T cells compete by cleaving cell surface CD27 and blocking access to CD70-bearing APCs
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Title
T cells compete by cleaving cell surface CD27 and blocking access to CD70-bearing APCs
Authors
Keywords
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Journal
EUROPEAN JOURNAL OF IMMUNOLOGY
Volume 45, Issue 11, Pages 3140-3149
Publisher
Wiley
Online
2015-07-15
DOI
10.1002/eji.201545749
References
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- (2012) J. Huang et al. BLOOD
- Development of a Human Monoclonal Antibody for Potential Therapy of CD27-Expressing Lymphoma and Leukemia
- (2012) L. A. Vitale et al. CLINICAL CANCER RESEARCH
- Matrix Metalloproteinase-8 Is Overexpressed in Waldenström's Macroglobulinemia Cells, and Specific Inhibition of this Metalloproteinase Blocks Release of Soluble CD27
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- T cell vaccinology: Exploring the known unknowns
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- The Costimulatory Molecule CD27 Maintains Clonally Diverse CD8+ T Cell Responses of Low Antigen Affinity to Protect against Viral Variants
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- An alternative signal 3: CD8+ T cell memory independent of IL-12 and type I IFN is dependent on CD27/OX40 signaling
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- (2010) Robert C. Kalayjian et al. JOURNAL OF INFECTIOUS DISEASES
- Costimulatory ligand CD70 allows induction of CD8+ T-cell immunity by immature dendritic cells in a vaccination setting
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- The antigen-specific CD8+T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion
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- Chronic CD70-Driven Costimulation Impairs IgG Responses by Instructing T Cells to Inhibit Germinal Center B Cell Formation through FasL-Fas Interactions
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- Complete but curtailed T-cell response to very low-affinity antigen
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- Expression of Costimulatory Ligand CD70 on Steady-State Dendritic Cells Breaks CD8+ T Cell Tolerance and Permits Effective Immunity
- (2008) Anna M. Keller et al. IMMUNITY
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