A chemical chaperone improves muscle function in mice with a RyR1 mutation

Congenital myopathies

(2016) Heinz Jungbluth et al.   CURRENT OPINION IN NEUROLOGY

Role of Mitofusin-2 in mitochondrial localization and calcium uptake in skeletal muscle

(2015) Alina Ainbinder et al.   CELL CALCIUM

Ca2+Binding/Permeation via Calcium Channel, CaV1.1, Regulates the Intracellular Distribution of the Fatty Acid Transport Protein, CD36, and Fatty Acid Metabolism

(2015) Dimitra K. Georgiou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ca2+ permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca2+ signaling to sustain muscle function

(2015) Chang Lee et al.   Skeletal Muscle

New functions of mitochondria associated membranes in cellular signaling

(2014) Alexander R. van Vliet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Calcium trafficking integrates endoplasmic reticulum function with mitochondrial bioenergetics

(2014) Randal J. Kaufman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ligands for FKBP12 Increase Ca2+Influx and Protein Synthesis to Improve Skeletal Muscle Function

(2014) Chang Seok Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antioxidant treatments do not improve force recovery after fatiguing stimulation of mouse skeletal muscle fibres

(2014) Arthur J. Cheng et al.   JOURNAL OF PHYSIOLOGY-LONDON

Triadin regulation of the ryanodine receptor complex

(2014) Isabelle Marty   JOURNAL OF PHYSIOLOGY-LONDON

A Molecular Web: Endoplasmic Reticulum Stress, Inflammation, and Oxidative Stress

(2014) Namrata Chaudhari et al.   Frontiers in Cellular Neuroscience

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Post-natal heart adaptation in a knock-in mouse model of calsequestrin 2-linked recessive catecholaminergic polymorphic ventricular tachycardia

(2013) Giorgia Valle et al.   EXPERIMENTAL CELL RESEARCH

Interactions between sarco-endoplasmic reticulum and mitochondria in cardiac and skeletal muscle - pivotal roles in Ca2+ and reactive oxygen species signaling

(2013) V. Eisner et al.   JOURNAL OF CELL SCIENCE

Signal integration by mTORC1 coordinates nutrient input with biosynthetic output

(2013) Christian C. Dibble et al.   NATURE CELL BIOLOGY

Congenital myopathies – Clinical features and frequency of individual subtypes diagnosed over a 5-year period in the United Kingdom

(2013) L. Maggi et al.   NEUROMUSCULAR DISORDERS

Where the endoplasmic reticulum and the mitochondrion tie the knot: The mitochondria-associated membrane (MAM)

(2012) Arun Raturi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ablation of junctin or triadin is associated with increased cardiac injury following ischaemia/reperfusion

(2012) Wen-Feng Cai et al.   CARDIOVASCULAR RESEARCH

Measuring Protein Synthesis With SUnSET

(2012) Craig A. Goodman et al.   EXERCISE AND SPORT SCIENCES REVIEWS

AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation

(2012) Johanna T Lanner et al.   NATURE MEDICINE

Differential impact of mitochondrial positioning on mitochondrial Ca2+ uptake and Ca2+ spark suppression in skeletal muscle

(2011) Ann E. Rossi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Phenylbutyrate Up-regulates the DJ-1 Protein and Protects Neurons in Cell Culture and in Animal Models of Parkinson Disease

(2011) Wenbo Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The I4895T mutation in the type 1 ryanodine receptor induces fiber-type specific alterations in skeletal muscle that mimic premature aging

(2010) Simona Boncompagni et al.   AGING CELL

RYR1 mutations are a common cause of congenital myopathies with central nuclei

(2010) J.M. Wilmshurst et al.   ANNALS OF NEUROLOGY

de novo RYR1 heterozygous mutation (I4898T) causing lethal core–rod myopathy in twins

(2010) Aurelio Hernandez-Lain et al.   European Journal of Medical Genetics

Recessive mutations in RYR1 are a common cause of congenital fiber type disproportion

(2010) Nigel F. Clarke et al.   HUMAN MUTATION

IP3-dependent, post-tetanic calcium transients induced by electrostimulation of adult skeletal muscle fibers

(2010) Mariana Casas et al.   JOURNAL OF GENERAL PHYSIOLOGY

Muscle weakness inRyr1I4895T/WTknock-in mice as a result of reduced ryanodine receptor Ca2+ion permeation and release from the sarcoplasmic reticulum

(2010) Ryan E. Loy et al.   JOURNAL OF GENERAL PHYSIOLOGY

Sarcoplasmic reticulum–mitochondrial through-space coupling in skeletal muscleThis paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.

(2009) Robert T. Dirksen   Applied Physiology Nutrition and Metabolism

SR/ER–mitochondrial local communication: Calcium and ROS

(2009) György Csordás et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Junctin and triadin each activate skeletal ryanodine receptors but junctin alone mediates functional interactions with calsequestrin

(2009) Lan Wei et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

SUnSET, a nonradioactive method to monitor protein synthesis

(2009) Enrico K Schmidt et al.   NATURE METHODS

RyR1 S-Nitrosylation Underlies Environmental Heat Stroke and Sudden Death in Y522S RyR1 Knockin Mice

(2008) William J. Durham et al.   CELL

Increased mitochondrial Ca 2+ and decreased sarcoplasmic reticulum Ca 2+ in mitochondrial myopathy

(2008) Jan Aydin et al.   HUMAN MOLECULAR GENETICS

‘Pressure-flow‘-triggered intracellular Ca2+transients in rat cardiac myocytes: possible mechanisms and role of mitochondria

(2008) Stephen Belmonte et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mitochondria Are Linked to Calcium Stores in Striated Muscle by Developmentally Regulated Tethering Structures

(2008) Simona Boncompagni et al.   MOLECULAR BIOLOGY OF THE CELL

Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis

(2008) P Pinton et al.   ONCOGENE