Spatial constraints govern competition of mutant clones in human epidermis

Cell Competition: Mechanisms and Physiological Roles

(2016) Cristina Clavería et al.   Annual Review of Cell and Developmental Biology

Cell Competition Drives the Growth of Intestinal Adenomas in Drosophila

(2016) Saskia J.E. Suijkerbuijk et al.   CURRENT BIOLOGY

Mimicking the topography of the epidermal–dermal interface with elastomer substrates

(2016) Priyalakshmi Viswanathan et al.   Integrative Biology

Defining the clonal dynamics leading to mouse skin tumour initiation

(2016) Adriana Sánchez-Danés et al.   NATURE

Constrained positive selection on cancer mutations in normal skin

(2016) Iñigo Martincorena et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reply to Martincorena et al.: Evidence for constrained positive selection of cancer mutations in normal skin is lacking

(2016) Benjamin D. Simons   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Big Bang model of human colorectal tumor growth

(2015) Andrea Sottoriva et al.   NATURE GENETICS

Deep sequencing as a probe of normal stem cell fate and preneoplasia in human epidermis

(2015) Benjamin D. Simons   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High burden and pervasive positive selection of somatic mutations in normal human skin

(2015) I. Martincorena et al.   SCIENCE

Differentiation imbalance in single oesophageal progenitor cells causes clonal immortalization and field change

(2014) Maria P. Alcolea et al.   NATURE CELL BIOLOGY

Recurrent point mutations in the kinetochore gene KNSTRN in cutaneous squamous cell carcinoma

(2014) Carolyn S Lee et al.   NATURE GENETICS

Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen

(2014) Kifayathullah Liakath-Ali et al.   Nature Communications

Tissue Repair through Cell Competition and Compensatory Cellular Hypertrophy in Postmitotic Epithelia

(2013) Yoichiro Tamori et al.   DEVELOPMENTAL CELL

Mutational Landscape of Basal Cell Carcinomas by Whole-Exome Sequencing

(2013) Shyam S. Jayaraman et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Myc-driven endogenous cell competition in the early mammalian embryo

(2013) Cristina Clavería et al.   NATURE

Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution

(2013) A. Humphries et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation

(2013) C. Tomasetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lineage Tracing

(2012) Kai Kretzschmar et al.   CELL

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma

(2011) N. J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1

(2011) N. Agrawal et al.   SCIENCE

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

The Ordered Architecture of Murine Ear Epidermis Is Maintained by Progenitor Cells with Random Fate

(2010) David P. Doupé et al.   DEVELOPMENTAL CELL

Stampy: A statistical algorithm for sensitive and fast mapping of Illumina sequence reads

(2010) G. Lunter et al.   GENOME RESEARCH

Persistent competition among stem cells and their daughters in the Drosophila ovary germline niche

(2009) C. Rhiner et al.   DEVELOPMENT

Epidermal Notch signalling: differentiation, cancer and adhesion

(2008) Fiona M Watt et al.   CURRENT OPINION IN CELL BIOLOGY