The cryo-thermal therapy eradicated melanoma in mice by eliciting CD4+ T-cell-mediated antitumor memory immune response

Targeting the tumor microenvironment: removing obstruction to anticancer immune responses and immunotherapy

(2016) J. M. Pitt et al.   ANNALS OF ONCOLOGY

Mycobacterium tuberculosis PE27 activates dendritic cells and contributes to Th1-polarized memory immune responses during in vivo infection

(2016) Woo Sik Kim et al.   IMMUNOBIOLOGY

The future of biology in driving the field of hyperthermia

(2016) Mark W. Dewhirst et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Final Results of the Sunbelt Melanoma Trial: A Multi-Institutional Prospective Randomized Phase III Study Evaluating the Role of Adjuvant High-Dose Interferon Alfa-2b and Completion Lymph Node Dissection for Patients Staged by Sentinel Lymph Node Biopsy

(2016) Kelly M. McMasters et al.   JOURNAL OF CLINICAL ONCOLOGY

Development of immuno-oncology drugs — from CTLA4 to PD1 to the next generations

(2016) Axel Hoos   NATURE REVIEWS DRUG DISCOVERY

Interleukin-6 Induced “Acute” Phenotypic Microenvironment Promotes Th1 Anti-Tumor Immunity in Cryo-Thermal Therapy Revealed By Shotgun and Parallel Reaction Monitoring Proteomics

(2016) Ting Xue et al.   Theranostics

Cryo-thermal therapy elicits potent anti-tumor immunity by inducing extracellular Hsp70-dependent MDSC differentiation

(2016) Jun Zhu et al.   Scientific Reports

MicroRNAs are implicated in the suppression of CD4+CD25− conventional T cell proliferation by CD4+CD25+ regulatory T cells

(2015) Sha Zhou et al.   MOLECULAR IMMUNOLOGY

Adoptive cell transfer as personalized immunotherapy for human cancer

(2015) S. A. Rosenberg et al.   SCIENCE

T-cell exhaustion in the tumor microenvironment

(2015) Y Jiang et al.   Cell Death & Disease

Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma

(2015) Lien Vandenberk et al.   OncoImmunology

Recent Advances in Thermal Treatment Techniques and Thermally Induced Immune Responses Against Cancer

(2014) J. F. Bai et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Two phase I dose-escalation/pharmacokinetics studies of low temperature liposomal doxorubicin (LTLD) and mild local hyperthermia in heavily pretreated patients with local regionally recurrent breast cancer

(2014) Timothy M. Zagar et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Local tumour hyperthermia as immunotherapy for metastatic cancer

(2014) Seiko Toraya-Brown et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Anti-CD20 therapy induces a memory Th1 response through the IFN-γ/IL-12 axis and prevents protumor regulatory T-cell expansion in mice

(2014) C Deligne et al.   LEUKEMIA

CD4 T-cell Subsets and Tumor Immunity: The Helpful and the Not-so-Helpful

(2014) H.-J. Kim et al.   Cancer Immunology Research

Immune-suppressive properties of the tumor microenvironment

(2013) Jürgen C. Becker et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Interferon response factor 3 is crucial to poly-I:C induced NK cell activity and control of B16 melanoma growth

(2013) Tyler C. Moore et al.   CANCER LETTERS

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Numerical Simulation of a New Probe for the Alternate Cooling and Heating of a Subcutaneous Mouse Tumor Model

(2013) Zhanghao Cai et al.   NUMERICAL HEAT TRANSFER PART A-APPLICATIONS

Temperature Matters! And Why It Should Matter to Tumor Immunologists

(2013) E. A. Repasky et al.   Cancer Immunology Research

T-Regulatory Cells: Key Players in Tumor Immune Escape and Angiogenesis

(2012) A. Facciabene et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Systematic Review of Medical Treatment in Melanoma: Current Status and Future Prospects

(2011) C. Garbe et al.   ONCOLOGIST

Naive tumor-specific CD4+T cells differentiated in vivo eradicate established melanoma

(2010) Ying Xie et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tumor-reactive CD4+T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts

(2010) Sergio A. Quezada et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Intratumoural GM-CSF microspheres and CTLA-4 blockade enhance the antitumour immunity induced by thermal ablation in a subcutaneous murine hepatoma model

(2009) Zubing Chen et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Hyperthermia on immune regulation: A temperature’s story

(2008) Hua-Gang Zhang et al.   CANCER LETTERS

Cryo-immunology: A review of the literature and proposed mechanisms for stimulatory versus suppressive immune responses

(2008) Michael S. Sabel   CRYOBIOLOGY