Central tolerance spares the private high-avidity CD4+T-cell repertoire specific for an islet antigen in NOD mice

TCR Affinity and Tolerance Mechanisms Converge To Shape T Cell Diabetogenic Potential

(2014) Maria Bettini et al.   JOURNAL OF IMMUNOLOGY

Structural basis for self-recognition by autoimmune T-cell receptors

(2012) Yiyuan Yin et al.   IMMUNOLOGICAL REVIEWS

Thymus-specific serine protease controls autoreactive CD4 T cell development and autoimmune diabetes in mice

(2011) Christophe Viret et al.   JOURNAL OF CLINICAL INVESTIGATION

Thymus-specific serine protease contributes to the diversification of the functional endogenous CD4 T cell receptor repertoire

(2010) Christophe Viret et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Thymus-specific serine protease regulates positive selection of a subset of CD4+thymocytes

(2009) Julien Gommeaux et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla

(2008) Tom M. McCaughtry et al.   JOURNAL OF EXPERIMENTAL MEDICINE