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Title
Endocytosis regulates TDP-43 toxicity and turnover
Authors
Keywords
-
Journal
Nature Communications
Volume 8, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-12-07
DOI
10.1038/s41467-017-02017-x
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Note: Only part of the references are listed.- Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice
- (2017) Lindsay A. Becker et al. NATURE
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- (2017) Alyssa N. Coyne et al. Cell Reports
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- (2016) Yohei Iguchi et al. BRAIN
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- (2016) Benjamin M Schwenk et al. EMBO JOURNAL
- Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin‐2 to induce motor neuron dysfunction and cell death
- (2016) Chantal Sellier et al. EMBO JOURNAL
- The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy
- (2016) Christopher P Webster et al. EMBO JOURNAL
- Role of BMP receptor traffic in synaptic growth defects in an ALS model
- (2016) Mugdha Deshpande et al. MOLECULAR BIOLOGY OF THE CELL
- Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling
- (2016) Janet Ugolino et al. PLoS Genetics
- Membrane Trafficking in the Yeast Saccharomyces cerevisiae Model
- (2015) Serge Feyder et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- LC3 overexpression reduces Aβ neurotoxicity through increasing α7nAchR expression and autophagic activity in neurons and mice
- (2015) Shih-Ya Hung et al. NEUROPHARMACOLOGY
- Autophagic Recycling Plays a Central Role in Maize Nitrogen Remobilization
- (2015) Faqiang Li et al. PLANT CELL
- Alterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS?
- (2015) Anaïs Aulas et al. Frontiers in Cellular Neuroscience
- Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
- (2014) Anne Simonsen et al. Autophagy
- C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking
- (2014) Manal A. Farg et al. HUMAN MOLECULAR GENETICS
- Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species
- (2014) E. L. Scotter et al. JOURNAL OF CELL SCIENCE
- Classes of phosphoinositide 3-kinases at a glance
- (2014) S. Jean et al. JOURNAL OF CELL SCIENCE
- Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models
- (2014) Sami J Barmada et al. Nature Chemical Biology
- Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition
- (2014) A. Yu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Endocytosis and Autophagy: Exploitation or Cooperation?
- (2014) S. A. Tooze et al. Cold Spring Harbor Perspectives in Biology
- The product of C9orf72, a gene strongly implicated in neurodegeneration, is structurally related to DENN Rab-GEFs
- (2013) Timothy P. Levine et al. BIOINFORMATICS
- Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function
- (2013) J. Ross Buchan et al. CELL
- Delineating the membrane-disrupting and seeding properties of the TDP-43 amyloidogenic core
- (2013) Gerard Chun-Hao Liu et al. CHEMICAL COMMUNICATIONS
- CORVET and HOPS tethering complexes - coordinators of endosome and lysosome fusion
- (2013) H. J. k. Balderhaar et al. JOURNAL OF CELL SCIENCE
- Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models
- (2013) Hyung-Jun Kim et al. NATURE GENETICS
- State of play in amyotrophic lateral sclerosis genetics
- (2013) Alan E Renton et al. NATURE NEUROSCIENCE
- Role of Endocytosis in Localization and Maintenance of the Spatial Markers for Bud-Site Selection in Yeast
- (2013) Shanshan Tuo et al. PLoS One
- The ESCRT machinery
- (2012) Oliver Schmidt et al. CURRENT BIOLOGY
- Governance of Endocytic Trafficking and Signaling by Reversible Ubiquitylation
- (2012) Michael J. Clague et al. DEVELOPMENTAL CELL
- Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models
- (2012) Maria Armakola et al. NATURE GENETICS
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- Endogenous TDP-43 localized to stress granules can subsequently form protein aggregates
- (2012) Sarah J. Parker et al. NEUROCHEMISTRY INTERNATIONAL
- Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability
- (2012) B. Bilican et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43
- (2012) I.-F. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Wild-type and A315T mutant TDP-43 exert differential neurotoxicity in a Drosophila model of ALS
- (2011) Patricia S. Estes et al. HUMAN MOLECULAR GENETICS
- Distinct Autophagosomal-Lysosomal Fusion Mechanism Revealed by Thapsigargin-Induced Autophagy Arrest
- (2011) Ian G. Ganley et al. MOLECULAR CELL
- Role of Rab GTPases in Membrane Traffic and Cell Physiology
- (2011) Alex H. Hutagalung et al. PHYSIOLOGICAL REVIEWS
- Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
- (2010) Andrew C. Elden et al. NATURE
- Modelling neurodegeneration in Saccharomyces cerevisiae: why cook with baker's yeast?
- (2010) Vikram Khurana et al. NATURE REVIEWS NEUROSCIENCE
- Loss of ALS2/Alsin Exacerbates Motor Dysfunction in a SOD1H46R-Expressing Mouse ALS Model by Disturbing Endolysosomal Trafficking
- (2010) Shinji Hadano et al. PLoS One
- Deleterious Variants of FIG4, a Phosphoinositide Phosphatase, in Patients with ALS
- (2009) Clement Y. Chow et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Eukaryotic Stress Granules: The Ins and Outs of Translation
- (2009) J. Ross Buchan et al. MOLECULAR CELL
- Degradation of TDP-43 and its pathogenic form by autophagy and the ubiquitin-proteasome system
- (2009) Xiaoju Wang et al. NEUROSCIENCE LETTERS
- Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity
- (2009) Y.-J. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Potentiation of Amyotrophic Lateral Sclerosis (ALS)-associated TDP-43 Aggregation by the Proteasome-targeting Factor, Ubiquilin 1
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- Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG
- (2008) Eisuke Itakura et al. MOLECULAR BIOLOGY OF THE CELL
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