Epigenetic alterations in blood mirror age-associated DNA methylation and gene expression changes in human liver

Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding

(2016) Linn Gillberg et al.   DIABETOLOGIA

Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes

(2016) Karl Bacos et al.   Nature Communications

Loss of Nfkb1 leads to early onset aging

(2016) Giovanna M. Bernal et al.   Aging-US

Association Analysis of 29,956 Individuals Confirms That a Low-Frequency Variant atCCND2Halves the Risk of Type 2 Diabetes by Enhancing Insulin Secretion

(2015) Hanieh Yaghootkar et al.   DIABETES

Epigenetic Alterations in Human Liver From Subjects With Type 2 Diabetes in Parallel With Reduced Folate Levels

(2015) Emma Nilsson et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

DNA methylation as a diagnostic and therapeutic target in the battle against Type 2 diabetes

(2015) Tina Rönn et al.   Epigenomics

Genome-wide age-related changes in DNA methylation and gene expression in human PBMCs

(2014) Wilma T. Steegenga et al.   AGE

Lipoprotein subclass metabolism in nonalcoholic steatohepatitis

(2014) Ville T. Männistö et al.   JOURNAL OF LIPID RESEARCH

Obesity accelerates epigenetic aging of human liver

(2014) S. Horvath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA methylation signatures link prenatal famine exposure to growth and metabolism

(2014) Elmar W. Tobi et al.   Nature Communications

Genome-Wide Associations between Genetic and Epigenetic Variation Influence mRNA Expression and Insulin Secretion in Human Pancreatic Islets

(2014) Anders H. Olsson et al.   PLoS Genetics

Genome-Wide DNA Methylation Analysis of Human Pancreatic Islets from Type 2 Diabetic and Non-Diabetic Donors Identifies Candidate Genes That Influence Insulin Secretion

(2014) Tasnim Dayeh et al.   PLoS Genetics

Liver diseases and aging: friends or foes?

(2013) Fareeba Sheedfar et al.   AGING CELL

Fatty Acid–Regulated Transcription Factors in the Liver

(2013) Donald B. Jump et al.   Annual Review of Nutrition

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets

(2013) T. A. Dayeh et al.   DIABETOLOGIA

Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray

(2013) Yi-an Chen et al.   Epigenetics

Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites

(2013) I. Florath et al.   HUMAN MOLECULAR GENETICS

Pleiotropy in complex traits: challenges and strategies

(2013) Nadia Solovieff et al.   NATURE REVIEWS GENETICS

Continuous Aging of the Human DNA Methylome Throughout the Human Lifespan

(2013) Åsa Johansson et al.   PLoS One

A Six Months Exercise Intervention Influences the Genome-wide DNA Methylation Pattern in Human Adipose Tissue

(2013) Tina Rönn et al.   PLoS Genetics

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

Gene expression changes with age in skin, adipose tissue, blood and brain

(2013) Daniel Glass et al.   GENOME BIOLOGY

Methylation ofELOVL2gene as a new epigenetic marker of age

(2012) Paolo Garagnani et al.   AGING CELL

A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data

(2012) Andrew E. Teschendorff et al.   BIOINFORMATICS

Impact of an Exercise Intervention on DNA Methylation in Skeletal Muscle From First-Degree Relatives of Patients With Type 2 Diabetes

(2012) M. D. Nitert et al.   DIABETES

Genome-wide DNA methylation profiles in hepatocellular carcinoma

(2012) Jing Shen et al.   HEPATOLOGY

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Differential DNA Methylation in Purified Human Blood Cells: Implications for Cell Lineage and Studies on Disease Susceptibility

(2012) Lovisa E. Reinius et al.   PLoS One

High density DNA methylation array with single CpG site resolution

(2011) Marina Bibikova et al.   GENOMICS

Activator protein-2α functions as a master regulator of multiple transcription factors in the mouse liver

(2011) Qingjie Li et al.   HEPATOLOGY RESEARCH

Serum interleukin 1 receptor antagonist as an independent marker of non-alcoholic steatohepatitis in humans

(2011) Jussi Pihlajamäki et al.   JOURNAL OF HEPATOLOGY

Evaluation of the Infinium Methylation 450K technology

(2011) Sarah Dedeurwaerder et al.   Epigenomics

Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

(2010) Pan Du et al.   BMC BIOINFORMATICS

Fathers' nutritional legacy

(2010) Michael K. Skinner   NATURE

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

(2010) Benjamin F Voight et al.   NATURE GENETICS

Hepatocellular Carcinoma Displays Distinct DNA Methylation Signatures with Potential as Clinical Predictors

(2010) Hector Hernandez-Vargas et al.   PLoS One

Epigenetics: A Molecular Link Between Environmental Factors and Type 2 Diabetes

(2009) Charlotte Ling et al.   DIABETES

A census of human transcription factors: function, expression and evolution

(2009) Juan M. Vaquerizas et al.   NATURE REVIEWS GENETICS

Chronic liver disease in an ageing population

(2008) J. Frith et al.   AGE AND AGEING

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS

CpG methylation in exon 1 of transcription factor 4 increases with age in normal gastric mucosa and is associated with gene silencing in intestinal-type gastric cancers

(2008) Seung-Kyoon Kim et al.   CARCINOGENESIS