Activity of temocillin, mecillinam, ceftazidime, and ceftazidime/avibactam against carbapenem-non-susceptible Enterobacteriaceae without carbapenemase production

Efficacy of a Ceftazidime-Avibactam Combination in a Murine Model of Septicemia Caused by Enterobacteriaceae Species Producing AmpC or Extended-Spectrum β-Lactamases

(2014) Premavathy Levasseur et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Ceftazidime-avibactam and comparator agents tested against urinary tract isolates from a global surveillance program (2011)

(2014) Robert K. Flamm et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

In vitro activity of mecillinam against Enterobacteriaceae with NDM-1 carbapenemase

(2014) E. C. L. Marrs et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

β-Lactam/β-lactamase inhibitors versus carbapenems for the treatment of sepsis: systematic review and meta-analysis of randomized controlled trials

(2014) Shachaf Shiber et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Activity of avibactam against Enterobacter cloacae producing an extended-spectrum class C  -lactamase enzyme

(2014) S. D. Lahiri et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Avibactam activity against extended-spectrum AmpC  -lactamases

(2014) N. Porres-Osante et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Ceftazidime/avibactam activity tested against Gram-negative bacteria isolated from bloodstream, pneumonia, intra-abdominal and urinary tract infections in US medical centres (2012)

(2014) R. K. Flamm et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

High Rate of Per Oral Mecillinam Treatment Failure in Community-Acquired Urinary Tract Infections Caused by ESBL-Producing Escherichia coli

(2014) Arne Søraas et al.   PLoS One

Antibiotic Trapping by Plasmid-Encoded CMY-2 β-Lactamase Combined with Reduced Outer Membrane Permeability as a Mechanism of Carbapenem Resistance in Escherichia coli

(2013) Wil H. F. Goessens et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A disc diffusion assay for detection of class A, B and OXA-48 carbapenemases in Enterobacteriaceae using phenyl boronic acid, dipicolinic acid and temocillin

(2013) K. van Dijk et al.   CLINICAL MICROBIOLOGY AND INFECTION

Temocillin disc diffusion susceptibility testing by EUCAST methodology

(2013) G. L. Vanstone et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Emerging clinical role of pivmecillinam in the treatment of urinary tract infection in the context of multidrug-resistant bacteria

(2013) S. Dewar et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Description of the metallo-β-lactamase GIM-1 in Acinetobacter pittii

(2013) Martin Kaase et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Clinical and bacteriological effects of pivmecillinam for ESBL-producing Escherichia coli or Klebsiella pneumoniae in urinary tract infections

(2013) F. Jansaker et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Temocillin and piperacillin/tazobactam resistance by disc diffusion as antimicrobial surrogate markers for the detection of carbapenemase-producing Enterobacteriaceae in geographical areas with a high prevalence of OXA-48 producers

(2013) T.-D. Huang et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In vitro activity of temocillin against multidrug-resistant clinical isolates of Escherichia coli, Klebsiella spp. and Enterobacter spp., and evaluation of high-level temocillin resistance as a diagnostic marker for OXA-48 carbapenemase

(2013) N. Woodford et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Comparative study of the efficacy and safety of ceftazidime/avibactam plus metronidazole versus meropenem in the treatment of complicated intra-abdominal infections in hospitalized adults: results of a randomized, double-blind, Phase II trial

(2013) Christopher Lucasti et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Blue-Carba, an Easy Biochemical Test for Detection of Diverse Carbapenemase Producers Directly from Bacterial Cultures

(2013) J. Pires et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Efficacy and safety of ceftazidime–avibactam versus imipenem–cilastatin in the treatment of complicated urinary tract infections, including acute pyelonephritis, in hospitalized adults: results of a prospective, investigator-blinded, randomized study

(2012) José A. Vazquez et al.   CURRENT MEDICAL RESEARCH AND OPINION

Mecillinam/clavulanate combination: a possible option for the treatment of community-acquired uncomplicated urinary tract infections caused by extended-spectrum  -lactamase-producing Escherichia coli

(2012) N. Lampri et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Characterization of  -lactamase and porin mutants of Enterobacteriaceae selected with ceftaroline + avibactam (NXL104)

(2012) D. M. Livermore et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Avibactam is a covalent, reversible, non- -lactam  -lactamase inhibitor

(2012) D. E. Ehmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emergence of Ertapenem Resistance in an Escherichia coli Clinical Isolate Producing Extended-Spectrum β-Lactamase AmpC

(2011) Hélène Guillon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Activity of NXL104 in Combination with β-Lactams against Genetically Characterized Escherichia coli and Klebsiella pneumoniae Isolates Producing Class A Extended-Spectrum β-Lactamases and Class C β-Lactamases

(2011) P. R. S. Lagacé-Wiens et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

International Clinical Practice Guidelines for the Treatment of Acute Uncomplicated Cystitis and Pyelonephritis in Women: A 2010 Update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases

(2011) Kalpana Gupta et al.   CLINICAL INFECTIOUS DISEASES

Membrane permeability, a pivotal function involved in antibiotic resistance and virulence in Enterobacter aerogenes clinical isolates

(2011) J.-P. Lavigne et al.   CLINICAL MICROBIOLOGY AND INFECTION

Diazabicyclooctanes (DBOs): a potent new class of non-β-lactam β-lactamase inhibitors

(2011) Ken Coleman   CURRENT OPINION IN MICROBIOLOGY

In vitro activity of beta-lactam antibiotics against CTX-M-producing Escherichia coli

(2011) M. Tärnberg et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

What remains against carbapenem-resistant Enterobacteriaceae? Evaluation of chloramphenicol, ciprofloxacin, colistin, fosfomycin, minocycline, nitrofurantoin, temocillin and tigecycline

(2011) David M. Livermore et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Antimicrobial susceptibility of Escherichia coli from community-acquired urinary tract infections in Europe: the ECO·SENS study revisited

(2011) Gunnar Kahlmeter et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Temocillin use in England: clinical and microbiological efficacies in infections caused by extended-spectrum and/or derepressed AmpC β-lactamase-producing Enterobacteriaceae

(2011) Indran Balakrishnan et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Efficacy of Pivmecillinam for Treatment of Lower Urinary Tract Infection Caused by Extended-Spectrum β-Lactamase–Producing Escherichia coli and Klebsiella pneumoniae

(2011) Emilia Titelman et al.   Microbial Drug Resistance

Activities of NXL104 Combinations with Ceftazidime and Aztreonam against Carbapenemase-ProducingEnterobacteriaceae

(2010) David M. Livermore et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Oral Treatment Options for Ambulatory Patients with Urinary Tract Infections Caused by Extended-Spectrum- -Lactamase-Producing Escherichia coli

(2010) S. Auer et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A sensitive and specific phenotypic assay for detection of metallo-β-lactamases and KPC in Klebsiella pneumoniae with the use of meropenem disks supplemented with aminophenylboronic acid, dipicolinic acid and cloxacillin

(2010) C.G. Giske et al.   CLINICAL MICROBIOLOGY AND INFECTION

Activity of Temocillin against KPC-Producing Klebsiella pneumoniae and Escherichia coli

(2009) J. M. Adams-Haduch et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Clinical efficacy of temocillin

(2009) N. D. Gupta et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Activity of mecillinam against Escherichia coli resistant to third-generation cephalosporins

(2009) M. Wootton et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In vitro activity of the  -lactamase inhibitor NXL104 against KPC-2 carbapenemase and Enterobacteriaceae expressing KPC carbapenemases

(2009) T. Stachyra et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Sensitive Screening Tests for Suspected Class A Carbapenemase Production in Species of Enterobacteriaceae

(2009) F. Pasteran et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Case Report: Subacute Synovitis of the Knee After a Rose Thorn Injury: Unusual Clinical Picture

(2008) Joris F. H. Duerinckx   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Temocillin revived

(2008) D. M. Livermore et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Spinal infection caused by ESBL-producing Klebsiella pneumoniae treated with Temocillin

(2008) Edward Barton et al.   JOURNAL OF INFECTION