THERAPY OF ENDOCRINE DISEASE: Steroidogenesis enzyme inhibitors in Cushing's syndrome

Ketoconazole as an Adrenal Steroidogenesis Inhibitor: Effectiveness and Risks in the Treatment of Cushing's Disease

(2014) John Newell-Price   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Next Generation Medical Therapy for Cushing's Syndrome—Can We Measure a Benefit?

(2014) Peter J. Trainer   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Ketoconazole in Cushing's Disease: Is It Worth a Try?

(2014) Frederic Castinetti et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Morphofunctional effects of mitotane on mitochondria in human adrenocortical cancer cells

(2013) Giada Poli et al.   ENDOCRINE-RELATED CANCER

LCI699, a Potent 11β-hydroxylase Inhibitor, Normalizes Urinary Cortisol in Patients With Cushing's Disease: Results From a Multicenter, Proof-of-Concept Study

(2013) Xavier Bertagna et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The use of mass spectrometry to improve the diagnosis and the management of the HPA axis

(2013) Phillip J. Monaghan et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Adrenal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2012) A. Berruti et al.   ANNALS OF ONCOLOGY

A reappraisal of the medical therapy with steroidogenesis inhibitors in Cushing's syndrome

(2012) Elena Valassi et al.   CLINICAL ENDOCRINOLOGY

Efficiency and tolerance of mitotane in Cushing's disease in 76 patients from a single center

(2012) Camille Baudry et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Etomidate in the emergency management of hypercortisolemia

(2012) Lip Min Soh et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

THERAPY IN ENDOCRINE DISEASE: Etomidate in the management of hypercortisolaemia in Cushing's syndrome: a review

(2012) Veronica A Preda et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Con: Etomidate—The Ideal Induction Agent for a Cardiac Anesthetic?

(2012) Anita K. Malhotra   JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA

Pro: Etomidate Is the Ideal Induction Agent for a Cardiac Anesthetic

(2012) Arne O. Budde et al.   JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA

Mifepristone, a Glucocorticoid Receptor Antagonist, Produces Clinical and Metabolic Benefits in Patients with Cushing's Syndrome

(2012) Maria Fleseriu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mitotane Therapy in Adrenocortical Cancer Induces CYP3A4 and Inhibits 5α-Reductase, Explaining the Need for Personalized Glucocorticoid and Androgen Replacement

(2012) Vasileios Chortis et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Study of Aldosterone Synthase Inhibition as an Add-On Therapy in Resistant Hypertension

(2012) Adam D. Karns et al.   Journal of Clinical Hypertension

The Effects of Aldosterone Synthase Inhibition on Aldosterone and Cortisol in Patients With Hypertension: A Phase II, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study

(2012) Karl Andersen et al.   Journal of Clinical Hypertension

A 12-Month Phase 3 Study of Pasireotide in Cushing's Disease

(2012) Annamaria Colao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical and Molecular Pharmacology of Etomidate

(2011) Stuart A. Forman   ANESTHESIOLOGY

Pregnancy-induced Cushing’s syndrome in recurrent pregnancies: Case report and literature review

(2011) Naomi ACHONG et al.   AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY

Adrenal disease in pregnancy

(2011) Oksana Lekarev et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Effects of a Novel Aldosterone Synthase Inhibitor for Treatment of Primary Hypertension

(2011) David A. Calhoun et al.   CIRCULATION

Drug interactions with mitotane by induction of CYP3A4 metabolism in the clinical management of adrenocortical carcinoma

(2011) Matthias Kroiss et al.   CLINICAL ENDOCRINOLOGY

High-dose mitotane strategy in adrenocortical carcinoma: prospective analysis of plasma mitotane measurement during the first 3 months of follow-up

(2011) Sophie Mauclère-Denost et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Use of Intravenous Etomidate to Control Acute Psychosis Induced by the Hypercortisolaemia in Severe Paediatric Cushing’s Disease

(2011) L.F. Chan et al.   Hormone Research in Paediatrics

Plasma Concentrations of o,p′DDD, o,p′DDA, and o,p′DDE as Predictors of Tumor Response to Mitotane in Adrenocortical Carcinoma: Results of a Retrospective ENS@T Multicenter Study

(2011) Ilse G. Hermsen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mitotane, Metyrapone, and Ketoconazole Combination Therapy as an Alternative to Rescue Adrenalectomy for Severe ACTH-Dependent Cushing's Syndrome

(2011) Peter Kamenický et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Type 2 diabetes identified in pregnancy secondary to Cushing's syndrome

(2011) R. Schiemer et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Comparison of serum cortisol measurement by immunoassay and liquid chromatography-tandem mass spectrometry in patients receiving the 11 -hydroxylase inhibitor metyrapone

(2011) P. J. Monaghan et al.   ANNALS OF CLINICAL BIOCHEMISTRY

Clinical features and management of ectopic ACTH syndrome at a single institute in Japan

(2010) Masaru Doi et al.   ENDOCRINE JOURNAL

Ketoconazole enantiomer for the treatment of diabetes mellitus

(2010) Richard Arakaki et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Successful outcome of pregnancy in a patient with Cushing's disease under treatment with ketoconazole during the first trimester of gestation

(2010) Mauro Boronat et al.   GYNECOLOGICAL ENDOCRINOLOGY

Aldosterone Synthase Inhibition With LCI699

(2010) Laurence Amar et al.   HYPERTENSION

HORMONAL AND ELECTROLYTE RESPONSES TO THE ALDOSTERONE SYNTHASE INHIBITOR LCI699 IN SODIUM DEPLETED HEALTHY SUBJECTS

(2010) Joël Menard et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cortisol measurement in patients receiving metyrapone therapy

(2010) L. J. Owen et al.   ANNALS OF CLINICAL BIOCHEMISTRY

Assessment of serum-free cortisol levels in patients with adrenocortical carcinoma treated with mitotane: a pilot study

(2009) Krystallenia I. Alexandraki et al.   CLINICAL ENDOCRINOLOGY

Transfer of Metyrapone and Its Metabolite, rac-Metyrapol, Into Breast Milk

(2009) Neil J. Hotham et al.   JOURNAL OF HUMAN LACTATION

Etomidate Infusion in the Critical Care Setting for Suppressing the Acute Phase of Cushing’s Syndrome

(2008) Ali Dabbagh et al.   ANESTHESIA AND ANALGESIA

Safety Profile and Metabolic Effects of 14 Days of Treatment with DIO-902: Results of a Phase IIa Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Trial in Patients with Type 2 Diabetes Mellitus

(2008) S SCHWARTZ et al.   CLINICAL THERAPEUTICS

Prospective evaluation of mitotane toxicity in adrenocortical cancer patients treated adjuvantly

(2008) F. Daffara et al.   ENDOCRINE-RELATED CANCER

Ketoconazole revisited: a preoperative or postoperative treatment in Cushing's disease

(2008) F Castinetti et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Preoperative management of Cushing's syndrome with metyrapone for severe psychiatric disturbances

(2008) Daisuke Obinata et al.   INTERNATIONAL JOURNAL OF UROLOGY

Treatment of Adrenocorticotropin-Dependent Cushing’s Syndrome: A Consensus Statement

(2008) B. M. K. Biller et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Reduction in Salivary Cortisol Concentration Correlates with Resolution of Psychosis in Cushing's Syndrome

(2008) P. C. Myhill et al.   JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES