Adeno-Associated Viral Vectors Serotype 8 for Cell-Specific Delivery of Therapeutic Genes in the Central Nervous System

Adeno-Associated Virus-Based Gene Therapy for CNS Diseases

(2016) Michaël Hocquemiller et al.   HUMAN GENE THERAPY

Astrocytes: Key Regulators of Neuroinflammation

(2016) Emanuela Colombo et al.   TRENDS IN IMMUNOLOGY

Adeno-associated virus and lentivirus vectors: a refined toolkit for the central nervous system

(2016) Daniel Blessing et al.   Current Opinion in Virology

Rapid Conversion of Fibroblasts into Functional Forebrain GABAergic Interneurons by Direct Genetic Reprogramming

(2015) Gaia Colasante et al.   Cell Stem Cell

Disease-modifying strategies for Parkinson's disease

(2015) Lorraine V. Kalia et al.   MOVEMENT DISORDERS

Comparative analyses of adeno-associated viral vector serotypes 1, 2, 5, 8 and 9 in marmoset, mouse and macaque cerebral cortex

(2015) Akiya Watakabe et al.   NEUROSCIENCE RESEARCH

SOX2 Reprograms Resident Astrocytes into Neural Progenitors in the Adult Brain

(2015) Wenze Niu et al.   Stem Cell Reports

MicroRNA-Mediated In Vitro and In Vivo Direct Conversion of Astrocytes to Neuroblasts

(2015) Maryam Ghasemi-Kasman et al.   PLoS One

An anterograde rabies virus vector for high-resolution large-scale reconstruction of 3D neuron morphology

(2014) Matthias Georg Haberl et al.   Brain Structure & Function

Gene Therapy for the Nervous System: Challenges and New Strategies

(2014) Casey A. Maguire et al.   Neurotherapeutics

Temporal identity transition from Purkinje cell progenitors to GABAergic interneuron progenitors in the cerebellum

(2014) Yusuke Seto et al.   Nature Communications

Systemic gene delivery to the central nervous system using Adeno-associated virus

(2014) Mathieu Bourdenx et al.   Frontiers in Molecular Neuroscience

Direct and Retrograde Transduction of Nigral Neurons with AAV6, 8, and 9 and Intraneuronal Persistence of Viral Particles

(2013) Karin Löw et al.   HUMAN GENE THERAPY

In vivo reprogramming of astrocytes to neuroblasts in the adult brain

(2013) Wenze Niu et al.   NATURE CELL BIOLOGY

Analysis of Transduction Efficiency, Tropism and Axonal Transport of AAV Serotypes 1, 2, 5, 6, 8 and 9 in the Mouse Brain

(2013) Dominik F. Aschauer et al.   PLoS One

Parkinson's Disease: Gene Therapies

(2013) P. G. Coune et al.   Cold Spring Harbor Perspectives in Medicine

Axonal transport of adeno-associated viral vectors is serotype-dependent

(2012) E A Salegio et al.   GENE THERAPY

Galectin-3 Is Required for Resident Microglia Activation and Proliferation in Response to Ischemic Injury

(2012) M. Lalancette-Hebert et al.   JOURNAL OF NEUROSCIENCE

Advancing neurotrophic factors as treatments for age-related neurodegenerative diseases: developing and demonstrating “clinical proof-of-concept” for AAV-neurturin (CERE-120) in Parkinson's disease

(2012) Raymond T. Bartus et al.   NEUROBIOLOGY OF AGING

Optimizing Promoters for Recombinant Adeno-Associated Virus-Mediated Gene Expression in the Peripheral and Central Nervous System Using Self-Complementary Vectors

(2011) Steven J. Gray et al.   HUMAN GENE THERAPY

Direct generation of functional dopaminergic neurons from mouse and human fibroblasts

(2011) Massimiliano Caiazzo et al.   NATURE

Local and retrograde gene transfer into primate neuronal pathways via adeno-associated virus serotype 8 and 9

(2011) Y. Masamizu et al.   NEUROSCIENCE

Efficient gene transfer into neurons in monkey brain by adeno-associated virus 8

(2010) Yoshito Masamizu et al.   NEUROREPORT

High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency

(2009) E Ayuso et al.   GENE THERAPY

Ultrastructure of the subventricular zone inMacaca fascicularisand evidence of a mouse-like migratory stream

(2009) Sara Gil-Perotin et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Adeno-associated virus-mediated gene delivery approaches for the treatment of CNS disorders

(2008) Dimitra Terzi et al.   Biotechnology Journal

GFAPpromoter elements required for region-specific and astrocyte-specific expression

(2008) Youngjin Lee et al.   GLIA

AAV8, 9, Rh10, Rh43 Vector Gene Transfer in the Rat Brain: Effects of Serotype, Promoter and Purification Method

(2007) Ronald L Klein et al.   MOLECULAR THERAPY