The TGF-β Family in Caenorhabditis elegans

Latent TGF-β-binding proteins

(2015) Ian B. Robertson et al.   MATRIX BIOLOGY

Aβ reduction in BACE1 heterozygous null 5XFAD mice is associated with transgenic APP level

(2015) Katherine R Sadleir et al.   Molecular Neurodegeneration

Structural determinants of Smad function in TGF-β signaling

(2015) Maria J. Macias et al.   TRENDS IN BIOCHEMICAL SCIENCES

Promotion of Bone Morphogenetic Protein Signaling by Tetraspanins and Glycosphingolipids

(2015) Zhiyu Liu et al.   PLoS Genetics

CEH-28 activates dbl-1 expression and TGF-β signaling in the C. elegans M4 neuron

(2014) Kalpana Ramakrishnan et al.   DEVELOPMENTAL BIOLOGY

Regulation of Extracellular Matrix Organization by BMP Signaling in Caenorhabditis elegans

(2014) Robbie D. Schultz et al.   PLoS One

Systemic Activin signaling independently regulates sugar homeostasis, cellular metabolism, and pH balance in Drosophila melanogaster

(2014) A. C. Ghosh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BMP signaling requires retromer-dependent recycling of the type I receptor

(2014) R. J. Gleason et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors

(2014) L. Katsimpardi et al.   SCIENCE

Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle

(2014) M. Sinha et al.   SCIENCE

Insights from the worm: The C. elegans model for innate immunity

(2014) Maria A. Ermolaeva et al.   SEMINARS IN IMMUNOLOGY

Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy

(2013) Francesco S. Loffredo et al.   CELL

The neogenin/DCC homolog UNC-40 promotes BMP signaling via the RGM protein DRAG-1 in C. elegans

(2013) Chenxi Tian et al.   DEVELOPMENT

Regulation of lipid droplet size and phospholipid composition by stearoyl-CoA desaturase

(2013) Xun Shi et al.   JOURNAL OF LIPID RESEARCH

Activin Signaling Targeted by Insulin/dFOXO Regulates Aging and Muscle Proteostasis in Drosophila

(2013) Hua Bai et al.   PLoS Genetics

Coated Pit-mediated Endocytosis of the Type I Transforming Growth Factor-β (TGF-β) Receptor Depends on a Di-leucine Family Signal and Is Not Required for Signaling

(2012) Keren E. Shapira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

System Wide Analysis of the Evolution of Innate Immunity in the Nematode Model Species Caenorhabditis elegans and Pristionchus pacificus

(2012) Amit Sinha et al.   PLoS One

C. elegans ADAMTS ADT-2 regulates body size by modulating TGFβ signaling and cuticle collagen organization

(2011) Thilini Fernando et al.   DEVELOPMENTAL BIOLOGY

Emerging Roles for the Transforming Growth Factor-β Superfamily in Regulating Adiposity and Energy Expenditure

(2011) Nader Zamani et al.   ENDOCRINE REVIEWS

Non-stringent tissue-source requirements for BMP ligand expression in regulation of body size in Caenorhabditis elegans

(2011) CATHY SAVAGE-DUNN et al.   Genetics Research

Multiple doublesex-Related Genes Specify Critical Cell Fates in a C. elegans Male Neural Circuit

(2011) Meagan S. Siehr et al.   PLoS One

Regulation of genes affecting body size and innate immunity by the DBL-1/BMP-like pathway in Caenorhabditis elegans

(2010) Andrew F Roberts et al.   BMC DEVELOPMENTAL BIOLOGY

Alternative trans-splicing of Caenorhabditis elegans sma-9/schnurri generates a short transcript that provides tissue-specific function in BMP signaling

(2010) Jianghua Yin et al.   BMC MOLECULAR BIOLOGY

TGF-β and Insulin Signaling Regulate Reproductive Aging via Oocyte and Germline Quality Maintenance

(2010) Shijing Luo et al.   CELL

The RGM protein DRAG-1 positively regulates a BMP-like signaling pathway in Caenorhabditis elegans

(2010) C. Tian et al.   DEVELOPMENT

Antagonistic Smad transcription factors control the dauer/non-dauer switch in C. elegans

(2010) D. Park et al.   DEVELOPMENT

Neogenin, a Receptor for Bone Morphogenetic Proteins

(2010) Meiko Hagihara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The endocytic matrix

(2010) Giorgio Scita et al.   NATURE

The Amphimedon queenslandica genome and the evolution of animal complexity

(2010) Mansi Srivastava et al.   NATURE

Developmental control of lateralized neuron size in the nematode Caenorhabditis elegans

(2010) Andrew D Goldsmith et al.   Neural Development

Caenorhabditis elegans SMA-10/LRIG Is a Conserved Transmembrane Protein that Enhances Bone Morphogenetic Protein Signaling

(2010) Tina L. Gumienny et al.   PLoS Genetics

Emergence, development and diversification of the TGF-β signalling pathway within the animal kingdom

(2009) Lukasz Huminiecki et al.   BMC EVOLUTIONARY BIOLOGY

Gbb/BMP signaling is required to maintain energy homeostasis in Drosophila

(2009) Shannon L. Ballard et al.   DEVELOPMENTAL BIOLOGY

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

(2009) Billy Andriopoulos Jr et al.   NATURE GENETICS

Neuroimmune regulation of antimicrobial peptide expression by a noncanonical TGF-β signaling pathway in Caenorhabditis elegans epidermis

(2009) Olivier Zugasti et al.   NATURE IMMUNOLOGY

UNC-129 regulates the balance between UNC-40 dependent and independent UNC-5 signaling pathways

(2009) Lesley T MacNeil et al.   NATURE NEUROSCIENCE

Pathways and mechanisms of endocytic recycling

(2009) Barth D. Grant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Endocytosis and signalling: intertwining molecular networks

(2009) Alexander Sorkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TGF-ß Sma/Mab Signaling Mutations Uncouple Reproductive Aging from Somatic Aging

(2009) Shijing Luo et al.   PLoS Genetics

Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin

(2008) Y. Xia et al.   BLOOD

Neural and Molecular Dissection of a C. elegans Sensory Circuit that Regulates Fat and Feeding

(2008) Elisabeth R. Greer et al.   Cell Metabolism

Specificity of the innate immune system and diversity of C-type lectin domain (CTLD) proteins in the nematode Caenorhabditis elegans

(2008) Hinrich Schulenburg et al.   IMMUNOBIOLOGY

Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival

(2008) Patrick Narbonne et al.   NATURE

The Trichoplax genome and the nature of placozoans

(2008) Mansi Srivastava et al.   NATURE

Cholesterol modulates cellular TGF-β responsiveness by altering TGF-β binding to TGF-β receptors

(2007) Chun-Lin Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY