Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen

High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission

(2016) David M. Plouffe et al.   Cell Host & Microbe

Combination therapies for malaria are failing—what next?

(2016) David Saunders et al.   LANCET INFECTIOUS DISEASES

Dihydroartemisinin–piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study

(2016) Chanaki Amaratunga et al.   LANCET INFECTIOUS DISEASES

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling

(2016) Amélie Le Bihan et al.   PLOS MEDICINE

In VitroActivities of Primaquine-Schizonticide Combinations on Asexual Blood Stages and Gametocytes of Plasmodium falciparum

(2015) Mynthia Cabrera et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Imaging-Based High-Throughput Screening Assay To Identify New Molecules with Transmission-Blocking Potential against Plasmodium falciparum Female Gamete Formation

(2015) Celia Miguel-Blanco et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A novel multiple-stage antimalarial agent that inhibits protein synthesis

(2015) Beatriz Baragaña et al.   NATURE

Artemisinin-resistant Plasmodium falciparum clinical isolates can infect diverse mosquito vectors of Southeast Asia and Africa

(2015) Brandyce St. Laurent et al.   Nature Communications

A New Set of Chemical Starting Points with Plasmodium falciparum Transmission-Blocking Potential for Antimalarial Drug Discovery

(2015) Maria Jesus Almela et al.   PLoS One

Multicolor Bioluminescence Boosts Malaria Research: Quantitative Dual-Color Assay and Single-Cell Imaging in Plasmodium falciparum Parasites

(2014) Luca Cevenini et al.   ANALYTICAL CHEMISTRY

A Male and Female Gametocyte Functional Viability Assay To Identify Biologically Relevant Malaria Transmission-Blocking Drugs

(2014) A. Ruecker et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Seeding Collaborations to Advance Kinase Science with the GSK Published Kinase Inhibitor Set (PKIS)

(2014) David Drewry et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria

(2014) Nicholas J White et al.   MALARIA JOURNAL

Primaquine: the risks and the benefits

(2014) Elizabeth A Ashley et al.   MALARIA JOURNAL

Male and Female Plasmodium falciparum Mature Gametocytes Show Different Responses to Antimalarial Drugs

(2013) Michael J. Delves et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Plasmodium falciparum screening assay for anti-gametocyte drugs based on parasite lactate dehydrogenase detection

(2013) Sarah D'Alessandro et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Identification of inhibitors of Plasmodium falciparum gametocyte development

(2013) Sandra Duffy et al.   MALARIA JOURNAL

A quantitative high throughput assay for identifying gametocytocidal compounds

(2013) Takeshi Q. Tanaka et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

A New In Vivo Screening Paradigm to Accelerate Antimalarial Drug Discovery

(2013) María Belén Jiménez-Díaz et al.   PLoS One

Primaquine to prevent transmission of falciparum malaria

(2012) Nicholas J White   LANCET INFECTIOUS DISEASES

Activity of Clinically Relevant Antimalarial Drugs on Plasmodium falciparum Mature Gametocytes in an ATP Bioluminescence “Transmission Blocking” Assay

(2012) Joël Lelièvre et al.   PLoS One

An Invitation to Open Innovation in Malaria Drug Discovery: 47 Quality Starting Points from the TCAMS

(2011) Félix Calderón et al.   ACS Medicinal Chemistry Letters

Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falciparum

(2011) Lev Solyakov et al.   Nature Communications

A Research Agenda to Underpin Malaria Eradication

(2011) Pedro L. Alonso et al.   PLOS MEDICINE

Thousands of chemical starting points for antimalarial lead identification

(2010) Francisco-Javier Gamo et al.   NATURE

Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials

(2008) Lucy C Okell et al.   MALARIA JOURNAL

Genome-Wide Detection of Serpentine Receptor-Like Proteins in Malaria Parasites

(2008) Luciana Madeira et al.   PLoS One

A Murine Model of falciparum-Malaria by In Vivo Selection of Competent Strains in Non-Myelodepleted Mice Engrafted with Human Erythrocytes

(2008) Iñigo Angulo-Barturen et al.   PLoS One