In silico model of the human ClC-Kb chloride channel: pore mapping, biostructural pathology and drug screening
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Title
In silico model of the human ClC-Kb chloride channel: pore mapping, biostructural pathology and drug screening
Authors
Keywords
-
Journal
Scientific Reports
Volume 7, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-07-28
DOI
10.1038/s41598-017-07794-5
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Related references
Note: Only part of the references are listed.- Salt-losing nephropathy in mice with a null mutation of the Clcnk2 gene
- (2016) A. Grill et al. Acta Physiologica
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- (2016) Antonella Liantonio et al. JOURNAL OF HYPERTENSION
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- (2016) Haim Ashkenazy et al. NUCLEIC ACIDS RESEARCH
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- FAF-Drugs3: a web server for compound property calculation and chemical library design
- (2015) David Lagorce et al. NUCLEIC ACIDS RESEARCH
- ENCoM server: exploring protein conformational space and the effect of mutations on protein function and stability
- (2015) Vincent Frappier et al. NUCLEIC ACIDS RESEARCH
- PubChem Substance and Compound databases
- (2015) Sunghwan Kim et al. NUCLEIC ACIDS RESEARCH
- The hidden hand of chloride in hypertension
- (2015) Linsay McCallum et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- pKa predictions for proteins, RNAs, and DNAs with the Gaussian dielectric function using DelPhi pKa
- (2015) Lin Wang et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- I–J loop involvement in the pharmacological profile of CLC-K channels expressed in Xenopus oocytes
- (2014) Antonella Gradogna et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Deciphering key features in protein structures with the new ENDscript server
- (2014) Xavier Robert et al. NUCLEIC ACIDS RESEARCH
- CLC channel function and dysfunction in health and disease
- (2014) Gabriel Stölting et al. Frontiers in Physiology
- Membrane proteins, detergents and crystals: what is the state of the art?
- (2014) Patrick J. Loll Acta Crystallographica Section F-Structural Biology Communications
- Characterization of the mouse ClC-K1/Barttin chloride channel
- (2013) Sébastien L'Hoste et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Relation between sequence and structure in membrane proteins
- (2013) Mireia Olivella et al. BIOINFORMATICS
- One hundred thousand mouse clicks down the road: selected online resources supporting drug discovery collected over a decade
- (2013) Bruno O. Villoutreix et al. DRUG DISCOVERY TODAY
- NovelCLCNKBMutations Causing Bartter Syndrome Affect Channel Surface Expression
- (2013) Mathilde Keck et al. HUMAN MUTATION
- CLCNKB mutations causing mild Bartter syndrome profoundly alter the pH and Ca2+ dependence of ClC-Kb channels
- (2013) Olga Andrini et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- e-Drug3D: 3D structure collections dedicated to drug repurposing and fragment-based drug design
- (2012) Emilie Pihan et al. BIOINFORMATICS
- Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles
- (2012) Robert B. Best et al. Journal of Chemical Theory and Computation
- Dissecting a regulatory calcium-binding site of CLC-K kidney chloride channels
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- PDBTM: Protein Data Bank of transmembrane proteins after 8 years
- (2012) Dániel Kozma et al. NUCLEIC ACIDS RESEARCH
- CAVER 3.0: A Tool for the Analysis of Transport Pathways in Dynamic Protein Structures
- (2012) Eva Chovancova et al. PLoS Computational Biology
- PoPMuSiC 2.1: a web server for the estimation of protein stability changes upon mutation and sequence optimality
- (2011) Yves Dehouck et al. BMC BIOINFORMATICS
- OPM database and PPM web server: resources for positioning of proteins in membranes
- (2011) Mikhail A. Lomize et al. NUCLEIC ACIDS RESEARCH
- PubChem3D: a new resource for scientists
- (2011) Evan E Bolton et al. Journal of Cheminformatics
- Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels
- (2010) G Zifarelli et al. BRITISH JOURNAL OF PHARMACOLOGY
- A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels
- (2010) Antonella Gradogna et al. JOURNAL OF GENERAL PHYSIOLOGY
- Barttin Activates ClC-K Channel Function by Modulating Gating
- (2010) M. Fischer et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Modulation of ClC-K Channel Function by the Accessory Subunit Barttin
- (2010) F. Lang JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- A method and server for predicting damaging missense mutations
- (2010) Ivan A Adzhubei et al. NATURE METHODS
- Structure of a Eukaryotic CLC Transporter Defines an Intermediate State in the Transport Cycle
- (2010) Liang Feng et al. SCIENCE
- Molecular Pharmacology of Kidney and Inner Ear CLC-K Chloride Channels
- (2010) Antonella Gradogna et al. Frontiers in Pharmacology
- Physiology and pathophysiology of ClC-K/barttin channels
- (2010) Christoph Fahlke Frontiers in Physiology
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
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- (2009) Y Yu et al. CLINICAL GENETICS
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- CHARMM: The biomolecular simulation program
- (2009) B. R. Brooks et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- CLC Chloride Channels and Transporters: From Genes to Protein Structure, Pathology and Physiology
- (2008) Thomas J. Jentsch CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Global burden of blood-pressure-related disease, 2001
- (2008) Carlene MM Lawes et al. LANCET
- Molecular switch for CLC-K Cl- channel block/activation: Optimal pharmacophoric requirements towards high-affinity ligands
- (2008) A. Liantonio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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