Binding of doxorubicin to Sorcin impairs cell death and increases drug resistance in cancer cells

Sorcin Links Pancreatic β-Cell Lipotoxicity to ER Ca2+Stores

(2016) Alice Marmugi et al.   DIABETES

Structural basis of Sorcin-mediated calcium-dependent signal transduction

(2015) Andrea Ilari et al.   Scientific Reports

Reversing Effect of Sorcin in the Drug Resistance of Human Nasopharyngeal Carcinoma

(2014) Xuebing Liu et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Increased expression of sorcin is associated with multidrug resistance in leukemia cells via up-regulation of MDR1 expression through cAMP response element-binding protein

(2014) Nobuyuki Yamagishi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sorcin, a Calcium Binding Protein Involved in the Multidrug Resistance Mechanisms in Cancer Cells

(2014) Gianni Colotti et al.   MOLECULES

Sorcin Links Calcium Signaling to Vesicle Trafficking, Regulates Polo-Like Kinase 1 and Is Necessary for Mitosis

(2014) Vasiliki S. Lalioti et al.   PLoS One

Drug Resistance in Cancer: An Overview

(2014) Genevieve Housman et al.   Cancers

Sorcin silencing inhibits epithelial-to-mesenchymal transition and suppresses breast cancer metastasis in vivo

(2013) Yunhui Hu et al.   BREAST CANCER RESEARCH AND TREATMENT

Population pharmacokinetics of doxorubicin: establishment of a NONMEM model for adults and children older than 3 years

(2013) Nina E. Kontny et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Inhibition of sorcin reverses multidrug resistance of K562/A02 cells and MCF-7/A02 cells via regulating apoptosis-related proteins

(2013) Yunhui Hu et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

P-glycoprotein ABCB1: a major player in drug handling by mammals

(2013) Piet Borst et al.   JOURNAL OF CLINICAL INVESTIGATION

Resistance to paclitxel in breast carcinoma cells requires a quality control of mitochondrial antiapoptotic proteins by TRAP1

(2013) Francesca Maddalena et al.   Molecular Oncology

Sorcin, a potential therapeutic target for reversing multidrug resistance in cancer

(2012) Bei-Bei Zheng et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Unravelling molecular mechanisms in the fluorescence spectra of doxorubicin in aqueous solution by femtosecond fluorescence spectroscopy

(2012) Pascale Changenet-Barret et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Sorcin Induces a Drug-Resistant Phenotype in Human Colorectal Cancer by Modulating Ca2+ Homeostasis

(2011) F. Maddalena et al.   CANCER RESEARCH

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Mitochondrial Chaperone Trap1 and the Calcium Binding Protein Sorcin Interact and Protect Cells against Apoptosis Induced by Antiblastic Agents

(2010) M. Landriscina et al.   CANCER RESEARCH

Activation of the cardiac Na+–Ca2+ exchanger by sorcin via the interaction of the respective Ca2+-binding domains

(2010) Carlotta Zamparelli et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Moderate Increase in Mdr1a/1b Expression Causes In vivo Resistance to Doxorubicin in a Mouse Model for Hereditary Breast Cancer

(2009) M. Pajic et al.   CANCER RESEARCH

Structural Basis for Ca2+-Dependent Formation of ALG-2/Alix Peptide Complex: Ca2+/EF3-Driven Arginine Switch Mechanism

(2008) Hironori Suzuki et al.   STRUCTURE

Molecular basis for the impaired function of the natural F112L sorcin mutant: X-ray crystal structure, calcium affinity, and interaction with annexin VII and the ryanodine receptor

(2007) Stefano Franceschini et al.   FASEB JOURNAL