Journal
ONCOTARGET
Volume 8, Issue 70, Pages 115774-115786Publisher
IMPACT JOURNALS LLC
DOI: 10.18632/oncotarget.22404
Keywords
next-generation metabolomics; lung cancer; precision medicine; biomarker; pathogenesis
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Lung cancer is the leading cause of cancer-related death. Next-generation metabolomics is becoming a powerful emerging technology for studying the systems biology and chemistry of health and disease. This mini review summarized the main platforms of next-generation metabolomics and its main applications in lung cancer including early diagnosis, pathogenesis, classifications and precision medicine. The period covers between 2009 and August, 2017. The major issues and future directions of metabolomics in lung cancer research and clinical applications were also discussed.
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