A new molecular mechanism underlying the EGCG-mediated autophagic modulation of AFP in HepG2 cells

Annual Report to the Nation on the Status of Cancer, 1975-2012, featuring the increasing incidence of liver cancer

(2016) A. Blythe Ryerson et al.   CANCER

Alpha-fetoprotein is a biomarker of unfolded protein response and altered proteostasis in hepatocellular carcinoma cells exposed to sorafenib

(2016) Aline Houessinon et al.   CANCER LETTERS

Alpha fetoprotein plays a critical role in promoting metastasis of hepatocellular carcinoma cells

(2016) Yan Lu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Reduction in Autophagy by (-)-Epigallocatechin-3-Gallate (EGCG): a Potential Mechanism of Prevention of Mitochondrial Dysfunction After Subarachnoid Hemorrhage

(2016) Ying Chen et al.   MOLECULAR NEUROBIOLOGY

A novel anti-alpha-fetoprotein single-chain variable fragment displays anti-tumor effects in HepG2 cells as a single agent or in combination with paclitaxel

(2016) Xiaonan Ji et al.   TUMOR BIOLOGY

MCOLN1 is a ROS sensor in lysosomes that regulates autophagy

(2016) Xiaoli Zhang et al.   Nature Communications

Epigallocatechin-3-gallate attenuates apoptosis and autophagy in concanavalin A-induced hepatitis by inhibiting BNIP3

(2016) Sainan Li et al.   Drug Design Development and Therapy

Epigallocatechin Gallate Nanodelivery Systems for Cancer Therapy

(2016) Andreia Granja et al.   Nutrients

EGCG in Green Tea Induces Aggregation of HMGB1 Protein through Large Conformational Changes with Polarized Charge Redistribution

(2016) Xuan-Yu Meng et al.   Scientific Reports

Effects of AFP gene silencing on Survivin mRNA expression inhibition in HepG2 cells

(2015) Z.L. Fang et al.   GENETICS AND MOLECULAR RESEARCH

Circulating microRNAs as biomarkers for diagnosis of early hepatocellular carcinoma associated with hepatitis B virus

(2015) Chao-Hung Hung et al.   INTERNATIONAL JOURNAL OF CANCER

EGCG synergizes the therapeutic effect of cisplatin and oxaliplatin through autophagic pathway in human colorectal cancer cells

(2015) Fen Hu et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

FGF signalling regulates bone growth through autophagy

(2015) Laura Cinque et al.   NATURE

Green tea component epigallocatechin-3-gallate decreases expression of osteopontin via a decrease in mRNA half-life in cell lines of metastatic hepatocellular carcinoma

(2015) Matthew A.C. Zapf et al.   SURGERY

Targeting increased copper levels in diethylnitrosamine induced hepatocellular carcinoma cells in rats by epigallocatechin-3-gallate

(2015) Mohd Farhan et al.   TUMOR BIOLOGY

EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism

(2015) Alice Modernelli et al.   Scientific Reports

The green tea polyphenol (−)-epigallocatechin gallate prevents the aggregation of tau protein into toxic oligomers at substoichiometric ratios

(2014) Heike J. Wobst et al.   FEBS LETTERS

Epigallocatechin-3-gallate induces the apoptosis of hepatocellular carcinoma LM6 cells but not non-cancerous liver cells

(2014) YUNJUAN ZHANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Chemopreventive and hepatoprotective effects of Epigallocatechin-gallate against hepatocellular carcinoma: role of heparan sulfate proteoglycans pathway

(2014) Mohamed M. Darweish et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Self-assembled micellar nanocomplexes comprising green tea catechin derivatives and protein drugs for cancer therapy

(2014) Joo Eun Chung et al.   Nature Nanotechnology

Autophagy Inhibition Contributes to the Synergistic Interaction between EGCG and Doxorubicin to Kill the Hepatoma Hep3B Cells

(2014) Li Chen et al.   PLoS One

Synthesis of Autophagosomal Marker Protein LC3-II under Detergent-Free Conditions

(2013) Yi-Chao Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Inhibitory impacts of chemically modified tetracycline-3 and underlying mechanism in human cervical cancer cells

(2013) Lin Zhao et al.   ANTI-CANCER DRUGS

Toward the Molecular Mechanism(s) by Which EGCG Treatment Remodels Mature Amyloid Fibrils

(2013) Fernando L. Palhano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Prostanoid EP1 receptor as the target of (−)-epigallocatechin-3-gallate in suppressing hepatocellular carcinoma cells in vitro

(2012) Juan Jin et al.   ACTA PHARMACOLOGICA SINICA

Alpha-fetoprotein acts as a novel signal molecule and mediates transcription of Fn14 in human hepatocellular carcinoma

(2012) Shanshan Wang et al.   JOURNAL OF HEPATOLOGY

Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy

(2012) Chinatsu Otomo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Promoting Tumorigenesis by Suppressing Autophagy

(2012) I. Koren et al.   SCIENCE

EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages

(2011) Wei Li et al.   BIOCHEMICAL PHARMACOLOGY

Web servers and services for electrostatics calculations with APBS and PDB2PQR

(2011) Samir Unni et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Molecular Insight into Conformational Transition of Amyloid β-Peptide 42 Inhibited by (−)-Epigallocatechin-3-gallate Probed by Molecular Simulations

(2011) Fu-Feng Liu et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Alpha-fetoprotein: A new member of intracellular signal molecules in regulation of the PI3K/AKT signaling in human hepatoma cell lines

(2010) Mengsen Li et al.   INTERNATIONAL JOURNAL OF CANCER

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

(2010) Jan Bieschke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation