Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression

Unexpected high rate of early tumor recurrence in patients with HCV-related HCC undergoing interferon-free therapy

(2016) María Reig et al.   JOURNAL OF HEPATOLOGY

IAP antagonization promotes inflammatory destruction of vascular endothelium

(2015) A. Witt et al.   EMBO REPORTS

First-in-man Study of Western Reserve Strain Oncolytic Vaccinia Virus: Safety, Systemic Spread, and Antitumor Activity

(2015) Herbert J Zeh et al.   MOLECULAR THERAPY

Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

(2015) Stefani Spranger et al.   NATURE

First oncolytic virus approved for melanoma immunotherapy

(2015) Jonathan Pol et al.   OncoImmunology

Immunosurveillance by Antiangiogenesis: Tumor Growth Arrest by T Cell–Derived Thrombospondin-1

(2014) Keri L. Schadler et al.   CANCER RESEARCH

Re-engineering Vesicular Stomatitis Virus to Abrogate Neurotoxicity, Circumvent Humoral Immunity, and Enhance Oncolytic Potency

(2014) A. Muik et al.   CANCER RESEARCH

Internalization and TLR-dependent type I interferon production by monocytes in response to Toxoplasma gondii

(2014) Seong-Ji Han et al.   IMMUNOLOGY AND CELL BIOLOGY

Cell Cycle Control and HIV-1 Susceptibility Are Linked by CDK6-Dependent CDK2 Phosphorylation of SAMHD1 in Myeloid and Lymphoid Cells

(2014) Eduardo Pauls et al.   JOURNAL OF IMMUNOLOGY

Virus infection, antiviral immunity, and autoimmunity

(2013) Daniel R. Getts et al.   IMMUNOLOGICAL REVIEWS

Virus-induced hepatocellular carcinomas cause antigen-specific local tolerance

(2013) Gerald Willimsky et al.   JOURNAL OF CLINICAL INVESTIGATION

Comparative analysis of disease pathogenesis and molecular mechanisms of New World and Old World arenavirus infections

(2013) L. McLay et al.   JOURNAL OF GENERAL VIROLOGY

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

Innate and adaptive immune cells in the tumor microenvironment

(2013) Thomas F Gajewski et al.   NATURE IMMUNOLOGY

Arenavirus Variations Due to Host-Specific Adaptation

(2013) Juan Zapata et al.   Viruses-Basel

Usp18 Driven Enforced Viral Replication in Dendritic Cells Contributes to Break of Immunological Tolerance in Autoimmune Diabetes

(2013) Nadine Honke et al.   PLoS Pathogens

Interferon-β-armed oncolytic adenovirus induces both apoptosis and necroptosis in cancer cells

(2012) Hongling Huang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Steady-state neutrophil homeostasis is dependent on TLR4/TRIF signaling

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Potent systemic therapy of multiple myeloma utilizing oncolytic vesicular stomatitis virus coding for interferon-β

(2012) S Naik et al.   CANCER GENE THERAPY

Rapid Differentiation of Monocytes into Type I IFN-Producing Myeloid Dendritic Cells as an Antiviral Strategy against Influenza Virus Infection

(2012) W. Cao et al.   JOURNAL OF IMMUNOLOGY

Resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus: Role of type I interferon signaling

(2012) Megan Moerdyk-Schauwecker et al.   VIROLOGY

Role of Lymphocytic Choriomeningitis Virus (LCMV) in Understanding Viral Immunology: Past, Present and Future

(2012) Xin Zhou et al.   Viruses-Basel

Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus

(2011) Nadine Honke et al.   NATURE IMMUNOLOGY

RNAi screening reveals requirement for host cell secretory pathway in infection by diverse families of negative-strand RNA viruses

(2011) D. Panda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

Oncolytic measles viruses encoding interferon β and the thyroidal sodium iodide symporter gene for mesothelioma virotherapy

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Genes Determining the Course of Virus Persistence in the Liver: Lessons from Murine Infection with Lymphocytic Choriomeningitis Virus

(2010) Philipp A. Lang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice

(2010) Philipp A. Lang et al.   HEPATOLOGY

Inflammatory Monocytes but Not Neutrophils Are Necessary To Control Infection with Toxoplasma gondii in Mice

(2010) I. R. Dunay et al.   INFECTION AND IMMUNITY

Depletion of Gr-1+, but not Ly6G+, immune cells exacerbates virus replication and disease in an intranasal model of herpes simplex virus type 1 infection

(2010) M. Wojtasiak et al.   JOURNAL OF GENERAL VIROLOGY

Urokinase-Targeted Fusion by Oncolytic Sendai Virus Eradicates Orthotopic Glioblastomas by Pronounced Synergy With Interferon-β Gene

(2010) Yuzo Hasegawa et al.   MOLECULAR THERAPY

Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity

(2010) Lukas Flatz et al.   NATURE MEDICINE

Blood Monocytes: Development, Heterogeneity, and Relationship with Dendritic Cells

(2009) Cedric Auffray et al.   Annual Review of Immunology

Preclinical models of HPV+ and HPV− HNSCC in mice: An immune clearance of HPV+ HNSCC

(2009) Robin Williams et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Hematopoietic cell-derived interferon controls viral replication and virus-induced disease

(2008) P. A. Lang et al.   BLOOD

Aggravation of viral hepatitis by platelet-derived serotonin

(2008) Philipp A Lang et al.   NATURE MEDICINE

Visualization of IFN  production by plasmacytoid versus conventional dendritic cells under specific stimulation conditions in vivo

(2008) S. Scheu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Treatment of Argentine hemorrhagic fever

(2007) Delia A. Enria et al.   ANTIVIRAL RESEARCH