Super-resolution microscopy reveals functional organization of dopamine transporters into cholesterol and neuronal activity-dependent nanodomains

Optogenetic Control of Synaptic Composition and Function

(2017) Brooke L. Sinnen et al.   NEURON

Where Do We Stand with Super-Resolution Optical Microscopy?

(2016) Karin Nienhaus et al.   JOURNAL OF MOLECULAR BIOLOGY

Varying label density allows artifact-free analysis of membrane-protein nanoclusters

(2016) Florian Baumgart et al.   NATURE METHODS

Clustering and Functional Coupling of Diverse Ion Channels and Signaling Proteins Revealed by Super-resolution STORM Microscopy in Neurons

(2016) Jie Zhang et al.   NEURON

Extracting quantitative information from single-molecule super-resolution imaging data with LAMA – LocAlization Microscopy Analyzer

(2016) Sebastian Malkusch et al.   Scientific Reports

Mapping Synaptic Input Fields of Neurons with Super-Resolution Imaging

(2015) Yaron M. Sigal et al.   CELL

 -synuclein assemblies sequester neuronal  3-Na+/K+-ATPase and impair Na+ gradient

(2015) A. N. Shrivastava et al.   EMBO JOURNAL

Brain Region-Specific Trafficking of the Dopamine Transporter

(2015) E. R. Block et al.   JOURNAL OF NEUROSCIENCE

Dynamical Organization of Syntaxin-1A at the Presynaptic Active Zone

(2015) Alexander Ullrich et al.   PLoS Computational Biology

Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion

(2014) Anaël Chazeau et al.   EMBO JOURNAL

The Serotonin Transporter Undergoes Constitutive Internalization and Is Primarily Sorted to Late Endosomes and Lysosomal Degradation

(2014) Troels Rahbek-Clemmensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell-specific STORM super-resolution imaging reveals nanoscale organization of cannabinoid signaling

(2014) Barna Dudok et al.   NATURE NEUROSCIENCE

Spine neck plasticity regulates compartmentalization of synapses

(2014) Jan Tønnesen et al.   NATURE NEUROSCIENCE

Generating bursts (and pauses) in the dopamine midbrain neurons

(2014) C.A. Paladini et al.   NEUROSCIENCE

Differential targeting of the dopamine transporter to recycling or degradative pathways during amphetamine- or PKC-regulated endocytosis in dopamine neurons

(2013) Weimin C. Hong et al.   FASEB JOURNAL

Localization microscopy coming of age: from concepts to biological impact

(2013) M. Sauer   JOURNAL OF CELL SCIENCE

Super-Resolution Imaging Reveals That AMPA Receptors Inside Synapses Are Dynamically Organized in Nanodomains Regulated by PSD95

(2013) D. Nair et al.   JOURNAL OF NEUROSCIENCE

X-ray structure of dopamine transporter elucidates antidepressant mechanism

(2013) Aravind Penmatsa et al.   NATURE

Seeing the forest tree by tree: super-resolution light microscopy meets the neurosciences

(2013) Marta Maglione et al.   NATURE NEUROSCIENCE

Flotillins Regulate Membrane Mobility of the Dopamine Transporter but Are Not Required for Its Protein Kinase C Dependent Endocytosis

(2013) Tatiana Sorkina et al.   TRAFFIC

Super-resolution Imaging Reveals the Internal Architecture of Nano-sized Syntaxin Clusters

(2012) Dana Bar-On et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Importance of cholesterol in dopamine transporter function

(2012) Kymry T. Jones et al.   JOURNAL OF NEUROCHEMISTRY

The membrane raft protein Flotillin-1 is essential in dopamine neurons for amphetamine-induced behavior in Drosophila

(2012) A B Pizzo et al.   MOLECULAR PSYCHIATRY

Heterogeneity of AMPA receptor trafficking and molecular interactions revealed by superresolution analysis of live cell imaging

(2012) N. Hoze et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatial distribution of Na+-K+-ATPase in dendritic spines dissected by nanoscale superresolution STED microscopy

(2011) Hans Blom et al.   BMC NEUROSCIENCE

Coordinate-based colocalization analysis of single-molecule localization microscopy data

(2011) Sebastian Malkusch et al.   HISTOCHEMISTRY AND CELL BIOLOGY

The roles of flotillin microdomains - endocytosis and beyond

(2011) G. P. Otto et al.   JOURNAL OF CELL SCIENCE

Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT

(2011) M Laura Cremona et al.   NATURE NEUROSCIENCE

SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation

(2011) A. S. Kristensen et al.   PHARMACOLOGICAL REVIEWS

Membrane Cholesterol Modulates the Outward Facing Conformation of the Dopamine Transporter and Alters Cocaine Binding

(2010) Weimin C. Hong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of dopamine transporter function by protein-protein interactions: new discoveries and methodological challenges

(2010) Jacob Eriksen et al.   JOURNAL OF NEUROCHEMISTRY

Superresolution Imaging of Chemical Synapses in the Brain

(2010) Adish Dani et al.   NEURON

Super-Resolution Fluorescence Microscopy

(2009) Bo Huang et al.   Annual Review of Biochemistry

A Biochemical and Functional Protein Complex Involving Dopamine Synthesis and Transport into Synaptic Vesicles

(2009) Etienne A. Cartier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physical and Functional Interaction between the Dopamine Transporter and the Synaptic Vesicle Protein Synaptogyrin-3

(2009) L. A. Egana et al.   JOURNAL OF NEUROSCIENCE

Visualization of Dopamine Transporter Trafficking in Live Neurons by Use of Fluorescent Cocaine Analogs

(2009) J. Eriksen et al.   JOURNAL OF NEUROSCIENCE

Super-resolution microscopy by nanoscale localization of photo-switchable fluorescent probes

(2008) Mark Bates et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Phorbol ester induced trafficking-independent regulation and enhanced phosphorylation of the dopamine transporter associated with membrane rafts and cholesterol

(2008) James D. Foster et al.   JOURNAL OF NEUROCHEMISTRY