Regulator of G protein signaling 2 is a key regulator of pancreatic β-cell mass and function

Gαi/o-coupled receptor signaling restricts pancreatic β-cell expansion

(2015) Miles Berger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Islet β cell mass in diabetes and how it relates to function, birth, and death

(2013) Gordon C. Weir et al.   Annals of the New York Academy of Sciences

Regulator of G Protein Signaling 2 Deficiency Causes Endothelial Dysfunction and Impaired Endothelium-derived Hyperpolarizing Factor-mediated Relaxation by Dysregulating Gi/oSignaling

(2012) Patrick Osei-Owusu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stimulating beta cell replication and improving islet graft function by GPR119 agonists

(2011) Jie Gao et al.   TRANSPLANT INTERNATIONAL

The Gq/G11-mediated signaling pathway is critical for autocrine potentiation of insulin secretion in mice

(2010) Antonia Sassmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Translational control by RGS2

(2009) Chau H. Nguyen et al.   JOURNAL OF CELL BIOLOGY

Relationship between β-cell mass and diabetes onset

(2008) A. V. Matveyenko et al.   DIABETES OBESITY & METABOLISM

Targeting β-Cell Mass in Type 2 Diabetes: Promise and Limitations of New Drugs Based on Incretins

(2008) Marzieh Salehi et al.   ENDOCRINE REVIEWS

The Antiinflammatory Cytokine Interleukin-1 Receptor Antagonist Protects from High-Fat Diet-Induced Hyperglycemia

(2008) Nadine S. Sauter et al.   ENDOCRINOLOGY