TRIM45 functions as a tumor suppressor in the brain via its E3 ligase activity by stabilizing p53 through K63-linked ubiquitination

The TRIM-FLMN protein TRIM45 directly interacts with RACK1 and negatively regulates PKC-mediated signaling pathway

(2014) T Sato et al.   ONCOGENE

RNF26 Temporally Regulates Virus-Triggered Type I Interferon Induction by Two Distinct Mechanisms

(2014) Yue Qin et al.   PLoS Pathogens

Deubiquitylation and stabilization of PTEN by USP13

(2013) Jinsong Zhang et al.   NATURE CELL BIOLOGY

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

Ubiquitin-Binding Proteins: Decoders of Ubiquitin-Mediated Cellular Functions

(2012) Koraljka Husnjak et al.   Annual Review of Biochemistry

TRIM45 negatively regulates NF-κB-mediated transcription and suppresses cell proliferation

(2012) Mio Shibata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2005-2009

(2012) T. A. Dolecek et al.   NEURO-ONCOLOGY

Exciting New Advances in Neuro-Oncology: The Avenue to a Cure for Malignant Glioma

(2010) E. G. Van Meir et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Regulation of the p53 pathway by ubiquitin and related proteins

(2010) Andreas Hock et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

p53 post-translational modification: deregulated in tumorigenesis

(2010) Chao Dai et al.   TRENDS IN MOLECULAR MEDICINE

The Pathobiology of Glioma Tumors

(2009) Candece L. Gladson et al.   Annual Review of Pathology-Mechanisms of Disease

The multiple levels of regulation by p53 ubiquitination

(2009) J T Lee et al.   CELL DEATH AND DIFFERENTIATION

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE