Enzalutamide inhibits testosterone-induced growth of human prostate cancer xenografts in zebrafish and can induce bradycardia

Treatment of metastatic castration-resistant prostate cancer (mCRPC) with enzalutamide

(2016) Giulia Baciarello et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Novel Insights into Molecular Indicators of Response and Resistance to Modern Androgen-Axis Therapies in Prostate Cancer

(2016) John L. Silberstein et al.   Current Urology Reports

Bench-to-bedside development of agonists and antagonists of luteinizing hormone–releasing hormone for treatment of advanced prostate cancer

(2015) Ferenc G. Rick et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

SYK Is a Candidate Kinase Target for the Treatment of Advanced Prostate Cancer

(2014) V. P. S. Ghotra et al.   CANCER RESEARCH

Hooking the big one: the potential of zebrafish xenotransplantation to reform cancer drug screening in the genomic era

(2014) C. J. Veinotte et al.   Disease Models & Mechanisms

Focused chemical genomics using zebrafish xenotransplantation as a pre-clinical therapeutic platform for T-cell acute lymphoblastic leukemia

(2014) V. L. Bentley et al.   HAEMATOLOGICA

How do sex hormones modify arrhythmogenesis in long QT syndrome? Sex hormone effects on arrhythmogenic substrate and triggered activity

(2014) Katja E. Odening et al.   HEART RHYTHM

Synergistic co-targeting of prostate-specific membrane antigen and androgen receptor in prostate cancer

(2014) Jose D. Murga et al.   PROSTATE

Visnagin protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase

(2014) Y. Liu et al.   Science Translational Medicine

Synthesis and biological evaluation of prodigiosene conjugates of porphyrin, estrone and 4-hydroxytamoxifen

(2013) Cassandra L.A. Hawco et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Evaluating human cancer cell metastasis in zebrafish

(2013) Yong Teng et al.   BMC CANCER

EAU Guidelines on Prostate Cancer. Part II: Treatment of Advanced, Relapsing, and Castration-Resistant Prostate Cancer

(2013) Axel Heidenreich et al.   EUROPEAN UROLOGY

Chemotherapeutic inhibitors in the treatment of prostate cancer

(2013) Rahul R Deshmukh et al.   EXPERT OPINION ON PHARMACOTHERAPY

Molecular pathology and prostate cancer therapeutics: from biology to bedside

(2013) Daniel Nava Rodrigues et al.   JOURNAL OF PATHOLOGY

Enrichment of human prostate cancer cells with tumor initiating properties in mouse and zebrafish xenografts by differential adhesion

(2013) Nitu Bansal et al.   PROSTATE

Beyond the androgen receptor: New approaches to treating metastatic prostate cancer. Report of the 2013 Prouts Neck Prostate Cancer Meeting

(2013) Kenneth J. Pienta et al.   PROSTATE

Enzalutamide treatment in patients with metastatic castration-resistant prostate cancer progressing after chemotherapy and abiraterone acetate

(2013) Frederik Birkebaek Thomsen et al.   Scandinavian Journal of Urology

Androgen deprivation therapy: past, present and future

(2012) F. Schröder et al.   BJU INTERNATIONAL

Validation of visualized transgenic zebrafish as a high throughput model to assay bradycardia related cardio toxicity risk candidates

(2012) Dingsheng Wen et al.   JOURNAL OF APPLIED TOXICOLOGY

Sex Hormones and the QT Interval: A Review

(2012) Tara Sedlak et al.   JOURNAL OF WOMENS HEALTH

Automated Whole Animal Bio-Imaging Assay for Human Cancer Dissemination

(2012) Veerander P. S. Ghotra et al.   PLoS One

Sex-Steroid Hormones and Electrocardiographic QT-Interval Duration: Findings From the Third National Health and Nutrition Examination Survey and the Multi-Ethnic Study of Atherosclerosis

(2011) Yiyi Zhang et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Leukaemia xenotransplantation in zebrafish - chemotherapy response assay in vivo

(2011) Dale P. Corkery et al.   BRITISH JOURNAL OF HAEMATOLOGY

Re: Androgen-Deprivation Therapy in Prostate Cancer and Cardiovascular Risk: A Science Advisory From the American Heart Association, American Cancer Society, and American Urological Association: Endorsed by the American Society for Radiation Oncology

(2010) Joseph A. Smith   EUROPEAN UROLOGY

Effects of Testosterone on Ventricular Repolarization in Hypogonadic Men

(2009) Beny Charbit et al.   AMERICAN JOURNAL OF CARDIOLOGY

Are animal models predictive for humans?

(2009) Niall Shanks et al.   Philosophy Ethics and Humanities in Medicine

Transparent Adult Zebrafish as a Tool for In Vivo Transplantation Analysis

(2008) Richard Mark White et al.   Cell Stem Cell