Mechanism and timing of Mcm2–7 ring closure during DNA replication origin licensing

Review: The lord of the rings: Structure and mechanism of the sliding clamp loader

(2016) Brian A. Kelch   BIOPOLYMERS

MCM: one ring to rule them all

(2016) Tom D Deegan et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Mechanism of Archaeal MCM Helicase Recruitment to DNA Replication Origins

(2016) Rachel Y. Samson et al.   MOLECULAR CELL

Single-Molecule Studies of Origin Licensing Reveal Mechanisms Ensuring Bidirectional Helicase Loading

(2015) Simina Ticau et al.   CELL

Multi-wavelength single-molecule fluorescence analysis of transcription mechanisms

(2015) Larry J. Friedman et al.   METHODS

Structure of the eukaryotic MCM complex at 3.8 Å

(2015) Ningning Li et al.   NATURE

Regulated eukaryotic DNA replication origin firing with purified proteins

(2015) Joseph T. P. Yeeles et al.   NATURE

A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2–7 onto DNA

(2014) Stefan A. Samel et al.   GENES & DEVELOPMENT

Structural and mechanistic insights into Mcm2–7 double-hexamer assembly and function

(2014) Jingchuan Sun et al.   GENES & DEVELOPMENT

Multiple Functions for Mcm2–7 ATPase Motifs during Replication Initiation

(2014) Sukhyun Kang et al.   MOLECULAR CELL

Origin Licensing Requires ATP Binding and Hydrolysis by the MCM Replicative Helicase

(2014) Gideon Coster et al.   MOLECULAR CELL

Prereplication-complex formation: a molecular double take?

(2014) Hasan Yardimci et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An ORC/Cdc6/MCM2-7 Complex Is Formed in a Multistep Reaction to Serve as a Platform for MCM Double-Hexamer Assembly

(2013) Alejandra Fernández-Cid et al.   MOLECULAR CELL

ATPase-dependent quality control of DNA replication origin licensing

(2013) Jordi Frigola et al.   NATURE

Cryo-EM structure of a helicase loading intermediate containing ORC–Cdc6–Cdt1–MCM2-7 bound to DNA

(2013) Jingchuan Sun et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Single-molecule colocalization FRET evidence that spliceosome activation precedes stable approach of 5' splice site and branch site

(2013) D. J. Crawford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of Transcription Initiation at an Activator-Dependent Promoter Defined by Single-Molecule Observation

(2012) Larry J. Friedman et al.   CELL

ATP-dependent conformational dynamics underlie the functional asymmetry of the replicative helicase from a minimalist eukaryote

(2012) Artem Y. Lyubimov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structural basis for MCM2–7 helicase activation by GINS and Cdc45

(2011) Alessandro Costa et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A general strategy for the evolution of bond-forming enzymes using yeast display

(2011) I. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ordered and Dynamic Assembly of Single Spliceosomes

(2011) A. A. Hoskins et al.   SCIENCE

Concerted Loading of Mcm2–7 Double Hexamers around DNA during DNA Replication Origin Licensing

(2009) Dirk Remus et al.   CELL

A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication

(2009) C. Evrin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Mcm2-7 Complex Has In Vitro Helicase Activity

(2008) Matthew L. Bochman et al.   MOLECULAR CELL