The steady-state level of CDK4 protein is regulated by antagonistic actions between PAQR4 and SKP2 and involved in tumorigenesis

A Golgi-specific protein PAQR3 is closely associated with the progression, metastasis and prognosis of human gastric cancers

(2014) Z. Q. Ling et al.   ANNALS OF ONCOLOGY

C/EBPα regulates CRL4Cdt2-mediated degradation of p21 in response to UVB-induced DNA damage to control the G1/S checkpoint

(2014) Jonathan R Hall et al.   CELL CYCLE

Skp2: A dream target in the coming age of cancer therapy

(2014) Chia-Hsin Chan et al.   CELL CYCLE

Ubiquitin Ligases and Cell Cycle Control

(2013) Leonardo K. Teixeira et al.   Annual Review of Biochemistry

ZNF313 is a novel cell cycle activator with an E3 ligase activity inhibiting cellular senescence by destabilizing p21WAF1

(2013) J Han et al.   CELL DEATH AND DIFFERENTIATION

PD-0332991, a CDK4/6 Inhibitor, Significantly Prolongs Survival in a Genetically Engineered Mouse Model of Brainstem Glioma

(2013) Kelly L. Barton et al.   PLoS One

A Systematic Screen for CDK4/6 Substrates Links FOXM1 Phosphorylation to Senescence Suppression in Cancer Cells

(2011) Lars Anders et al.   CANCER CELL

Functional Cooperation of RKTG with p53 in Tumorigenesis and Epithelial-Mesenchymal Transition

(2011) Y. Jiang et al.   CANCER RESEARCH

PAQR10 and PAQR11 mediate Ras signaling in the Golgi apparatus

(2011) Ting Jin et al.   CELL RESEARCH

Proliferative Suppression by CDK4/6 Inhibition: Complex Function of the Retinoblastoma Pathway in Liver Tissue and Hepatoma Cells

(2010) Dayana B. Rivadeneira et al.   GASTROENTEROLOGY

Clinical and Biological Significance of CDK4 Amplification in Well-Differentiated and Dedifferentiated Liposarcomas

(2009) A. Italiano et al.   CLINICAL CANCER RESEARCH

Multi-stage chemical carcinogenesis in mouse skin: Fundamentals and applications

(2009) Erika L Abel et al.   Nature Protocols

Crystal structure of human CDK4 in complex with a D-type cyclin

(2009) P. J. Day et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RKTG sequesters B-Raf to the Golgi apparatus and inhibits the proliferation and tumorigenicity of human malignant melanoma cells

(2008) Fengjuan Fan et al.   CARCINOGENESIS

Suppressive function of RKTG on chemical carcinogen-induced skin carcinogenesis in mouse

(2008) X. Xie et al.   CARCINOGENESIS