HDAC6 inhibition by tubastatin A is protective against oxidative stress in a photoreceptor cell line and restores visual function in a zebrafish model of inherited blindness

A review of the mechanisms of cone degeneration in retinitis pigmentosa

(2016) Daniel S. Narayan et al.   ACTA OPHTHALMOLOGICA

A method for isolation of cone photoreceptors from adult zebrafish retinae

(2016) Antonino Glaviano et al.   BMC NEUROSCIENCE

The Role of the Reactive Oxygen Species and Oxidative Stress in the Pathomechanism of the Age-Related Ocular Diseases and Other Pathologies of the Anterior and Posterior Eye Segments in Adults

(2016) Małgorzata Nita et al.   Oxidative Medicine and Cellular Longevity

Pharmacological modulation of HDAC1 and HDAC6 in vivo in a zebrafish model: Therapeutic implications for Parkinson’s disease

(2016) Brígida R. Pinho et al.   PHARMACOLOGICAL RESEARCH

Roles of peroxiredoxins in cancer, neurodegenerative diseases and inflammatory diseases

(2016) Mi Hee Park et al.   PHARMACOLOGY & THERAPEUTICS

Carnosic acid slows photoreceptor degeneration in the Pde6b rd10 mouse model of retinitis pigmentosa

(2016) Kai Kang et al.   Scientific Reports

Is There Excess Oxidative Stress and Damage in Eyes of Patients with Retinitis Pigmentosa?

(2015) Peter A. Campochiaro et al.   ANTIOXIDANTS & REDOX SIGNALING

Expression and distribution of peroxiredoxins in the retina and optic nerve

(2015) Glyn Chidlow et al.   Brain Structure & Function

A role of Heat Shock Protein 70 in Photoreceptor Cell Death: Potential as a Novel Therapeutic Target in Retinal Degeneration

(2015) Ayako Furukawa et al.   CNS Neuroscience & Therapeutics

New Zebrafish Models of Neurodegeneration

(2015) Rebeca Martín-Jiménez et al.   Current Neurology and Neuroscience Reports

Pharmacological approaches to retinitis pigmentosa: A laboratory perspective

(2015) Viviana Guadagni et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Zebrafish—on the move towards ophthalmological research

(2014) J Chhetri et al.   EYE

α-Tubulin K40 acetylation is required for contact inhibition of proliferation and cell–substrate adhesion

(2014) Andrea Aguilar et al.   MOLECULAR BIOLOGY OF THE CELL

HDAC6–ubiquitin interaction controls the duration of HSF1 activation after heat shock

(2014) Lydia Pernet et al.   MOLECULAR BIOLOGY OF THE CELL

Cellular responses following retinal injuries and therapeutic approaches for neurodegenerative diseases

(2014) Nicolás Cuenca et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Causes and consequences of inherited cone disorders

(2014) Susanne Roosing et al.   PROGRESS IN RETINAL AND EYE RESEARCH

The heat-shock response co-inducer arimoclomol protects against retinal degeneration in rhodopsin retinitis pigmentosa

(2014) D A Parfitt et al.   Cell Death & Disease

Inclusion body formation, macroautophagy, and the role of HDAC6 in neurodegeneration

(2013) Christiane Richter-Landsberg et al.   ACTA NEUROPATHOLOGICA

The cell stress machinery and retinal degeneration

(2013) Dimitra Athanasiou et al.   FEBS LETTERS

Hsp90 inhibition protects against inherited retinal degeneration

(2013) Mònica Aguilà et al.   HUMAN MOLECULAR GENETICS

Peroxiredoxin I and II in Human Eyes

(2013) Sonja Klebe et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Altered Antioxidant-Oxidant Status in the Aqueous Humor and Peripheral Blood of Patients with Retinitis Pigmentosa

(2013) Cristina Martínez-Fernández de la Cámara et al.   PLoS One

Early safety assessment of human oculotoxic drugs using the zebrafish visualmotor response

(2013) Sudhakar Deeti et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

HDAC6 at the Intersection of Neuroprotection and Neurodegeneration

(2012) Constantin d'Ydewalle et al.   TRAFFIC

Post-translational modifications of Hsp90 and their contributions to chaperone regulation

(2011) Mehdi Mollapour et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Peroxiredoxin Functions as a Peroxidase and a Regulator and Sensor of Local Peroxides

(2011) Sue Goo Rhee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease

(2011) Constantin d'Ydewalle et al.   NATURE MEDICINE

Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions

(2011) Carsten Janke et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

KRIBB11 Inhibits HSP70 Synthesis through Inhibition of Heat Shock Factor 1 Function by Impairing the Recruitment of Positive Transcription Elongation Factor b to thehsp70Promoter

(2010) Young Ju Yoon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-acetylcysteine promotes long-term survival of cones in a model of retinitis pigmentosa

(2010) Sun Young Lee et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Rational Design and Simple Chemistry Yield a Superior, Neuroprotective HDAC6 Inhibitor, Tubastatin A

(2010) Kyle V. Butler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

HspB1 (Hsp 27) Expression and Neuroprotection in the Retina

(2010) Amanda M. O’Reilly et al.   MOLECULAR NEUROBIOLOGY

Chemical phylogenetics of histone deacetylases

(2010) James E Bradner et al.   Nature Chemical Biology

Targeting the correct HDAC(s) to treat cognitive disorders

(2010) André Fischer et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse

(2010) J Sancho-Pelluz et al.   Cell Death & Disease

HDAC6 is a target for protection and regeneration following injury in the nervous system

(2009) M. A. Rivieccio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HDAC6 inhibition enhances 17-AAG-mediated abrogation of hsp90 chaperone function in human leukemia cells

(2008) R. Rao et al.   BLOOD

Histone deacetylase 6 interacts with the microtubule-associated protein tau

(2008) Huiping Ding et al.   JOURNAL OF NEUROCHEMISTRY

Therapeutic application of histone deacetylase inhibitors for central nervous system disorders

(2008) Aleksey G. Kazantsev et al.   NATURE REVIEWS DRUG DISCOVERY

HDAC6 is a specific deacetylase of peroxiredoxins and is involved in redox regulation

(2008) R. B. Parmigiani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA