SC83288 is a clinical development candidate for the treatment of severe malaria

Luciferase-Based, High-Throughput Assay for Screening and Profiling Transmission-Blocking Compounds against Plasmodium falciparum Gametocytes

(2016) Leonardo Lucantoni et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Large-scale production of Plasmodium falciparum gametocytes for malaria drug discovery

(2016) Sandra Duffy et al.   Nature Protocols

Reappraising the effects of artemisinin on the ATPase activity of PfATP6 and SERCA1a E255L expressed in Xenopus laevis oocytes

(2016) Stéphanie David-Bosne et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Reappraising the effects of artemisinin on the ATPase activity of PfATP6 and SERCA1a E255L expressed in Xenopus laevis oocytes

(2016) Stéphanie David-Bosne et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Antimalarial compounds in Phase II clinical development

(2015) Jana Held et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Artemisinin nanoformulation suitable for intravenous injection: Preparation, characterization and antimalarial activities

(2015) Nehal Ibrahim et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

PfMDR2 and PfMDR5 are dispensable for Plasmodium falciparum asexual parasite multiplication but change in vitro susceptibility to anti-malarial drugs

(2015) Maarten van der Velden et al.   MALARIA JOURNAL

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

(2015) Alassane Mbengue et al.   NATURE

A novel multiple-stage antimalarial agent that inhibits protein synthesis

(2015) Beatriz Baragaña et al.   NATURE

Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate

(2015) Shahul Hameed P. et al.   Nature Communications

Delayed haemolysis after artesunate treatment of severe malaria – Review of the literature and perspective

(2015) Thierry Rolling et al.   Travel Medicine and Infectious Disease

Haemolysis associated with the treatment of malaria with artemisinin derivatives: a systematic review of current evidence

(2014) Khalid Rehman et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

N-Aryl-2-aminobenzimidazoles: Novel, Efficacious, Antimalarial Lead Compounds

(2014) Sreekanth Ramachandran et al.   JOURNAL OF MEDICINAL CHEMISTRY

Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

(2014) Elizabeth A. Ashley et al.   NEW ENGLAND JOURNAL OF MEDICINE

(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance ofPlasmodium

(2014) María Belén Jiménez-Díaz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum

(2014) Akhil B. Vaidya et al.   Nature Communications

Identification of MMV Malaria Box Inhibitors of Plasmodium falciparum Early-Stage Gametocytes Using a Luciferase-Based High-Throughput Assay

(2013) Leonardo Lucantoni et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimalarial screening via large-scale purification ofPlasmodium falciparumCa2+-ATPase 6 andin vitrostudies

(2013) Stéphanie David-Bosne et al.   FEBS Journal

Designing the next generation of medicines for malaria control and eradication

(2013) Jeremy N Burrows et al.   MALARIA JOURNAL

Quinolone-3-Diarylethers: A New Class of Antimalarial Drug

(2013) A. Nilsen et al.   Science Translational Medicine

A tale of three next generation sequencing platforms: comparison of Ion torrent, pacific biosciences and illumina MiSeq sequencers

(2012) Michael Quail et al.   BMC GENOMICS

BamView: visualizing and interpretation of next-generation sequencing read alignments

(2012) T. Carver et al.   BRIEFINGS IN BIOINFORMATICS

Applications of minimal physiologically-based pharmacokinetic models

(2012) Yanguang Cao et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

P. falciparum In Vitro Killing Rates Allow to Discriminate between Different Antimalarial Mode-of-Action

(2012) Laura M. Sanz et al.   PLoS One

RNA helicases in infection and disease

(2012) Lenz Steimer et al.   RNA Biology

PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 3: Comparative assessement of prediction methods of human clearance

(2011) Barbara J. Ring et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria

(2011) Jane Achan et al.   MALARIA JOURNAL

From unwinding to clamping — the DEAD box RNA helicase family

(2011) Patrick Linder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RATT: Rapid Annotation Transfer Tool

(2011) Thomas D. Otto et al.   NUCLEIC ACIDS RESEARCH

Fosmidomycin Uptake into Plasmodium and Babesia-Infected Erythrocytes Is Facilitated by Parasite-Induced New Permeability Pathways

(2011) Stefan Baumeister et al.   PLoS One

Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria

(2011) S. A. Charman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology

(2010) Thomas D. Otto et al.   BIOINFORMATICS

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

A quantitative analysis of kinase inhibitor selectivity

(2008) Mazen W Karaman et al.   NATURE BIOTECHNOLOGY

A Murine Model of falciparum-Malaria by In Vivo Selection of Competent Strains in Non-Myelodepleted Mice Engrafted with Human Erythrocytes

(2008) Iñigo Angulo-Barturen et al.   PLoS One

Selection of a trioxaquine as an antimalarial drug candidate

(2008) F. Cosledan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA