflammatory response of osteoblasts in synergism with IL-1β

(2011) Anita Ignatius et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Role of C3a Receptors, C5a Receptors, and Complement Protein C6 Deficiency in Collagen Antibody-Induced Arthritis in Mice

(2011) N. K. Banda et al.   JOURNAL OF IMMUNOLOGY

C5aR-antagonist significantly reduces the deleterious effect of a blunt chest trauma on fracture healing

(2011) Stefan Recknagel et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

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(2011) Christian Ehrnthaller et al.   MOLECULAR MEDICINE

The Anaphylatoxin Receptor C5aR Is Present During Fracture Healing in Rats and Mediates Osteoblast Migration In Vitro

(2011) Anita Ignatius et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Efficient osteoclast differentiation requires local complement activation

(2010) Z. Tu et al.   BLOOD

The C5a Receptor (C5aR) C5L2 Is a Modulator of C5aR-mediated Signal Transduction

(2010) Claire E. Bamberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee

(2010) A. Michael Parfitt et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Molecular Intercommunication between the Complement and Coagulation Systems

(2010) U. Amara et al.   JOURNAL OF IMMUNOLOGY

The C5a Receptor Impairs IL-12-Dependent Clearance of Porphyromonas gingivalis and Is Required for Induction of Periodontal Bone Loss

(2010) S. Liang et al.   JOURNAL OF IMMUNOLOGY

Fracture healing in mice under controlled rigid and flexible conditions using an adjustable external fixator

(2010) Viktoria Röntgen et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

C3a and C5a Are Chemotactic Factors for Human Mesenchymal Stem Cells, Which Cause Prolonged ERK1/2 Phosphorylation

(2009) I. U. Schraufstatter et al.   JOURNAL OF IMMUNOLOGY

The role of the anaphylatoxins in health and disease

(2009) Andreas Klos et al.   MOLECULAR IMMUNOLOGY

Micro-computed tomography assessment of fracture healing: Relationships among callus structure, composition, and mechanical function

(2008) Elise F. Morgan et al.   BONE

The human complement fragment receptor, C5L2, is a recycling decoy receptor

(2008) Anne-Marie Scola et al.   MOLECULAR IMMUNOLOGY

Functional roles for C5a receptors in sepsis

(2008) Daniel Rittirsch et al.   NATURE MEDICINE