Cilia in Left–Right Symmetry Breaking

Intraciliary Calcium Oscillations Initiate Vertebrate Left-Right Asymmetry

(2015) Shiaulou Yuan et al.   CURRENT BIOLOGY

Absence of Radial Spokes in Mouse Node Cilia Is Required for Rotational Movement but Confers Ultrastructural Instability as a Trade-Off

(2015) Kyosuke Shinohara et al.   DEVELOPMENTAL CELL

9 + 0 and 9 + 2 cilia are randomly dispersed in the mouse node

(2015) Toru Odate et al.   Microscopy

Asymmetric distribution of dynamic calcium signals in the node of mouse embryo during left–right axis formation

(2013) Daisuke Takao et al.   DEVELOPMENTAL BIOLOGY

Picking up speed: advances in the genetics of primary ciliary dyskinesia

(2013) Amjad Horani et al.   PEDIATRIC RESEARCH

Roles of cilia, fluid flow, and Ca2+ signaling in breaking of left–right symmetry

(2013) Satoko Yoshiba et al.   TRENDS IN GENETICS

Cilia at the Node of Mouse Embryos Sense Fluid Flow for Left-Right Determination via Pkd2

(2012) S. Yoshiba et al.   SCIENCE

Two rotating cilia in the node cavity are sufficient to break left–right symmetry in the mouse embryo

(2012) Kyosuke Shinohara et al.   Nature Communications

Fluid flow and interlinked feedback loops establish left–right asymmetric decay of Cerl2 mRNA

(2012) Tetsuya Nakamura et al.   Nature Communications

IP3 signaling is required for cilia formation and left–right body axis determination in Xenopus embryos

(2011) Minoru Hatayama et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pkd1l1 establishes left-right asymmetry and physically interacts with Pkd2

(2011) S. Field et al.   DEVELOPMENT

Pkd1l1 complexes with Pkd2 on motile cilia and functions to establish the left-right axis

(2011) K. Kamura et al.   DEVELOPMENT

Left–right asymmetry in the level of active Nodal protein produced in the node is translated into left–right asymmetry in the lateral plate of mouse embryos

(2011) Aiko Kawasumi et al.   DEVELOPMENTAL BIOLOGY

Three-dimensional structure of basal body triplet revealed by electron cryo-tomography

(2011) Sam Li et al.   EMBO JOURNAL

The Nodal Inhibitor Coco Is a Critical Target of Leftward Flow in Xenopus

(2010) Axel Schweickert et al.   CURRENT BIOLOGY

Translation of anterior–posterior polarity into left–right polarity in the mouse embryo

(2010) Masakazu Hashimoto et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning

(2010) Hai Song et al.   NATURE

Vangl2 directs the posterior tilting and asymmetric localization of motile primary cilia

(2010) Antonia Borovina et al.   NATURE CELL BIOLOGY

Planar polarization of node cells determines the rotational axis of node cilia

(2010) Masakazu Hashimoto et al.   NATURE CELL BIOLOGY

Identification of dyneins that localize exclusively to the proximal portion of Chlamydomonas flagella

(2009) T. Yagi et al.   JOURNAL OF CELL SCIENCE

Molecular architecture of inner dynein arms in situ inChlamydomonas reinhardtiiflagella

(2008) Khanh Huy Bui et al.   JOURNAL OF CELL BIOLOGY