Eslicarbazepine Acetate: A New Improvement on a Classic Drug Family for the Treatment of Partial-Onset Seizures

Pharmacokinetic variability, efficacy and tolerability of eslicarbazepine acetate–A national approach to the evaluation of therapeutic drug monitoring data and clinical outcome

(2017) Torleiv Svendsen et al.   EPILEPSY RESEARCH

EARLY-ESLI study: Long-term experience with eslicarbazepine acetate after first monotherapy failure

(2016) V. Villanueva et al.   ACTA NEUROLOGICA SCANDINAVICA

Real-world data on eslicarbazepine acetate as add-on to antiepileptic monotherapy

(2016) M. Holtkamp et al.   ACTA NEUROLOGICA SCANDINAVICA

Epidemiology, pathophysiology and putative genetic basis of carbamazepine- and oxcarbazepine-induced hyponatremia

(2016) B. Berghuis et al.   EUROPEAN JOURNAL OF NEUROLOGY

Eslicarbazepine acetate for the treatment of partial epilepsy

(2016) Johan Zelano et al.   EXPERT OPINION ON PHARMACOTHERAPY

The Epidemiology of Global Epilepsy

(2016) Anuradha Singh et al.   NEUROLOGIC CLINICS

Conversion to eslicarbazepine acetate monotherapy

(2016) Michael R. Sperling et al.   NEUROLOGY

Efficacy and safety of conversion to monotherapy with eslicarbazepine acetate in adults with uncontrolled partial-onset seizures: a historical-control phase III study

(2015) Mercedes P Jacobson et al.   BMC Neurology

Efficacy and safety of conversion to monotherapy with eslicarbazepine acetate in adults with uncontrolled partial-onset seizures: A randomized historical-control phase III study based in North America

(2015) Michael R. Sperling et al.   EPILEPSIA

Severity and burden of partial-onset seizures in a phase III trial of eslicarbazepine acetate

(2015) Joyce A. Cramer et al.   EPILEPSY & BEHAVIOR

Practical guidance and considerations for transitioning patients from oxcarbazepine or carbamazepine to eslicarbazepine acetate — Expert opinion

(2015) Jukka Peltola et al.   EPILEPSY & BEHAVIOR

Assessing long-term effects of eslicarbazepine acetate on lipid metabolism profile, sodium values and liver function tests

(2015) M. Ley et al.   EPILEPSY RESEARCH

Pharmacokinetic/pharmacodynamic evaluation of eslicarbazepine for the treatment of epilepsy

(2015) Monika Banach et al.   Expert Opinion on Drug Metabolism & Toxicology

Eslicarbazepine and the enhancement of slow inactivation of voltage-gated sodium channels: A comparison with carbamazepine, oxcarbazepine and lacosamide

(2015) Simon Hebeisen et al.   NEUROPHARMACOLOGY

Hyponatremia following esclicarbazepine therapy

(2015) Durgesh K. Gupta et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Clinical utility of eslicarbazepine: current evidence

(2015) Gaetano Zaccara et al.   Drug Design Development and Therapy

A review of the efficacy and safety of eslicarbazepine acetate in the management of partial-onset seizures

(2015) Rodrigo Rocamora   Therapeutic Advances in Neurological Disorders

Eslicarbazepine acetate as adjunctive therapy in patients with uncontrolled partial-onset seizures: Results of a phase III, double-blind, randomized, placebo-controlled trial

(2014) Michael R. Sperling et al.   EPILEPSIA

ILAE Official Report: A practical clinical definition of epilepsy

(2014) Robert S. Fisher et al.   EPILEPSIA

Long-term safety and efficacy of eslicarbazepine acetate in patients with focal seizures: Results of the 1-year ESLIBASE retrospective study

(2014) V. Villanueva et al.   EPILEPSY RESEARCH

Two-year follow-up with eslicarbazepine acetate: a consecutive, retrospective, observational study

(2014) Fernando D. Correia et al.   EPILEPSY RESEARCH

Pharmacokinetics and tolerability of eslicarbazepine acetate and oxcarbazepine at steady state in healthy volunteers

(2013) Christian Elger et al.   EPILEPSIA

Effect of eslicarbazepine acetate on the pharmacokinetics of a combined ethinylestradiol/levonorgestrel oral contraceptive in healthy women

(2013) Amilcar Falcão et al.   EPILEPSY RESEARCH

Effect of repeated administration of eslicarbazepine acetate on the pharmacokinetics of simvastatin in healthy subjects

(2013) Amílcar Falcão et al.   EPILEPSY RESEARCH

Estudio postautorización de la eslicarbazepina en el tratamiento de epilepsias farmacorresistentes: resultados preliminares

(2013) A. Massot et al.   NEUROLOGIA

Frequency of and risk factors for oxcarbazepine-induced severe and symptomatic hyponatremia

(2013) Young-Soo Kim et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Steady-state plasma and cerebrospinal fluid pharmacokinetics and tolerability of eslicarbazepine acetate and oxcarbazepine in healthy volunteers

(2012) Teresa Nunes et al.   EPILEPSIA

Efficacy and safety of eslicarbazepine acetate as add-on treatment in patients with focal-onset seizures: Integrated analysis of pooled data from double-blind phase III clinical studies

(2012) António Gil-Nagel et al.   EPILEPSIA

Pharmacokinetics and drug interactions of eslicarbazepine acetate

(2012) Meir Bialer et al.   EPILEPSIA

Long-term safety and efficacy of eslicarbazepine acetate as adjunctive therapy in the treatment of partial-onset seizures in adults with epilepsy: Results of a 1-year open-label extension study

(2012) Andreas Hufnagel et al.   EPILEPSY RESEARCH

Pharmacokinetics, Drug Interactions and Exposure-Response Relationship of Eslicarbazepine Acetate in Adult Patients with Partial-Onset Seizures

(2011) Amilcar Falcão et al.   CNS DRUGS

Pharmacokinetics of eslicarbazepine acetate at steady-state in adults with partial-onset seizures

(2011) E. Perucca et al.   EPILEPSY RESEARCH

Effect of renal impairment on the pharmacokinetics of eslicarbazepine acetate

(2011) J. Maia et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Effect of eslicarbazepine acetate on the pharmacokinetics of metformin in healthy subjects

(2011) J.-F. Rocha et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Effect of eslicarbazepine acetate on the steady-state pharmacokinetics and pharmacodynamics of warfarin in healthy subjects during a three-stage, open-label, multiple-dose, single-period study

(2010) Manuel Vaz-da-Silva et al.   CLINICAL THERAPEUTICS

Long-term efficacy and safety of eslicarbazepine acetate: Results of a 1-year open-label extension study in partial-onset seizures in adults with epilepsy

(2010) Peter Halász et al.   EPILEPSIA

Eslicarbazepine acetate as adjunctive therapy in adult patients with partial epilepsy

(2010) E. Ben-Menachem et al.   EPILEPSY RESEARCH

Efficacy and safety of 800 and 1200 mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures

(2009) A. Gil-Nagel et al.   ACTA NEUROLOGICA SCANDINAVICA

Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures: A randomized, double-blind, placebo-controlled, parallel-group phase III study

(2009) Christian Elger et al.   EPILEPSIA

Effect of eslicarbazepine acetate on the pharmacokinetics of digoxin in healthy subjects

(2009) Manuel Vaz da Silva et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Pharmacokinetics, Efficacy, and Tolerability of Eslicarbazepine Acetate in Children and Adolescents With Epilepsy

(2008) Luis Almeida et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Transcriptional Upregulation of Cav3.2 Mediates Epileptogenesis in the Pilocarpine Model of Epilepsy

(2008) A. J. Becker et al.   JOURNAL OF NEUROSCIENCE