Modular fluorescence complementation sensors for live cell detection of epigenetic signals at endogenous genomic sites

Live visualization of genomic loci with BiFC-TALE

(2017) Huan Hu et al.   Scientific Reports

Three-Fragment Fluorescence Complementation Coupled with Photoactivated Localization Microscopy for Nanoscale Imaging of Ternary Complexes

(2016) Minghai Chen et al.   ACS Nano

The 3D Genome as Moderator of Chromosomal Communication

(2016) Job Dekker et al.   CELL

Unravelling the complex mechanisms of transgenerational epigenetic inheritance

(2016) Georgina ET Blake et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A Genetically Encoded Probe for Live-Cell Imaging of H4K20 Monomethylation

(2016) Yuko Sato et al.   JOURNAL OF MOLECULAR BIOLOGY

Quantitative assessment of fluorescent proteins

(2016) Paula J Cranfill et al.   NATURE METHODS

Life and death rest on a bivalent chromatin state

(2016) X William Yang   NATURE NEUROSCIENCE

The molecular hallmarks of epigenetic control

(2016) C. David Allis et al.   NATURE REVIEWS GENETICS

Epigenome Editing: State of the Art, Concepts, and Perspectives

(2016) Goran Kungulovski et al.   TRENDS IN GENETICS

Maintenance of Epigenetic Information

(2016) Geneviève Almouzni et al.   Cold Spring Harbor Perspectives in Biology

Tracing Dynamic Changes of DNA Methylation at Single-Cell Resolution

(2015) Yonatan Stelzer et al.   CELL

Visualizing posttranslational and epigenetic modifications of endogenous proteins in vivo

(2015) Hiroshi Kimura et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Crystal Structure of Human DNA Methyltransferase 1

(2015) Zhi-Min Zhang et al.   JOURNAL OF MOLECULAR BIOLOGY

Single molecule and single cell epigenomics

(2015) Byung-Ryool Hyun et al.   METHODS

Multicolor CRISPR labeling of chromosomal loci in human cells

(2015) Hanhui Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Constitutive heterochromatin formation and transcription in mammals

(2015) Nehmé Saksouk et al.   Epigenetics & Chromatin

Affinity reagents for studying histone modifications & guidelines for their quality control

(2015) Goran Kungulovski et al.   Epigenomics

An infrared reporter to detect spatiotemporal dynamics of protein-protein interactions

(2014) Emmanuelle Tchekanda et al.   NATURE METHODS

Targeting non-coding RNAs with the CRISPR/Cas9 system in human cell lines

(2014) Tsui-Ting Ho et al.   NUCLEIC ACIDS RESEARCH

Significant reduction of BiFC non-specific assembly facilitatesin plantaassessment of heterotrimeric G-protein interactors

(2014) Timothy E. Gookin et al.   PLANT JOURNAL

Heterochromatin Dynamics during the Differentiation Process Revealed by the DNA Methylation Reporter Mouse, MethylRO

(2014) Jun Ueda et al.   Stem Cell Reports

Detection of histone modifications at specific gene loci in single cells in histological sections

(2013) Delphine Gomez et al.   NATURE METHODS

DNA methylation: roles in mammalian development

(2013) Zachary D. Smith et al.   NATURE REVIEWS GENETICS

DNA methylation dynamics in health and disease

(2013) Yehudit Bergman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Sequence-specific microscopic visualization of DNA methylation status at satellite repeats in individual cell nuclei and chromosomes

(2013) Yufeng Li et al.   NUCLEIC ACIDS RESEARCH

Visualization of repetitive DNA sequences in human chromosomes with transcription activator-like effectors

(2013) H. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetically encoded system to track histone modification in vivo

(2013) Yuko Sato et al.   Scientific Reports

An Optimized microRNA Backbone for Effective Single-Copy RNAi

(2013) Christof Fellmann et al.   Cell Reports

Visualization of cofilin-actin and Ras-Raf interactions by bimolecular fluorescence complementation assays using a new pair of split Venus fragments

(2012) Kazumasa Ohashi et al.   BIOTECHNIQUES

Bimolecular fluorescence complementation (BiFC): A 5-year update and future perspectives

(2012) Yutaka Kodama et al.   BIOTECHNIQUES

DNA methyltransferase inhibitors in cancer: a chemical and therapeutic patent overview and selected clinical studies

(2012) Jacques Fahy et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Improving FRET dynamic range with bright green and red fluorescent proteins

(2012) Amy J Lam et al.   NATURE METHODS

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Targeted manipulation of heterochromatin rescues MeCP2 Rett mutants and re-establishes higher order chromatin organization

(2012) Corella S. Casas-Delucchi et al.   NUCLEIC ACIDS RESEARCH

Application of Celluspots peptide arrays for the analysis of the binding specificity of epigenetic reading domains to modified histone tails

(2011) Ina Bock et al.   BMC BIOCHEMISTRY

Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin

(2011) Corella S. Casas-Delucchi et al.   NUCLEIC ACIDS RESEARCH

DNA methylation profiling using live-cell imaging

(2010) Kazuo Yamagata   METHODS

Recruitment of MBD1 to target genes requires sequence-specific interaction of the MBD domain with methylated DNA

(2010) Thomas Clouaire et al.   NUCLEIC ACIDS RESEARCH

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

Bimolecular Fluorescence Complementation (BiFC) Analysis as a Probe of Protein Interactions in Living Cells

(2008) Tom K. Kerppola   Annual Review of Biophysics