Structure-based modification of 3-/4-aminoacetophenones giving a profound change of activity on tyrosinase: From potent activators to highly efficient inhibitors

Published 2015 View Full Article

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Title
Structure-based modification of 3-/4-aminoacetophenones giving a profound change of activity on tyrosinase: From potent activators to highly efficient inhibitors
Authors
Keywords
Aminophenylethylidenethiosemicarbazide compounds, Tyrosinase activator, Tyrosinase inhibitor, SARs, Inhibition mechanism, Inhibitory kinetics
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 93, Issue -, Pages 255-262
Publisher
Elsevier BV
Online
2015-02-12
DOI
10.1016/j.ejmech.2015.02.013

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