Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation

Structural and Molecular Basis for Coordination in a Viral DNA Packaging Motor

(2016) Huzhang Mao et al.   Cell Reports

Architecture of the Complex Formed by Large and Small Terminase Subunits from Bacteriophage P22

(2015) Reginald McNulty et al.   JOURNAL OF MOLECULAR BIOLOGY

The scrunchworm hypothesis: Transitions between A-DNA and B-DNA provide the driving force for genome packaging in double-stranded DNA bacteriophages

(2015) Stephen C. Harvey   JOURNAL OF STRUCTURAL BIOLOGY

A Molecular Staple: D-Loops in the I Domain of Bacteriophage P22 Coat Protein Make Important Intercapsomer Contacts Required for Procapsid Assembly

(2015) Nadia G. D'Lima et al.   JOURNAL OF VIROLOGY

Structure and mechanism of the ATPase that powers viral genome packaging

(2015) Brendan J. Hilbert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nature׳s favorite building block: Deciphering folding and capsid assembly of proteins with the HK97-fold

(2015) Margaret M. Suhanovsky et al.   VIROLOGY

Cryo-EM structure of the bacteriophage T4 portal protein assembly at near-atomic resolution

(2015) Lei Sun et al.   Nature Communications

Common mechanisms of DNA translocation motors in bacteria and viruses using one-way revolution mechanism without rotation

(2014) Peixuan Guo et al.   BIOTECHNOLOGY ADVANCES

A Viral Packaging Motor Varies Its DNA Rotation and Step Size to Preserve Subunit Coordination as the Capsid Fills

(2014) Shixin Liu et al.   CELL

Highly Specific Salt Bridges Govern Bacteriophage P22 Icosahedral Capsid Assembly: Identification of the Site in Coat Protein Responsible for Interaction with Scaffolding Protein

(2014) J. R. Cortines et al.   JOURNAL OF VIROLOGY

An atomic model of brome mosaic virus using direct electron detection and real-space optimization

(2014) Zhao Wang et al.   Nature Communications

Architecture of viral genome-delivery molecular machines

(2013) Anshul Bhardwaj et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Large Terminase Conformational Change Induced by Connector Binding in Bacteriophage T7

(2013) María I. Daudén et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structures of the phage Sf6 large terminase provide new insights into DNA translocation and cleavage

(2013) H. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The C-terminal domain of the bacteriophage T4 terminase docks on the prohead portal clip region during DNA packaging

(2013) Aparna Banerjee Dixit et al.   VIROLOGY

Role of Channel Lysines and the “Push Through a One-Way Valve” Mechanism of the Viral DNA Packaging Motor

(2012) Huaming Fang et al.   BIOPHYSICAL JOURNAL

Structure of P22 Headful Packaging Nuclease

(2012) Ankoor Roy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Portal-Large Terminase Interactions of the Bacteriophage T4 DNA Packaging Machine Implicate a Molecular Lever Mechanism for Coupling ATPase to DNA Translocation

(2012) Shylaja Hegde et al.   JOURNAL OF VIROLOGY

Small Terminase Couples Viral DNA Binding to Genome-Packaging ATPase Activity

(2012) Ankoor Roy et al.   STRUCTURE

Conformational Changes in Bacteriophage P22 Scaffolding Protein Induced by Interaction with Coat Protein

(2011) G. Pauline Padilla-Meier et al.   JOURNAL OF MOLECULAR BIOLOGY

Role of φ29 Connector Channel Loops in Late-Stage DNA Packaging

(2011) Shelley Grimes et al.   JOURNAL OF MOLECULAR BIOLOGY

The DNA-packaging nanomotor of tailed bacteriophages

(2011) Sherwood R. Casjens   NATURE REVIEWS MICROBIOLOGY

Three-dimensional structure of a viral genome-delivery portal vertex

(2011) Adam S Olia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the ATP synthase catalytic complex (F1) from Escherichia coli in an autoinhibited conformation

(2011) Gino Cingolani et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis for scaffolding-mediated assembly and maturation of a dsDNA virus

(2011) D.-H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peering Down the Barrel of a Bacteriophage Portal: The Genome Packaging and Release Valve in P22

(2011) Jinghua Tang et al.   STRUCTURE

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Direct Interaction of the Bacteriophage SPP1 Packaging ATPase with the Portal Protein

(2010) Leonor Oliveira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural changes in a marine podovirus associated with release of its genome into Prochlorococcus

(2010) Xiangan Liu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

P22 Coat Protein Structures Reveal a Novel Mechanism for Capsid Maturation: Stability without Auxiliary Proteins or Chemical Crosslinks

(2010) Kristin N. Parent et al.   STRUCTURE

The Small Terminase, gp16, of Bacteriophage T4 Is a Regulator of the DNA Packaging Motor

(2009) Abdulrahman S. Al-Zahrani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inferential Optimization for Simultaneous Fitting of Multiple Components into a CryoEM Map of Their Assembly

(2009) Keren Lasker et al.   JOURNAL OF MOLECULAR BIOLOGY

The P22 Tail Machine at Subnanometer Resolution Reveals the Architecture of an Infection Conduit

(2009) Gabriel C. Lander et al.   STRUCTURE

The Bacteriophage DNA Packaging Motor

(2008) Venigalla B. Rao et al.   Annual Review of Genetics

The Structure of the Phage T4 DNA Packaging Motor Suggests a Mechanism Dependent on Electrostatic Forces

(2008) Siyang Sun et al.   CELL

Probing Conserved Helical Modules of Portal Complexes by Mass Spectrometry-based Hydrogen/Deuterium Exchange

(2008) Sebyung Kang et al.   JOURNAL OF MOLECULAR BIOLOGY

Determination of Stoichiometry and Conformational Changes in the First Step of the P22 Tail Assembly

(2008) Kristina Lorenzen et al.   JOURNAL OF MOLECULAR BIOLOGY

A Conformational Switch in Bacteriophage P22 Portal Protein Primes Genome Injection

(2008) Hongjin Zheng et al.   MOLECULAR CELL

Foldon-guided self-assembly of ultra-stable protein fibers

(2008) Anshul Bhardwaj et al.   PROTEIN SCIENCE