Arrhythmogenic Cardiomyopathy: the Guilty Party in Adipogenesis

Arrhythmogenic Right Ventricular Cardiomyopathy

(2017) Domenico Corrado et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cardiac Fibro-Adipocyte Progenitors Express Desmosome Proteins and Preferentially Differentiate to Adipocytes Upon Deletion of the Desmoplakin GeneNovelty and Significance

(2016) Raffaella Lombardi et al.   CIRCULATION RESEARCH

Loss of plakoglobin immunoreactivity in intercalated discs in arrhythmogenic right ventricular cardiomyopathy: protein mislocalization versus epitope masking

(2015) Sebastian Kant et al.   CARDIOVASCULAR RESEARCH

Inhibition of Notch Signaling Promotes the Adipogenic Differentiation of Mesenchymal Stem Cells Through Autophagy Activation and PTEN-PI3K/AKT/mTOR Pathway

(2015) Bao-quan Song et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The Hippo Pathway in Heart Development, Regeneration, and Diseases

(2015) Q. Zhou et al.   CIRCULATION RESEARCH

Arrhythmogenic right ventricular cardiomyopathy, clinical manifestations, and diagnosis

(2015) Kristina H. Haugaa et al.   EUROPACE

Cardiac mesenchymal stromal cells are a source of adipocytes in arrhythmogenic cardiomyopathy

(2015) E. Sommariva et al.   EUROPEAN HEART JOURNAL

Pathways commonly dysregulated in mouse and human obese adipose tissue: FAT/CD36 modulates differentiation and lipogenesis

(2015) E Berger et al.   Adipocyte

microRNA-320/RUNX2 axis regulates adipocytic differentiation of human mesenchymal (skeletal) stem cells

(2014) D Hamam et al.   Cell Death & Disease

Deconstructing the roles of glucocorticoids in adipose tissue biology and the development of central obesity

(2013) Mi-Jeong Lee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Hippo Pathway Is Activated and Is a Causal Mechanism for Adipogenesis in Arrhythmogenic Cardiomyopathy

(2013) Suet Nee Chen et al.   CIRCULATION RESEARCH

Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs

(2013) Changsung Kim et al.   NATURE

Perilipin1 promotes unilocular lipid droplet formation through the activation of Fsp27 in adipocytes

(2013) Zhiqi Sun et al.   Nature Communications

Plakophilin-2 and the migration, differentiation and transformation of cells derived from the epicardium of neonatal rat hearts

(2011) Stephanie A. Matthes et al.   CELL COMMUNICATION AND ADHESION

Mitochondrial Complex III ROS Regulate Adipocyte Differentiation

(2011) Kathryn V. Tormos et al.   Cell Metabolism

Epicardial-Derived Cell Epithelial-to-Mesenchymal Transition and Fate Specification Require PDGF Receptor Signaling

(2011) Christopher L. Smith et al.   CIRCULATION RESEARCH

Nuclear Plakoglobin Is Essential for Differentiation of Cardiac Progenitor Cells to Adipocytes in Arrhythmogenic Right Ventricular Cardiomyopathy

(2011) Raffaella Lombardi et al.   CIRCULATION RESEARCH

Arrhythmogenic Cardiomyopathy

(2011) Kalliopi Pilichou et al.   Circulation-Cardiovascular Genetics

Pathophysiology of arrhythmogenic cardiomyopathy

(2011) Cristina Basso et al.   Nature Reviews Cardiology

Forming functional fat: a growing understanding of adipocyte differentiation

(2011) Ana G. Cristancho et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A potential link between peroxisome proliferator-activated receptor signalling and the pathogenesis of arrhythmogenic right ventricular cardiomyopathy

(2009) F. Djouadi et al.   CARDIOVASCULAR RESEARCH

Genetic Fate Mapping Identifies Second Heart Field Progenitor Cells As a Source of Adipocytes in Arrhythmogenic Right Ventricular Cardiomyopathy

(2009) Raffaella Lombardi et al.   CIRCULATION RESEARCH

Adipocyte Fatty Acid–Binding Protein Suppresses Cardiomyocyte Contraction

(2009) Valéria Lamounier-Zepter et al.   CIRCULATION RESEARCH

Interferon γ Attenuates Insulin Signaling, Lipid Storage, and Differentiation in Human Adipocytes via Activation of the JAK/STAT Pathway

(2009) Fiona C. McGillicuddy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BMP signaling pathway is required for commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage

(2009) H. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nkx2-5- and Isl1-expressing cardiac progenitors contribute to proepicardium

(2008) Bin Zhou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Markedly increased intracellular lipid droplets and disruption of intercellular junctions in biopsied myocardium from a patient with arrhythmogenic right ventricular cardiomyopathy

(2008) Shuichi Fujita et al.   HEART AND VESSELS

Hedgehog Signaling Alters Adipocyte Maturation of Human Mesenchymal Stem Cells

(2008) Coralie Fontaine et al.   STEM CELLS

Adipogenesis and WNT signalling

(2008) Constantinos Christodoulides et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM