Article
Cardiac & Cardiovascular Systems
Yuta Seko, Takao Kato, Takeshi Morimoto, Hidenori Yaku, Yasutaka Inuzuka, Yodo Tamaki, Neiko Ozasa, Masayuki Shiba, Erika Yamamoto, Yusuke Yoshikawa, Yugo Yamashita, Takeshi Kitai, Ryoji Taniguchi, Moritake Iguchi, Kazuya Nagao, Toshikazu Jinnai, Akihiro Komasa, Ryusuke Nishikawa, Yuichi Kawase, Takashi Morinaga, Mamoru Toyofuku, Yutaka Furukawa, Kenji Ando, Kazushige Kadota, Yukihito Sato, Koichiro Kuwahara, Takeshi Kimura
Summary: Elderly patients with multiple comorbidities are more likely to develop newly diagnosed infections after admission for acute heart failure, which is associated with higher in-hospital and post-discharge mortality in patients with acute heart failure.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Yuta Seko, Erika Yamamoto, Takao Kato, Takeshi Morimoto, Hidenori Yaku, Yasutaka Inuzuka, Yodo Tamaki, Neiko Ozasa, Masayuki Shiba, Yusuke Yoshikawa, Yugo Yamashita, Takeshi Kitai, Ryoji Taniguchi, Moritake Iguchi, Kazuya Nagao, Takafumi Kawai, Akihiro Komasa, Ryusuke Nishikawa, Yuichi Kawase, Takashi Morinaga, Mamoru Toyofuku, Yutaka Furukawa, Kenji Ando, Kazushige Kadota, Yukihito Sato, Koichiro Kuwahara, Takeshi Kimura
Summary: Insomnia in patients with acute heart failure (AHF) is associated with higher mortality risk and worse clinical outcomes.
Article
Cardiac & Cardiovascular Systems
Jasper Tromp, Joost C. Beusekamp, Wouter Ouwerkerk, Peter van der Meer, John G. F. Cleland, Christiane E. Angermann, Ulf Dahlstrom, Georg Ertl, Mahmoud Hassanein, Sergio Perrone, Mathieu Ghadanfar, Anja Schweizer, Achim Obergfell, Gerasimos Filippatos, Kenneth Dickstein, Sean P. Collins, Carolyn S. P. Lam
Summary: This study found differences in precipitants leading to hospitalizations for acute heart failure (AHF) on a global scale, highlighting potential regional differences in targeted prevention strategies and identifying high-risk patients for early mortality.
EUROPEAN JOURNAL OF HEART FAILURE
(2022)
Article
Cardiac & Cardiovascular Systems
Yumiko Kawakubo Ichihara, Yasuyuki Shiraishi, Shun Kohsaka, Shintaro Nakano, Yuji Nagatomo, Tomohiko Ono, Makoto Takei, Munehisa Sakamoto, Atsushi Mizuno, Mitsunobu Kitamura, Nozomi Niimi, Takashi Kohno, Tsutomu Yoshikawa
Summary: This study found that patients with behavioral precipitant factors (PFs) had a higher risk of heart failure rehospitalization, despite having a lower risk of in-hospital death.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Medicine, General & Internal
Manuel Mendez-Bailon, Rosario Iguaran-Bermudez, Francesc Formiga-Perez, Jose Carlos Arevalo Lorido, Ivan Suarez-Pedreira, Jose Luis Morales-Rull, Ana Serrado-Iglesias, Pau Llacer-Iborra, Gabriela Ormaechea-Gorricho, Francisco Javier Carrasco-Sanchez, Jesus Casado-Cerrada, Emmanuel Andres, Jesus Diez-Manglano, Noel Lorenzo-Villalba, Manuel Montero-Perez-Barquero
Summary: The study found that the PROFUND index is a good predictor of mortality in patients with acute heart failure, especially for those at intermediate to high risk. Higher scores were associated with higher mortality rates, and survival at one year decreased as the index value increased.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
M. A. ap Pfeffer, B. Claggett, E. F. Lewis, C. B. Granger, L. Kober, A. P. Maggioni, D. L. Mann, J. J. V. McMurray, J. -L. Rouleau, S. D. Solomon, P. G. Steg, O. Berwanger, M. Cikes, C. G. De Pasquale, C. East, A. Fernandez, K. Jering, U. Landmesser, R. Mehran, B. Merkely, F. Vaghaiwalla Mody, M. C. Petrie, I. Petrov, M. Schou, M. Senni, D. Sim, P. van der Meer, M. Lefkowitz, Y. Zhou, J. Gong, E. Braunwald
Summary: Among patients with acute myocardial infarction, the use of Sacubitril-Valsartan did not significantly reduce the incidence of death from cardiovascular causes or incident heart failure compared to ramipril.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Yuta Seko, Takefumi Kishimori, Takao Kato, Takeshi Morimoto, Hidenori Yaku, Yasutaka Inuzuka, Yodo Tamaki, Neiko Ozasa, Masayuki Shiba, Erika Yamamoto, Yusuke Yoshikawa, Yugo Yamashita, Takeshi Kitai, Ryoji Taniguchi, Moritake Iguchi, Kazuya Nagao, Takafumi Kawai, Akihiro Komasa, Ryusuke Nishikawa, Yuichi Kawase, Takashi Morinaga, Mamoru Toyofuku, Yutaka Furukawa, Kenji Ando, Kazushige Kadota, Yukihito Sato, Koichiro Kuwahara, Takeshi Kimura
Summary: Patients with acute heart failure who underwent coronary angiography had a lower risk of clinical outcomes and were significantly different from those who did not undergo coronary angiography.
Article
Cardiac & Cardiovascular Systems
Juan Esteban Gomez-Mesa, Clara Saldarriaga, Luis Eduardo Echeverria, Alex Rivera-Toquica, Paula Luna, Sebastian Campbell, Lisbeth Natalia Morales, Juan David Lopez Ponce De Leon, Andres Felipe Buitrago, Erika Martinez, Jorge Alberto Sandoval, Alexis Llamas, Gustavo Adolfo Moreno, Julian Vanegas, Fernan Mendoza Beltran
Summary: This study used data from the RECOLFACA registry to describe the characteristics and healthcare resource utilization patterns of HF patients in Colombia. The results showed that multiple evidence-based treatments for HF are being widely used in Colombia, but there seems to be room for improvement regarding some interventions for the treatment of patients with HF.
Article
Medicine, General & Internal
Nuri Lee, Jae Yeong Cho, Kye Hun Kim, Hyung Yoon Kim, Hyun-Jai Cho, Hae-Young Lee, Eun-Seok Jeon, Jae-Joong Kim, Myeong-Chan Cho, Shung Chull Chae, Sang Hong Baek, Seok-Min Kang, Dong-Ju Choi, Byung-Su Yoo, Byung-Hee Oh
Summary: This study aimed to evaluate the impact of cardiac troponin (TnI) on mortality in patients with acute heart failure and compare between ischemic and non-ischemic heart failure. The results showed that elevated TnI was associated with increased all-cause mortality regardless of the etiology of heart failure.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Ovidio De Filippo, Fabrizio D'Ascenzo, Wojciech Wanha, Sergio Leonardi, Sergio Raposeiras Roubin, Enrico Fabris, Alessandra Truffa Giachet, Zenon Huczek, Nicola Gaibazzi, Alfonso Ielasi, Bernardo Cortese, Andrea Borin, Ivan J. Nunez-Gil, Fabrizio Ugo, Giorgio Marengo, Matteo Bianco, Lucia Barbieri, Federico Marchini, Piotr Desperak, Maria Melendo-Viu, Claudio Montalto, Francesco Bruno, Massimo Mancone, Marcos Ferrandez-Escarabajal, Nuccia Morici, Marco Scaglione, Domenico Tuttolomondo, Mariusz Gasior, Maciej Mazurek, Gugliemo Gallone, Gianluca Campo, Wojciech Wojakowski, Emad Abu Assi, Gianfranco Sinagra, Gaetano Maria de Ferrari
Summary: Incidence of heart failure (HF) hospitalizations is significant among patients treated with percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS). Several factors including age, diabetes, chronic kidney disease, previous myocardial infarction, atrial fibrillation, pulmonary disease, GRACE risk score >=141, peripheral artery disease, and cardiogenic shock are independently associated with HF hospitalizations.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Medicine, General & Internal
Shao-dong Ye, Si-Jia Wang, Guo-Gan Wang, Lin Li, Zhi-wei Huang, Jian Qin, Chun-Sheng Li, Xue-Zhong Yu, Hong Shen, Li-Pei Yang, Yan Fu, Ya-An Zheng, Bin Zhao, Dong-Min Yu, Fu-Jun Qin, De-Gui Zhou, Ying Li, Fu-Jun Liu
Summary: This study found an association between anemia and increased risk of 1-year mortality and events in patients with acute heart failure. The association was particularly significant in subgroups such as younger age, male gender, overweight, preserved left ventricular ejection fraction, and other specified subgroups.
INTERNAL AND EMERGENCY MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Felix Arne Rottmann, Ann Katrin Breiden, Xavier Bemtgen, Thomas Welte, Alexander Supady, Tobias Wengenmayer, Dawid Leander Staudacher
Summary: Using levosimendan in heart failure patients does not significantly affect the occurrence of arrhythmias and death based on kidney function. Age and treatment methods may be more significant factors.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Yuji Nishimoto, Takao Kato, Takeshi Morimoto, Ryoji Taniguchi, Hidenori Yaku, Yasutaka Inuzuka, Yodo Tamaki, Erika Yamamoto, Yusuke Yoshikawa, Takeshi Kitai, Moritake Iguchi, Masashi Kato, Mamoru Takahashi, Toshikazu Jinnai, Tomoyuki Ikeda, Kazuya Nagao, Takafumi Kawai, Akihiro Komasa, Ryusuke Nishikawa, Yuichi Kawase, Takashi Morinaga, Kanae Su, Mitsunori Kawato, Yuta Seko, Moriaki Inoko, Mamoru Toyofuku, Yutaka Furukawa, Yoshihisa Nakagawa, Kenji Ando, Kazushige Kadota, Satoshi Shizuta, Koh Ono, Koichiro Kuwahara, Neiko Ozasa, Yukihito Sato, Takeshi Kimura
Summary: There are differences in clinical characteristics and outcomes between acute heart failure patients receiving public assistance and those not receiving public assistance. The risk of heart failure hospitalizations does not significantly differ between the two groups within 180 days after discharge, but it does significantly increase beyond 180 days.
Article
Cardiac & Cardiovascular Systems
Ryusuke Nishikawa, Takao Kato, Takeshi Morimoto, Hidenori Yaku, Yasutaka Inuzuka, Yodo Tamaki, Erika Yamamoto, Neiko Ozasa, Tomohisa Tada, Hiroki Sakamoto, Yuta Seko, Masayuki Shiba, Yusuke Yoshikawa, Yugo Yamashita, Takeshi Kitai, Ryoji Taniguchi, Moritake Iguchi, Kazuya Nagao, Takafumi Kawai, Akihiro Komasa, Yuichi Kawase, Takashi Morinaga, Mamoru Toyofuku, Yutaka Furukawa, Kenji Ando, Kazushige Kadota, Yukihito Sato, Koichiro Kuwahara, Takeshi Kimura, KCHF Study Investigators
Summary: This study analyzed the characteristics of patients who used tolvaptan and the timing of its use in patients with acute heart failure. It found that patients with tolvaptan use had higher in-hospital mortality, longer hospital stay, and higher occurrence of worsening renal failure and heart failure compared to those without tolvaptan use.
Article
Cardiac & Cardiovascular Systems
Stigi Joseph, Jeemon Panniyammakal, Jabir Abdullakutty, S. Sujithkumar, Jayaprakash L. Vaikathuseril, Johny Joseph, Shaffeq Mattummal, Eapen Punnose, Govindan Unni, Syam Natesan, Harikrishnan Sivadasanpillai
Summary: This study provides data on the baseline characteristics, guideline-directed medical therapy (GDMT) prescribing patterns, and 90-day mortality rates of patients with acute heart failure (AHF) in Kerala, India. The study found that only one-fourth of patients received GDMT and the in-hospital and 90-day mortality rates were 7% and 11.6%, respectively.
EUROPEAN HEART JOURNAL
(2022)
Article
Medicine, General & Internal
Ibrahim Al-Zakwani, Jawad Al-Lawati, Alawi A. Alsheikh-Ali, Wael Almahmeed, Wafa Rashed, Arif Al-Mulla, Mohammad Zubaid
MEDICAL PRINCIPLES AND PRACTICE
(2020)
Article
Dermatology
Ahmed Al Kamzari, Buthaina Al Musalhi, Safiya Al Abrawi, Ibrahim Al-Zakwani, Reem Abdwani
PEDIATRIC DERMATOLOGY
(2020)
Article
Public, Environmental & Occupational Health
Khalid F. Alhabib, Mohammed A. Batais, Turky H. Almigbal, Mostafa Q. Alshamiri, Hani Altaradi, Sumathy Rangarajan, Salim Yusuf
Article
Infectious Diseases
A. Balkhair, I. Al-Zakwani, M. Al Busaidi, A. Al-Khirbash, S. Al Mubaihsi, H. BaTaher, J. Al Aghbari, I. Al Busaidi, M. Al Kindi, S. Baawain, A. Al Alawi, A. Al Lawati, B. Al Rawahi, K. Al-Baimani, K. Al Zidi, N. Elfatih, B. Dawud, B. John, F. Rehman, F. Yousif, G. Al Khadouri, I. Saber, J. Lal, M. Gargouri, M. Al-Ward, N. AbuDraz, S. Al Ruqeishi, S. Kumar, W. Abdelmottaleb, Z. Al-Naamani, Z. Bin Nazar, O. Balkhair
Summary: The study evaluated the efficacy of anakinra in patients with severe COVID-19 pneumonia, showing a decreased need for mechanical ventilation, increased success in weaning off supplemental oxygen, and reduced levels of inflammatory biomarkers in patients who received anakinra.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Infectious Diseases
Florence Birru, Zaid Al-Hinai, Saif Awlad Thani, Khaloud Al-Mukhaini, Ibrahim Al-Zakwani, Raghad Al-Abdwani
Summary: This study aimed to identify risk factors and outcomes of critical pertussis in children under 13 years old. Results showed that higher white blood cell count, absolute lymphocyte count, and absolute neutrophil count were significant predictors of critical pertussis.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Multidisciplinary Sciences
Khalid F. Alhabib, Khalid Al-Rasadi, Turky H. Almigbal, Mohammed A. Batais, Ibrahim Al-Zakwani, Faisal A. Al-Allaf, Khalid Al-Waili, Fahad Zadjali, Mohammad Alghamdi, Fahad Alnouri, Zuhier Awan, Abdulhalim J. Kinsara, Ahmed AlQudaimi, Wael Almahmeed, Hani Sabbour, Mahmoud Traina, Bassam Atallah, Mohammed Al-Jarallah, Ahmad AlSarraf, Nasreen AlSayed, Haitham Amin, Hani Altaradi
Summary: This study revealed a high prevalence of FH in the Arabian Gulf region, calling for further confirmation in future population studies. Only a small proportion of patients achieved target LDL-C values, suggesting the need for healthcare policies to implement nationwide screening, raise FH awareness, and improve management strategies for FH.
Article
Clinical Neurology
Marwa Al-Senani, Abdullah Al-Salti, Ramachandiran Nandhagopal, Ibrahim Al-Zakwani, Jaber Alkhabouri, Mortadha Eltigani Elyas, Arunodaya R. Gujjar, Abdullah Al-Asmi
Summary: The prevalence of MS in the Omani population was estimated at 15.9 per 100,000, with a higher proportion of female patients than male patients. The majority of patients experienced their first clinical manifestation between the ages of 19-40.
MULTIPLE SCLEROSIS AND RELATED DISORDERS
(2021)
Article
Public, Environmental & Occupational Health
Faryal Khamis, Ziad Memish, Maher Al Bahrani, Samata Al Dowaiki, Nenad Pandak, Zakaryia Al Bolushi, Issa Al Salmi, Ibrahim Al-Zakwani
Summary: The study identified a high mortality rate among COVID-19 patients in a hospital in Oman, with factors such as advanced age, heart disease, liver disease, high ferritin levels, ARDS, sepsis, and ICU admission being associated with mortality.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2021)
Article
Peripheral Vascular Disease
Zainab Al-Tobi, Yousuf Al Suleimani, Khalid Al-Rasadi, Saud Al-Shabibi, Anwar Al Mahrizi, Juhaina Al-Maqbali, Khalid Al-Waili, Samir Al-Adawi, Ibrahim Al-Zakwani
Summary: This study evaluated the impact of olanzapine on metabolic changes in patients with psychotic disorders. The results showed that olanzapine monotherapy was associated with increased body weight, cholesterol levels, and blood pressure, as well as adverse metabolic changes. Many patients were not able to achieve their target cardiovascular treatment goals.
Article
Pharmacology & Pharmacy
Hanan Albackr, Khalid F. Alhabib, Kadhim Sulaiman, Amal Jamee, Mohamed Sobhy, Salim Benkhedda, Sobhi Dada, Ayman Hammoudeh, Habib Gamra, Ahmed Al-Motarreb, Fahad Alkindi, Mohammad Amin, Magdi G. Yousif, Hasan A. Farhan, Nadia Fellat, Wael Almahmeed, Mohammad Al Jarallah, Prashanth Panduranga, Magdy Abdelhamid, Ihab Ghaly, Dahlia Djermane, Ahcene Chibane, Hadi Skouri, Mohamad Jarrah, Hassen Amor, Nora K. Alsagheer, Mohammed A. Hozayen, Hosameldin S. Ahmed, Muhammad Ali, Anhar Ullah, Ayman Al Saleh, Faiez Zannad
Summary: Patients with acute heart failure in Arab countries have a high burden of cardiac risk factors, low income, and low education status. There is great heterogeneity in key performance indicators of acute heart failure management among Arab countries.
CURRENT VASCULAR PHARMACOLOGY
(2023)
Article
Medicine, Research & Experimental
Faryal Khamis, Salah Al Awaidy, Muna Ba'Omar, Wessam Osman, Shabnam Chhetri, Zaiyana Ambusaid, Zakariya Al Fahdi, Jaber Al Lawati, Khalsa Al Sulaimi, Salma Ali Al Bulushi, Maher Al Bahrani, Ibrahim Al-Zakwani
Summary: This study evaluated the demographic, clinical, laboratory, and all-cause mortality of moderate and severe COVID-19 patients admitted to a tertiary care hospital in Oman during the different COVID-19 waves and variant types.
Article
Pharmacology & Pharmacy
Alaa M. Soliman, Ibrahim Al-Zakwani, Ibrahim H. Younos, Shireen Al Zadjali, Mohammed Al Za'abi
Summary: This study aimed to identify and quantify potentially inappropriate prescribing (PIP) practices and related risk factors in pediatric patients. The results showed a high prevalence of PIM and PPO, indicating the need for educational and interventional activities.
Article
Pharmacology & Pharmacy
Juhaina Salim Al-Maqbali, Aqila Taqi, Samyia Al-Ajmi, Buthaina Al-Hamadani, Farhat Al-Hamadani, Fatima Bahram, Kifah Al-Balushi, Sarah Gamal, Esra Al-Lawati, Bushra Al Siyabi, Ekram Al Siyabi, Nashwa Al-Sharji, Ibrahim Al-Zakwani
Summary: Clinical pharmacists' interventions have a positive impact on both clinical and financial outcomes, enhancing treatment efficacy, avoiding drug toxicity, and achieving significant cost avoidance. Optimal documentation of interventions is crucial for highlighting the value of clinical pharmacists in multi-specialty hospitals.
Article
Pharmacology & Pharmacy
Diana Arandi Hanbali, Khamis Al Hashmi, Mohammed Al Za'abi, Ibrahim Al-Zakwani
Summary: In Oman, the use of guideline-based cardiovascular medications in heart failure patients is low, and they are often not optimally dosed at target levels.
INTERNATIONAL JOURNAL OF CLINICAL PHARMACY
(2021)