Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25

New adenovirus-based vaccine vectors targeting Pfs25 elicit antibodies that inhibit Plasmodium falciparum transmission

(2017) Kathleen A. McGuire et al.   MALARIA JOURNAL

Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies

(2016) Bryan Briney et al.   CELL

An inter-laboratory comparison of standard membrane-feeding assays for evaluation of malaria transmission-blocking vaccines

(2016) Kazutoyo Miura et al.   MALARIA JOURNAL

Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice

(2016) D. Sok et al.   SCIENCE

Transmission-blocking activity is determined by transmission-reducing activity and number of control oocysts in Plasmodium falciparum standard membrane-feeding assay

(2016) Kazutoyo Miura et al.   VACCINE

Safety and Immunogenicity of Pfs25-EPA/Alhydrogel®, a Transmission Blocking Vaccine against Plasmodium falciparum: An Open Label Study in Malaria Naïve Adults

(2016) Kawsar R. Talaat et al.   PLoS One

Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes

(2015) Steven W. de Taeye et al.   CELL

Toward the development of effective transmission-blocking vaccines for malaria

(2015) Daria Nikolaeva et al.   Expert Review of Vaccines

Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection

(2015) Hadi M Yassine et al.   NATURE MEDICINE

Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity

(2015) Kwinten Sliepen et al.   Retrovirology

Transmission blocking malaria vaccines: Assays and candidates in clinical development

(2015) R.W. Sauerwein et al.   VACCINE

Comparative Assessment of Transmission-Blocking Vaccine Candidates against Plasmodium falciparum

(2015) M. C. Kapulu et al.   Scientific Reports

High-throughput sequencing of natively paired antibody chains provides evidence for original antigenic sin shaping the antibody response to influenza vaccination

(2014) Yann-Chong Tan et al.   CLINICAL IMMUNOLOGY

Proof of principle for epitope-focused vaccine design

(2014) Bruno E. Correia et al.   NATURE

Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery

(2014) E-Chiang Lee et al.   NATURE BIOTECHNOLOGY

A multi-stage malaria vaccine candidate targeting both transmission and asexual parasite life-cycle stages

(2014) Michael Theisen et al.   VACCINE

Development of a transmission-blocking malaria vaccine: Progress, challenges, and the path forward

(2014) Julia K. Nunes et al.   VACCINE

Barcode-Enabled Sequencing of Plasmablast Antibody Repertoires in Rheumatoid Arthritis

(2014) Yann-Chong Tan et al.   Arthritis & Rheumatology

Functional Comparison of Plasmodium falciparum Transmission-Blocking Vaccine Candidates by the Standard Membrane-Feeding Assay

(2013) Kazutoyo Miura et al.   INFECTION AND IMMUNITY

Qualification of Standard Membrane-Feeding Assay with Plasmodium falciparum Malaria and Potential Improvements for Future Assays

(2013) Kazutoyo Miura et al.   PLoS One

A Plant-Produced Pfs25 VLP Malaria Vaccine Candidate Induces Persistent Transmission Blocking Antibodies against Plasmodium falciparum in Immunized Mice

(2013) R. Mark Jones et al.   PLoS One

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

(2013) J. S. McLellan et al.   SCIENCE

Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

(2013) J. Jardine et al.   SCIENCE

Development of a Pfs25-EPA malaria transmission blocking vaccine as a chemically conjugated nanoparticle

(2013) Richard L. Shimp et al.   VACCINE

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

Antibodies to plant-producedPlasmodium falciparumsexual stage protein Pfs25 exhibit transmission blocking activity

(2011) Christine E. Farrance et al.   Human vaccines & immunotherapeutics

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The IC50 of anti-Pfs25 antibody in membrane-feeding assay varies among species

(2010) Lediya Cheru et al.   VACCINE

A Potent Malaria Transmission Blocking Vaccine Based on Codon Harmonized Full Length Pfs48/45 Expressed in Escherichia coli

(2009) Debabani Roy Chowdhury et al.   PLoS One

Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire

(2009) J. Glanville et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phase 1 Trial of Malaria Transmission Blocking Vaccine Candidates Pfs25 and Pvs25 Formulated with Montanide ISA 51

(2008) Yimin Wu et al.   PLoS One