Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening

Voltage-Dependent Gating: Novel Insights from KCNQ1 Channels

(2016) Jianmin Cui   BIOPHYSICAL JOURNAL

KCNE1 and KCNE3: The yin and yang of voltage-gated K+ channel regulation

(2016) Geoffrey W. Abbott   GENE

Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution

(2016) Jianping Wu et al.   NATURE

Unnatural amino acid photo-crosslinking of the IKs channel complex demonstrates a KCNE1:KCNQ1 stoichiometry of up to 4:4

(2016) Christopher I Murray et al.   eLife

Steric hindrance between S4 and S5 of the KCNQ1/KCNE1 channel hampers pore opening

(2014) Koichi Nakajo et al.   Nature Communications

KCNE1 divides the voltage sensor movement in KCNQ1/KCNE1 channels into two steps

(2014) Rene Barro-Soria et al.   Nature Communications

Domain–domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channel

(2014) Mark A Zaydman et al.   eLife

Dysfunctional potassium channel subunit interaction as a novel mechanism of long QT syndrome

(2013) Michael Hoosien et al.   HEART RHYTHM

Kv7.1 ion channels require a lipid to couple voltage sensing to pore opening

(2013) M. A. Zaydman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-channel basis for the slow activation of the repolarizing cardiac potassium current,IKs

(2013) Daniel Werry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular ATP binding is required to activate the slowly activating K+ channel IKs

(2013) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intermediate state trapping of a voltage sensor

(2012) Jérôme J. Lacroix et al.   JOURNAL OF GENERAL PHYSIOLOGY

Thermodynamics of electromechanical coupling in voltage-gated ion channels

(2012) Sandipan Chowdhury et al.   JOURNAL OF GENERAL PHYSIOLOGY

Allosteric Features of KCNQ1 Gating Revealed by Alanine Scanning Mutagenesis

(2011) Li-Juan Ma et al.   BIOPHYSICAL JOURNAL

Extracellular Potassium Inhibits Kv7.1 Potassium Channels by Stabilizing an Inactivated State

(2011) Anders Peter Larsen et al.   BIOPHYSICAL JOURNAL

Mode shift of the voltage sensors in Shaker K+channels is caused by energetic coupling to the pore domain

(2011) Georges A. Haddad et al.   JOURNAL OF GENERAL PHYSIOLOGY

KCNE1 Remodels the Voltage Sensor of Kv7.1 to Modulate Channel Function

(2010) Dick Wu et al.   BIOPHYSICAL JOURNAL

State-dependent electrostatic interactions of S4 arginines with E1 in S2 during Kv7.1 activation

(2010) Dick Wu et al.   JOURNAL OF GENERAL PHYSIOLOGY

KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate

(2010) J. D. Osteen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Gating Charge Transfer Center in Voltage Sensors

(2010) X. Tao et al.   SCIENCE

A multiscale model linking ion-channel molecular dynamics and electrostatics to the cardiac action potential

(2009) J. R. Silva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kv7 (KCNQ) potassium channels that are mutated in human diseases

(2008) David A. Brown   JOURNAL OF PHYSIOLOGY-LONDON

Mechanisms by which atrial fibrillation-associated mutations in the S1 domain of KCNQ1 slow deactivation of IKs channels

(2008) Lioara Restier et al.   JOURNAL OF PHYSIOLOGY-LONDON

Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus

(2008) Kazuki Yasuda et al.   NATURE GENETICS

SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations

(2008) Hiroyuki Unoki et al.   NATURE GENETICS