A CK2–RNF4 interplay coordinates non-canonical SUMOylation and degradation of nuclear receptor FXR

The Nuclear Receptor FXR Uncouples the Actions of miR-33 From SREBP-2Significance

(2015) Elizabeth J. Tarling et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Molecular Basis for Phosphorylation-dependent SUMO Recognition by the DNA Repair Protein RAP80

(2015) Anamika et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CDK-mediated RNF4 phosphorylation regulates homologous recombination in S-phase

(2015) K. Luo et al.   NUCLEIC ACIDS RESEARCH

Farnesoid X receptor, the bile acid sensing nuclear receptor, in liver regeneration

(2015) Guodong Li et al.   Acta Pharmaceutica Sinica B

A dysregulated acetyl/SUMO switch of FXR promotes hepatic inflammation in obesity

(2014) D.-H. Kim et al.   EMBO JOURNAL

Oxidative stress–induced assembly of PML nuclear bodies controls sumoylation of partner proteins

(2014) Umut Sahin et al.   JOURNAL OF CELL BIOLOGY

SUMO Chain-Induced Dimerization Activates RNF4

(2014) Alejandro Rojas-Fernandez et al.   MOLECULAR CELL

SUMOylation of the Farnesoid X Receptor (FXR) Regulates the Expression of FXR Target Genes

(2013) Natarajan Balasubramaniyan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-inflammatory and metabolic actions of FXR: Insights into molecular mechanisms

(2012) Danielle A.A. Hollman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The SUMO E3-ligase PIAS1 Regulates the Tumor Suppressor PML and Its Oncogenic Counterpart PML-RARA

(2012) A. Rabellino et al.   CANCER RESEARCH

Promotion of liver regeneration/repair by farnesoid X receptor in both liver and intestine in mice

(2012) Lisheng Zhang et al.   HEPATOLOGY

Identification of Estrogen Receptor   as a SUMO-1 Target Reveals a Novel Phosphorylated Sumoylation Motif and Regulation by Glycogen Synthase Kinase 3 

(2012) N. Picard et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR

(2012) Anna C. Calkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Coordinate regulation of estrogen receptor β degradation by Mdm2 and CREB-binding protein in response to growth signals

(2012) M Sanchez et al.   ONCOGENE

SUMOylation-regulated Protein Phosphorylation, Evidence from Quantitative Phosphoproteomics Analyses

(2011) Qi Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Functional Roles of Daxx SIM Phosphorylation in SUMO Paralog-Selective Binding and Apoptosis Modulation

(2011) Che-Chang Chang et al.   MOLECULAR CELL

Transcriptional control of metabolic and inflammatory pathways by nuclear receptor SUMOylation

(2010) Eckardt Treuter et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cellular regulators of protein kinase CK2

(2010) Mathias Montenarh   CELL AND TISSUE RESEARCH

Role of SUMO in RNF4-mediated Promyelocytic Leukemia Protein (PML) Degradation

(2009) Yann Percherancier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Bile Acid Receptor FXR Is a Modulator of Intestinal Innate Immunity

(2009) P. Vavassori et al.   JOURNAL OF IMMUNOLOGY

Phospho-Regulated SUMO Interaction Modules Connect the SUMO System to CK2 Signaling

(2009) Per Stehmeier et al.   MOLECULAR CELL

A molecular basis for phosphorylation-dependent SUMO conjugation by the E2 UBC9

(2009) Firaz Mohideen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

(2009) Philippe Lefebvre et al.   PHYSIOLOGICAL REVIEWS

Challenging estrogen receptor β with phosphorylation

(2009) Mélanie Sanchez et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY

Too much of a good thing: The role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2

(2007) James S. Duncan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Phosphorylation-Dependent Sumoylation Regulates Estrogen-Related Receptor-α and -γ Transcriptional Activity through a Synergy Control Motif

(2007) Annie M. Tremblay et al.   MOLECULAR ENDOCRINOLOGY

Phosphorylation of Activation Function-1 Regulates Proteasome-Dependent Nuclear Mobility and E6-Associated Protein Ubiquitin Ligase Recruitment to the Estrogen Receptor β

(2007) Nathalie Picard et al.   MOLECULAR ENDOCRINOLOGY