The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth
Authors
Keywords
-
Journal
Cell Death & Disease
Volume 8, Issue 6, Pages e2843
Publisher
Springer Nature
Online
2017-06-01
DOI
10.1038/cddis.2017.235
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- DNA damage-induced apoptosis suppressor (DDIAS), a novel target of NFATc1, is associated with cisplatin resistance in lung cancer
- (2016) Joo-Young Im et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Identification of Targets of the HIF-1 Inhibitor IDF-11774 Using Alkyne-Conjugated Photoaffinity Probes
- (2016) Hyun Seung Ban et al. BIOCONJUGATE CHEMISTRY
- Hypoxia-inducible factor (HIF) inhibitors: a patent survey (2011-2015)
- (2016) Hyun Seung Ban et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- A Lactate-Induced Response to Hypoxia
- (2015) Dong Chul Lee et al. CELL
- Synthesis and Structure–Activity Relationship Study of Chemical Probes as Hypoxia Induced Factor-1α/Malate Dehydrogenase 2 Inhibitors
- (2014) Ravi Naik et al. JOURNAL OF MEDICINAL CHEMISTRY
- Identification of Malate Dehydrogenase 2 as a Target Protein of the HIF-1 Inhibitor LW6 using Chemical Probes
- (2013) Kyeong Lee et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The HSP70 family and cancer
- (2013) M. E. Murphy CARCINOGENESIS
- HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
- (2013) Gregg L. Semenza JOURNAL OF CLINICAL INVESTIGATION
- Targeting cellular metabolism to improve cancer therapeutics
- (2013) Y Zhao et al. Cell Death & Disease
- The HIF-pathway inhibitor NSC-134754 induces metabolic changes and anti-tumour activity while maintaining vascular function
- (2012) L C J Baker et al. BRITISH JOURNAL OF CANCER
- Arylsulfonamide KCN1 Inhibits In Vivo Glioma Growth and Interferes with HIF Signaling by Disrupting HIF-1 Interaction with Cofactors p300/CBP
- (2012) S. Yin et al. CLINICAL CANCER RESEARCH
- Targeting Cancer Metabolism
- (2012) B. A. Teicher et al. CLINICAL CANCER RESEARCH
- Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors
- (2012) Yan Xia et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Tonicity enhancer binding protein (TonEBP) and hypoxia-inducible factor (HIF) coordinate heat shock protein 70 (Hsp70) expression in hypoxic nucleus pulposus cells: Role of Hsp70 in HIF-1α degradation
- (2012) Shilpa S Gogate et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Synthesis and Structure–Activity Relationship of (E)-Phenoxyacrylic Amide Derivatives as Hypoxia-Inducible Factor (HIF) 1α Inhibitors
- (2012) Ravi Naik et al. JOURNAL OF MEDICINAL CHEMISTRY
- MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer
- (2012) N. V. Chaika et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- LW6, a novel HIF-1 inhibitor, promotes proteasomal degradation of HIF-1α via upregulation of VHL in a colon cancer cell line
- (2010) Kyeong Lee et al. BIOCHEMICAL PHARMACOLOGY
- HIF-1: upstream and downstream of cancer metabolism
- (2009) Gregg L Semenza CURRENT OPINION IN GENETICS & DEVELOPMENT
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Cancer Cell Metabolism: Warburg and Beyond
- (2008) Peggy P. Hsu et al. CELL
- Transcriptional upregulation of HSP70-2 by HIF-1 in cancer cells in response to hypoxia
- (2008) Wen-Jie Huang et al. INTERNATIONAL JOURNAL OF CANCER
- Molecular mechanisms for the activity of PX-478, an antitumor inhibitor of the hypoxia-inducible factor-1
- (2008) M. Y. Koh et al. MOLECULAR CANCER THERAPEUTICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation